Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2023, Vol. 37 ›› Issue (4): 1-12.doi: 10.6040/j.issn.1673-3770.0.2023.137

   

Classification, pathogenesis, and treatment advances of chronic subjective tinnitus

CHEN Zhuoyi, ZHENG Yiqing, YANG Haidi   

  1. Department of Otorhinolaryngology & Head and Neck Surgery, Sun Yat Sen Mem Hospital, Sun Yat Sen University, Guangzhou 510120, Guangdong, China
  • Published:2023-07-27

Abstract: Chronic subjective tinnitus characterized by a high incidence rate, diverse clinical manifestations, and a complex pathological mechanism, is a common symptom in otolaryngology. Tinnitus classification and research on its neurophysiological mechanisms serve as a basis for guiding clinical diagnosis and individualized precision medical treatment. In recent years, an increasing number of tinnitus studies have introduced novel concepts in these domains. Emerging evidence shows that dimensional variability of tinnitus characteristics may provide a more accurate understanding of the heterogeneous nature of tinnitus compared to traditional subtype classification, thereby holding significant potential for clinical research and diagnosis applications. In addition, a newly developed tinnitus network model, integrates the neurophysiological mechanisms of tinnitus and its associated complications, further advancing the theoretical basis for individualized tinnitus treatment. This article provides a summary of the dimensional network model for tinnitus classification and the triple network model of tinnitus-associated complications. Additionally, it briefly outlines the common treatment methods for tinnitus incorporating updated guidelines and the latest evidence-based medicine, providing a valuable reference for readers.

Key words: Chronic subjective tinnitus, Classification method, Pathogenesis, Brain network, Treatment.

CLC Number: 

  • R764.45
[1] Jarach CM, Lugo A, Scala M, et al. Global prevalence and incidence of tinnitus: a systematic review and meta-analysis[J]. JAMA Neurol, 2022, 79(9): 888-900. doi:10.1001/jamaneurol.2022.2189
[2] Yang HD, Cai YX, Guo HP, et al. Prevalence and factors associated with tinnitus: data from adult residents in Guangdong Province, South of China[J]. Int J Audiol, 2018, 57(12): 892-899. doi:10.1080/14992027.2018.1506169
[3] 贺璐, 王国鹏, 龚树生. 解读美国《耳鸣临床应用指南》[J]. 中华耳科学杂志, 2016, 14(2): 149-152. doi:10.3969/j.issn.1672-2922.2016.02.004 HE Lu, WANG Guopeng, GONG Shusheng. Interpretation of the AAO-HSN clinical practice guideline: tinnitus[J]. Chinese Journal of Otology, 2016, 14(2): 149-152. doi:10.3969/j.issn.1672-2922.2016.02.004
[4] 刘蓬, 郑芸, 卢兢哲, 等. 《欧洲多学科耳鸣指南: 诊断、评估和治疗》解读[J]. 听力学及言语疾病杂志, 2020, 28(6): 727-732. doi:10.3969/j.issn.1006-7299.2020.06.029 LIU Peng, ZHENG Yun, LU Jingzhe, et al. Interpretation of European multidisciplinary tinnitus guidelines: diagnosis, evaluation and treatment[J]. Journal of Audiology and Speech Pathology, 2020, 28(6): 727-732. doi:10.3969/j.issn.1006-7299.2020.06.029
[5] 余力生, 杨仕明, 王秋菊, 等. 耳鸣的诊断与治疗[J]. 临床耳鼻咽喉头颈外科杂志, 2022, 36(5): 325-334. doi:10.13201/j.issn.2096-7993.2022.05.001 YU Lisheng, YANG Shiming, WANG Qiuju, et al. Diagnosis and treatment of tinnitus[J]. Journal of Clinical Otorhinolaryngology Head and Neck Surgery, 2022, 36(5): 325-334. doi:10.13201/j.issn.2096-7993.2022.05.001
[6] 刘广宇, 张剑宁, 黄平, 等. 国内耳鸣文献回顾与思考[J]. 中华耳科学杂志, 2022, 20(5): 845-850. doi:10.3969/j.issn.1672-2922.2022.05.026 LIU Guangyu, ZHANG Jianning, HUANG Ping, et al. A review and reflection on domestic literatures on tinnitus[J]. Chinese Journal of Otology, 2022, 20(5): 845-850. doi:10.3969/j.issn.1672-2922.2022.05.026
[7] Tunkel DE, Bauer CA, Sun GH, et al. American academy of otolaryngology—head and neck foundation clinical practice guideline: tinnitus[J]. Otolaryngol - head Neck Surg, 2014, 151(S1). doi:10.1177/0194599814538403a56
[8] Cederroth CR, Gallus S, Hall DA, et al. Editorial: towards an understanding of tinnitus heterogeneity[J]. Front Aging Neurosci, 2019, 11: 53. doi:10.3389/fnagi.2019.00053
[9] Tzounopoulos T, Balaban C, Zitelli L, et al. Towards a mechanistic-driven precision medicine approach for tinnitus[J]. J Assoc Res Otolaryngol, 2019, 20(2): 115-131. doi:10.1007/s10162-018-00709-9
[10] Genitsaridi E, Hoare DJ, Kypraios T, et al. A review and a framework of variables for defining and characterizing tinnitus subphenotypes[J]. Brain Sci, 2020, 10(12): 938. doi:10.3390/brainsci10120938
[11] Henton A, Tzounopoulos T. What's the buzz? the neuroscience and the treatment of tinnitus[J]. Physiol Rev, 2021, 101(4): 1609-1632. doi:10.1152/physrev.00029.2020
[12] 王楠, 黄晶, 彭涛, 等. OSAHS与耳鸣的相关性研究现状[J]. 山东大学耳鼻喉眼学报, 2023, 37(2): 122-127. doi: 10.6040/j.issn.1673-3770.0.2021.518 WANG Nan, HUANG Jing, PENG Tao, et al. Current research on the relationship between obstructive sleep apnea hypopnea syndrome and tinnitus[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2023, 37(2): 122-127. doi: 10.6040/j.issn.1673-3770.0.2021.518
[13] van den Berge MJC, Free RH, Arnold R, et al. Cluster analysis to identify possible subgroups in tinnitus patients[J]. Front Neurol, 2017, 8: 115. doi:10.3389/fneur.2017.00115
[14] Santacruz JL, de Kleine E, van Dijk P. Investigating the relation between minimum masking levels and hearing thresholds for tinnitus subtyping[J]. Prog Brain Res, 2021, 263: 81-94. doi:10.1016/bs.pbr.2021.04.011
[15] Mohan A, Leong SL, de Ridder D, et al. Symptom dimensions to address heterogeneity in tinnitus[J]. Neurosci Biobehav Rev, 2022, 134: 104542. doi:10.1016/j.neubiorev.2022.104542
[16] Cuthbert BN. The RDoC framework: facilitating transition from ICD/DSM to dimensional approaches that integrate neuroscience and psychopathology[J]. World Psychiatry, 2014, 13(1): 28-35. doi:10.1002/wps.20087
[17] Vanneste S, Alsalman O, De Ridder D. Top-down and bottom-up regulated auditory phantom perception[J]. J Neurosci, 2019,39(2):364-378. doi: 10.1523/JNEUROSCI.0966-18.2018
[18] Jackson P. A comparison of the effects of eighth nerve section with lidocaine on tinnitus[J]. J Laryngol Otol, 1985, 99(7): 663-666. doi:10.1017/s0022215100097449
[19] 罗扬拓, 冯帅, 姜学钧, 等. 听觉中枢可塑性与耳鸣发生机制的研究进展[J]. 临床耳鼻咽喉头颈外科杂志, 2021, 35(11): 1038-1041. doi:10.13201/j.issn.2096-7993.2021.11.017 LUO Yangtuo, FENG Shuai, JIANG Xuejun, et al. Research progress in auditory center plasticity and tinnitus mechanism[J]. Journal of Clinical Otorhinolaryngology Head and Neck Surgery, 2021, 35(11): 1038-1041. doi:10.13201/j.issn.2096-7993.2021.11.017
[20] De Ridder D, Adhia D, Vanneste S. The anatomy of pain and suffering in the brain and its clinical implications[J]. Neurosci Biobehav Rev, 2021, 130: 125-146. doi:10.1016/j.neubiorev.2021.08.013
[21] 周腊梅, 蒋雯, 刘稳, 等. 持续性特发性耳鸣严重程度的相关因素分析[J]. 山东大学耳鼻喉眼学报, 2021, 35(6): 70-76. doi:10.6040/j.issn.1673-3770.0.2021.009 ZHOU Lamei, JIANG Wen, LIU Wen, et al. Analysis of factors related to the severity of persistent idiopathic tinnitus[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(6): 70-76. doi:10.6040/j.issn.1673-3770.0.2021.009
[22] 张域开, 宋勇莉, 齐柳, 等. 慢性耳鸣的临床特点及严重程度影响因素分析[J]. 听力学及言语疾病杂志, 2022, 30(6): 627-631. doi:10.3969/j.issn.1006-7299.2022.06.013 ZHANG Yukai, SONG Yongli, QI Liu, et al. Analysis of clinical characteristics and influencing factors of severity of chronic tinnitus[J]. Journal of Audiology and Speech Pathology, 2022, 30(6): 627-631. doi:10.3969/j.issn.1006-7299.2022.06.013
[23] Axelsson A, Ringdahl A. Tinnitus: a study of its prevalence and characteristics[J]. Br J Audiol, 1989, 23(1): 53-62. doi:10.3109/03005368909077819
[24] De Ridder D, Schlee W, Vanneste S, et al. Tinnitus and tinnitus disorder: theoretical and operational definitions(an international multidisciplinary proposal)[J]. Prog Brain Res, 2021, 260: 1-25. doi:10.1016/bs.pbr.2020.12.002
[25] Handscomb L, Shorter GW, Hoare DJ, et al. Evaluation of a cognitive behavioral model of tinnitus distress: a cross-sectional study using structural equation modeling[J]. Ear Hear, 2020, 41(4): 1028-1039. doi:10.1097/AUD.0000000000000826
[26] Schmidt CJ, Kerns RD, Griest S, et al. Toward development of a tinnitus magnitude index[J]. Ear Hear, 2014, 35(4): 476-484. doi:10.1097/AUD.0000000000000017
[27] Buzsáki G. The brain-cognitive behavior problem: a retrospective[J]. eNeuro, 2020, 7(4): ENEURO.0069-ENEURO.0020.2020. doi:10.1523/eneuro.0069-20.2020
[28] De Ridder D, Vanneste S. Burst and tonic spinal cord stimulation: different and common brain mechanisms[J]. Neuromodulation, 2016, 19(1): 47-59. doi:10.1111/ner.12368
[29] De Ridder D, Vanneste S. The Bayesian brain in imbalance: Medial, lateral and descending pathways in tinnitus and pain: a perspective[J]. Prog Brain Res, 2021, 262: 309-334. doi:10.1016/bs.pbr.2020.07.012
[30] Sha ZQ, Wager TD, Mechelli A, et al. Common dysfunction of large-scale neurocognitive networks across psychiatric disorders[J]. Biol Psychiatry, 2019, 85(5): 379-388. doi:10.1016/j.biopsych.2018.11.011
[31] Cima RFF, Crombez G, Vlaeyen JWS. Catastrophizing and fear of tinnitus predict quality of life in patients with chronic tinnitus[J]. Ear Hear, 2011, 32(5): 634-641. doi:10.1097/AUD.0b013e31821106dd
[32] Clarke NA, Akeroyd MA, Henshaw H, et al. The executive disruption model of tinnitus distress: model validation in two independent datasets using factor score regression[J]. Front Psychol, 2023, 14: 1006349. doi:10.3389/fpsyg.2023.1006349
[33] De Ridder D, Vanneste S, Song JJ, et al. Tinnitus and the triple network model: a perspective[J]. Clin Exp Otorhinolaryngol, 2022, 15(3): 205-212. doi:10.21053/ceo.2022.00815
[34] Schmidt SA, Carpenter-Thompson J, Husain FT. Connectivity of precuneus to the default mode and dorsal attention networks: a possible invariant marker of long-term tinnitus[J]. Neuroimage Clin, 2017, 16: 196-204. doi:10.1016/j.nicl.2017.07.015
[35] Lee SY, Choi BY, Koo JW, et al. Cortical oscillatory signatures reveal the prerequisites for tinnitus perception: a comparison of subjects with sudden sensorineural hearing loss with and without tinnitus[J]. Front Neurosci, 2020, 14: 596647. doi:10.3389/fnins.2020.596647
[36] Han JJ, Ridder D, Vanneste S, et al. Pre-treatment ongoing cortical oscillatory activity predicts improvement of tinnitus after partial peripheral reafferentation with hearing aids[J]. Front Neurosci, 2020, 14: 410. doi:10.3389/fnins.2020.00410
[37] Clarke NA, Henshaw H, Akeroyd MA, et al. Associations between subjective tinnitus and cognitive performance: systematic review and meta-analyses[J]. Trends Hear, 2020, 24: 2331216520918416. doi:10.1177/2331216520918416
[38] Poeppel D, Adolfi F. Against the epistemological primacy of the hardware: the brain from inside out, turned upside down[J]. eNeuro, 2020, 7(4): ENEURO.0215-ENEURO.0220.2020. doi:10.1523/ENEURO.0215-20.2020
[39] Lee SJ, Park J, Lee SY, et al. Triple network activation causes tinnitus in patients with sudden sensorineural hearing loss: a model-based volume-entropy analysis[J]. Front Neurosci, 2022, 16: 1028776. doi:10.3389/fnins.2022.1028776
[40] Cima RFF, Kikidis D, Mazurek B, et al. Tinnitus healthcare: a survey revealing extensive variation in opinion and practices across Europe[J]. BMJ Open, 2020, 10(1): e029346. doi:10.1136/bmjopen-2019-029346
[41] Fuller TE, Haider HF, Kikidis D, et al. Different teams, same conclusions? A systematic review of existing clinical guidelines for the assessment and treatment of tinnitus in adults[J]. Front Psychol, 2017, 8: 206. doi:10.3389/fpsyg.2017.00206
[42] Cima RFF, Mazurek B, Haider H, et al. A multidisciplinary European guideline for tinnitus: diagnostics, assessment, and treatment[J]. HNO, 2019, 67(1): 10-42. doi:10.1007/s00106-019-0633-7
[43] Ogawa K, Sato H, Takahashi M, et al. Clinical practice guidelines for diagnosis and treatment of chronic tinnitus in Japan[J]. Auris Nasus Larynx, 2020, 47(1): 1-6. doi:10.1016/j.anl.2019.09.007
[44] Lewis S, Chowdhury E, Stockdale D, et al. Assessment and management of tinnitus: summary of NICE guidance[J]. BMJ, 2020, 368: m976. doi:10.1136/bmj.m976
[45] Mazurek B, Hesse G, Dobel C, et al. Chronic Tinnitus[J]. Dtsch Arztebl Int, 2022,119(13):219-225. doi: 10.3238/arztebl.m2022.0135
[46] Kreuzer PM, Vielsmeier V, Langguth B. Chronic tinnitus: an interdisciplinary challenge[J]. Dtsch Arztebl Int, 2013, 110(16): 278-284. doi:10.3238/arztebl.2013.0278
[47] 李明, 黄平. 耳鸣综合疗法[J]. 中国中西医结合耳鼻咽喉科杂志, 2020, 28(5): 322-323. doi:10.16542/j.cnki.issn.1007-4856.2020.05.002 LI Ming, HUANG Ping. Comprehensive treatment of tinnitus[J]. Chinese Journal of Otorhinolaryngology in Integrative Medicine, 2020, 28(5): 322-323. doi:10.16542/j.cnki.issn.1007-4856.2020.05.002
[48] Searchfield GD, Kaur M, Martin WH. Hearing aids as an adjunct to counseling: tinnitus patients who choose amplification do better than those that don't[J]. Int J Audiol, 2010, 49(8): 574-579. doi:10.3109/14992021003777267
[49] Piromchai P, Srisukhumchai C, Kasemsiri P, et al. A three-arm, single-blind, randomized controlled trial examining the effects of notched music therapy, conventional music therapy, and counseling on tinnitus[J]. Otol Neurotol, 2021, 42(2): 335-340. doi:10.1097/MAO.0000000000002935
[50] Schoisswohl S, Langguth B, Schecklmann M, et al. Unification of Treatments and Interventions for Tinnitus Patients(UNITI): a study protocol for a multi-center randomized clinical trial[J]. Trials, 2021, 22(1): 875. doi:10.1186/s13063-021-05835-z
[51] Rademaker MM, Stegeman I, Ho-Kang-You KE, et al. The effect of mindfulness-based interventions on tinnitus distress. A systematic review[J]. Front Neurol, 2019, 10: 1135. doi:10.3389/fneur.2019.01135
[52] Fuller T, Cima R, Langguth B, et al. Cognitive behavioural therapy for tinnitus[J]. Cochrane Database Syst Rev, 2020, 1(1): CD012614. doi:10.1002/14651858.CD012614.pub2
[53] Husain FT, Zimmerman B, Tai Y, et al. Assessing mindfulness-based cognitive therapy intervention for tinnitus using behavioural measures and structural MRI: a pilot study[J]. Int J Audiol, 2019, 58(12): 889-901. doi:10.1080/14992027.2019.1629655
[54] 卢兢哲,钟萍,郑芸.欧洲多学科耳鸣指南:诊断、评估和治疗[J].听力学及言语疾病杂志,2020,28(1):110-114.
[55] Mehdi M, Riha C, Neff P, et al. Smartphone apps in the context of tinnitus: systematic review[J]. Sensors, 2020, 20(6): 1725. doi:10.3390/s20061725
[56] Malinvaud D, Londero A, Niarra R, et al. Auditory and visual 3D virtual reality therapy as a new treatment for chronic subjective tinnitus: results of a randomized controlled trial[J]. Hear Res, 2016, 333: 127-135. doi:10.1016/j.heares.2015.12.023
[57] Biswas R, Genitsaridi E, Trpchevska N, et al. Low evidence for tinnitus risk factors: a systematic review and meta-analysis[J]. J Assoc Res Otolaryngol, 2023, 24(1): 81-94. doi:10.1007/s10162-022-00874-y
[58] Yakunina N, Lee WH, Ryu YJ, et al. Tinnitus suppression effect of hearing aids in patients with high-frequency hearing loss: a randomized double-blind controlled trial[J]. Otol Neurotol, 2019, 40(7): 865-871. doi:10.1097/MAO.0000000000002315
[59] 高敏倩, 党华, 吴钰婷, 等. 助听器治疗慢性主观性耳鸣的长期疗效[J]. 中国耳鼻咽喉头颈外科, 2019, 26(3): 142-145. doi:10.16066/j.1672-7002.2019.03.007 GAO Minqian, DANG Hua, WU Yuting, et al. Long-term effect of hearing aid on chronic subjective tinnitus[J]. Chinese Archives of Otolaryngology-Head and Neck Surgery, 2019, 26(3): 142-145. doi:10.16066/j.1672-7002.2019.03.007
[60] Sereda M, Xia J, El Refaie A, et al. Sound therapy(using amplification devices and/or sound generators)for tinnitus[J]. Cochrane Database Syst Rev, 2018, 12(12): CD013094. doi:10.1002/14651858.CD013094.pub2
[61] Waechter S, Jönsson A. Hearing aids mitigate tinnitus, but does it matter if the patient receives amplification in accordance with their hearing impairment or not? A meta-analysis[J]. Am J Audiol, 2022, 31(3): 789-818. doi:10.1044/2022_AJA-22-00004
[62] Borges ALF, Duarte PLES, Almeida RBS, et al. Cochlear implant and tinnitus-a meta-analysis[J]. Braz J Otorhinolaryngol, 2021, 87(3): 353-365. doi:10.1016/j.bjorl.2020.11.006
[63] Daher GS, Kocharyan A, Dillon MT, et al. Cochlear implantation outcomes in adults with single-sided deafness: a systematic review and meta-analysis[J]. Otol Neurotol, 2023, 44(4): 297-309. doi:10.1097/MAO.0000000000003833
[64] Oh SJ, Mavrommatis MA, Fan CJ, et al. Cochlear implantation in adults with single-sided deafness: a systematic review and meta-analysis[J]. Otolaryngol Head Neck Surg, 2023, 168(2): 131-142. doi:10.1177/01945998221083283
[65] 杨仕明, 王倩. 人工耳蜗植入抑制耳鸣与听觉中枢神经调控[J]. 听力学及言语疾病杂志, 2022, 30(4): 347-349. doi:10.3969/j.issn.1006-7299.2022.04.001 YANG Shiming, WANG Qian. Cochlear Implantation Inhibits Tinnitus and auditory pathway Nerve Regulation[J]. Journal of Audiology and Speech Pathology, 2022, 30(4): 347-349. doi:10.3969/j.issn.1006-7299.2022.04.001
[66] Alzahrani L, Sereda M, Chamouton CS, et al. Experience of tinnitus in adults who have severe-to-profound hearing loss: a scoping review[J]. Front Neurol, 2022, 13: 1004059. doi:10.3389/fneur.2022.1004059
[67] 王欣怡, 杨文杰, 余文兴, 等. 家庭化个体多元复合声治疗对耳鸣伴听力损失患者的疗效及影响因素分析[J]. 山东大学耳鼻喉眼学报, 2022, 36(6): 70-76. doi:10.6040/j.issn.1673-3770.0.2022.327 WANG Xinyi, YANG Wenjie, YU Wenxing, et al. Effects and influencing factors of family-oriented customized sound therapy on patients with tinnitus and hearing loss[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(6): 70-76. doi:10.6040/j.issn.1673-3770.0.2022.327
[68] Neff P, Zielonka L, Meyer M, et al. Comparison of amplitude modulated sounds and pure tones at the tinnitus frequency: residual tinnitus suppression and stimulus evaluation[J]. Trends Hear, 2019, 23: 2331216519833841. doi:10.1177/2331216519833841
[69] Tong ZP, Deng WT, Huang XY, et al. Efficacy of tailor-made notched music training versus tinnitus retraining therapy in adults with chronic subjective tinnitus: a randomized controlled clinical trial[J]. Ear Hear, 2023, 44(4): 670-681. doi:10.1097/AUD.0000000000001318
[70] Langguth B, Kleinjung T, Schlee W, et al. Tinnitus guidelines and their evidence base[J]. J Clin Med, 2023, 12(9): 3087. doi:10.3390/jcm12093087
[71] Stein A, Wunderlich R, Lau P, et al. Clinical trial on tonal tinnitus with tailor-made notched music training[J]. BMC Neurol, 2016, 16: 38. doi:10.1186/s12883-016-0558-7
[72] Tinnitus Retraining Therapy Trial Research Group, Scherer RW, Formby C. Effect of tinnitus retraining therapy vs standard of care on tinnitus-related quality of life: a randomized clinical trial[J]. JAMA Otolaryngol Head Neck Surg, 2019, 145(7): 597-608. doi:10.1001/jamaoto.2019.0821
[73] Attarha M, Bigelow J, Merzenich MM. Unintended consequences of white noise therapy for tinnitus-otolaryngology's cobra effect: a review[J]. JAMA Otolaryngol Head Neck Surg, 2018, 144(10): 938-943. doi:10.1001/jamaoto.2018.1856
[74] 冯天赐, 杨海弟, 高敏倩, 等. 音乐联合认知行为疗法治疗主观性耳鸣及脑电图变化[J]. 中国耳鼻咽喉头颈外科, 2019, 26(1): 25-30. doi:10.16066/j.1672-7002.2019.01.007 FENG Tianci, YANG Haidi, GAO Minqian, et al. Effectiveness of music combined cognitive behavior therapy on subjective tinnitus and observation of changes of resting-state EEG[J]. Chinese Archives of Otolaryngology-Head and Neck Surgery, 2019, 26(1): 25-30. doi:10.16066/j.1672-7002.2019.01.007
[75] 陈炜, 张莉, 周林路, 等. 认知行为疗法联合声治疗对慢性特发性耳鸣的疗效及影响因素分析[J]. 听力学及言语疾病杂志, 2023, 31(1): 22-25. doi:10.3969/j.issn.1006-7299.2023.01.005 CHEN Wei, ZHANG Li, ZHOU Linlu, et al. Effect of cognitive behavioral therapy combined with sound therapy on chronic idiopathic tinnitus and its influence factor[J]. Journal of Audiology and Speech Pathology,2023, 31(1): 22-25. doi:10.3969/j.issn.1006-7299.2023.01.005
[76] 杨双凤, 涂敏, 谭裕玲, 等. 主观性耳鸣脑功能网络调控的研究进展[J]. 中华神经医学杂志, 2023, 22(1): 101-104. doi:10.3760/cma.j.cn115354-20220713-00495 YANG Shuangfeng, TU Min, TAN Yuling, et al. Recent advance in brain functional network in subjective tinnitus[J]. Chinese Journal of Neuromedicine, 2023, 22(1): 101-104. doi:10.3760/cma.j.cn115354-20220713-00495
[77] Martins ML, Souza DDS, Cavalcante MEOB, et al. Effect of transcranial Direct Current Stimulation for tinnitus treatment: a systematic review and meta-analysis[J]. Neurophysiol Clin, 2022, 52(1): 1-16. doi:10.1016/j.neucli.2021.12.005
[78] Liang ZR, Yang HD, Cheng G, et al. Repetitive transcranial magnetic stimulation on chronic tinnitus: a systematic review and meta-analysis[J]. BMC Psychiatry, 2020, 20(1): 547. doi:10.1186/s12888-020-02947-9
[79] Lefebvre-Demers M, Doyon N, Fecteau S. Non-invasive neuromodulation for tinnitus: a meta-analysis and modeling studies[J]. Brain Stimul, 2021, 14(1): 113-128. doi:10.1016/j.brs.2020.11.014
[80] Dong CH, Chen C, Wang T, et al. Low-frequency repetitive transcranial magnetic stimulation for the treatment of chronic tinnitus: a systematic review and meta-analysis of randomized controlled trials[J]. Biomed Res Int, 2020, 2020: 3141278. doi:10.1155/2020/3141278
[81] Chen JJ, Zeng BS, Wu CN, et al. Association of central noninvasive brain stimulation interventions with efficacy and safety in tinnitus management: a meta-analysis[J]. JAMA Otolaryngol Head Neck Surg, 2020, 146(9): 801-809. doi:10.1001/jamaoto.2020.1497
[82] Rammo R, Ali R, Pabaney A, et al. Surgical neuromodulation of tinnitus: a review of current therapies and future applications[J]. Neuromodulation, 2019, 22(4): 380-387. doi:10.1111/ner.12793
[83] van Zwieten G, Roberts MJ, Schaper FLVW, et al. Noise-induced neurophysiological alterations in the rat medial geniculate body and thalamocortical desynchronization by deep brain stimulation[J]. J Neurophysiol, 2021, 125(2): 661-671. doi:10.1152/jn.00752.2019
[84] De Ridder D, Adhia D, Langguth B. Tinnitus and brain stimulation[J]. Curr Top Behav Neurosci, 2021, 51: 249-293. doi:10.1007/7854_2021_219
[85] Marks KL, Martel DT, Wu C, et al. Auditory-somatosensory bimodal stimulation desynchronizes brain circuitry to reduce tinnitus in guinea pigs and humans[J]. Sci Transl Med, 2018, 10(422): eaal3175. doi:10.1126/scitranslmed.aal3175
[86] Conlon B, Langguth B, Hamilton C, et al. Bimodal neuromodulation combining sound and tongue stimulation reduces tinnitus symptoms in a large randomized clinical study[J]. Sci Transl Med, 2020, 12(564): eabb2830. doi:10.1126/scitranslmed.abb2830
[87] Güntensperger D, Thüring C, Meyer M, et al. Neurofeedback for tinnitus treatment - review and current concepts[J]. Front Aging Neurosci, 2017, 9: 386. doi:10.3389/fnagi.2017.00386
[88] Riha C, Güntensperger D, Kleinjung T, et al. Recovering hidden responder groups in individuals receiving neurofeedback for tinnitus[J]. Front Neurosci, 2022, 16: 867704. doi:10.3389/fnins.2022.867704
[89] Liu DL, Hu Y, Wang DL, et al. Herbal medicines in the treatment of tinnitus: an updated review[J]. Front Pharmacol, 2022, 13: 1037528. doi:10.3389/fphar.2022.1037528
[90] Witkin JM, Lippa A, Smith JL, et al. Can GABAkines quiet the noise? The GABAA receptor neurobiology and pharmacology of tinnitus[J]. Biochem Pharmacol, 2022, 201: 115067. doi:10.1016/j.bcp.2022.115067
[91] Xu XP, Xie H, Liu ZF, et al. Effects of acupuncture on the outcome of tinnitus: an overview of systematic reviews[J]. Front Neurol, 2022, 13: 1061431. doi:10.3389/fneur.2022.1061431
[92] Bousema EJ, Koops EA, van Dijk P, et al. Effects of physical interventions on subjective tinnitus, a systematic review and meta-analysis[J]. Brain Sci, 2023, 13(2): 226. doi:10.3390/brainsci13020226
[93] Huang KY, Liang S, Chen L, et al. Acupuncture for tinnitus: a systematic review and meta-analysis of randomized controlled trials[J]. Acupunct Med, 2021, 39(4): 264-271. doi:10.1177/0964528420938380
[94] Jarach CM, Lugo A, Garavello W, et al. The role of diet in tinnitus onset: a hospital-based case-control study from Italy[J]. Nutrients, 2023, 15(3): 621. doi:10.3390/nu15030621
[95] Marcrum SC, Engelke M, Goedhart H, et al. The influence of diet on tinnitus severity: results of a large-scale, online survey[J]. Nutrients, 2022, 14(24): 5356. doi:10.3390/nu14245356
[1] LI Lu, ZHAO Jie, ZHAO Bojun. Research progress on the pathogenesis and treatments of central serous chorioretinopathy [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2023, 37(3): 118-124.
[2] WANG Xingxin, YANG Xinyu, ZHENG Xiaojun, DING Lin, SHENG Yawen, BI Xiaoyun, YANG Jiguo. Acupoint application therapy for adenoid hypertrophy in children: a case report [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(5): 122-124.
[3] LIN Hai, ZHU Ying,ZHANG Weitian. The roles of ion channels in the pathogenesis of chronic rhinosinusitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(3): 64-70.
[4] LI Jiani, ZHU Dongdong,MENG Cuida. The role of epigenetics in the pathogenesis of chronic rhinosinusitis with nasal polyps [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(3): 84-91.
[5] HAN Yingying,LI Yanzhong. Obstructive sleep apnea hypopnea syndrome and subclinical arteriosclerosis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(2): 126-132.
[6] WANG Yuting,,WANG Jiaxi. Research developments on microRNA in the pathogenesis of allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(5): 98-104.
[7] XIANG Liulan, YE Yuanhang,JIANG Luyun, LIU Yang. Elucidating the role and mechanism of Tim-3 in allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(6): 118-122.
[8] ZHU Zhengru,ZHANG Xiaobing. Correlation between high-mobility group box-1 and allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(6): 123-128.
[9] LIN XiaoqinOverview,WU MiaoqinGuidance. Pathogenesis and treatment of idiopathic epiretinal membranes [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(2): 121-128.
[10] Huabin LI,Yuting LAI,Wenxiu JIANG. Endotypes and precision medicine in chronic sinusitis treatment [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(3): 9-13.
[11] SUN Ziwen, CUI Hongwei, SUN Xiling, CHEN Chen, ZHANG Lu, HU Zhulin. SUN Ziwen1, CUI Hongwei2, SUN XilingEtiology, pathogenesis, and management of dry eye [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(2): 159-166.
[12] Yu ZHANG,Xicheng SONG. Advances in interaction mechanisms and treatment strategy between chronic rhinosinusitis with nasal polyp and asthma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 49-52.
[13] ZHANG Ruxin. Prospect and progress of allergic rhinitis. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(4): 3-6.
[14] YANG Zi-chao, WANG Yu-liang. Etiology, mechanism of dye eye and advancement of traditional Chinese medicine in combination with western medicine for it [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(2): 91-93.
[15] ZHANG Chan-juan, LI Yan-zhong, WANG Yan. The relationship between brain derived neurotrophic factor and obstructive sleep apnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(1): 8-11.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!