Abstract: Objective To investigate the effect of laserassisted subepithelial keratectomy（LASEK）for the correction of high myopia. Methods LASEK was performed on 54 eyes of 27 myopia patients. The preoperative mean spherical (MSE) was -6.00～-14.00D, average（-8.75±1.27）D. Postoperative uncorrected visual acuity(UCVA), refractive power, time of epithelial healing and corneal haze were all recorded. Patients were followedup for 6 months. Results No serious complications occurred. The epithelium was healed in a mean （3.71±0.26）d. 3 days after the operations, the UCVA≥0.5 was found in 88.9%(48/54) and ≥0.8 in 35.2% (19/54). 7 days after the operations, the UCVA≥0.5 was found in 100%(54/54) and ≥0.8 in 87.0% (47/54). 6 months after the operations the UCVA was equal with or better than the preoperative best corrected visual acuity (BCVA). 1, 3 and 6 months after the operations, corneal haze was found in 13 eyes（24.1%）, 7 eyes（13.0%） and 2 eyes（3.7%）respectively but it was below grade 2 and had no effect on visual acuity. Conclusion LASEK is a safe, effective, stable and predictable surgery for myopia.

Key words: Laser-assisted subepithelial keratomileusis, Myopia, Visual acuity, Corneal haze