JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY)

• Articles • Previous Articles     Next Articles

Effect of hypertonic saline on mucociliary clearance in patients with chronic rhinosinusitis

WANG De-hui,SUN Qiong,WANG Feng,YU Hua-peng,HU Li,ZANG Chao-ping   

  1. Department of Otorhinolaryngology,Eye and ENT Hospital of Fudan Univertisity,Shanhai 200031,China
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-04-24 Published:2007-04-24
  • Contact: WANG De-hui

PDF (PC)

1740

Abstract: Objective: To explore the effect of hypertonic saline on nasal mucociliary clearance in patients with chronic rhinosinusitis. Methods: The saccharin test was used to determine the mucociliary clearance before irrigation and after normal saline or hypertonic saline irrigation. On the following days, an alternative solution was used to repeat the treatment and retest the mucociliary clearance time. Results: The normal saccharin clearance time of patients with chronic rhinosinusitis was 19.62 minutes, and it changed to 17.74 and 13.22 minutes after the normal saline and hypertonic saline irrigation, respectively. Compared with the normal group, the mucociliary clearance was not significantly changed in the normal saline group (P＞0.05), but significantly decreased in the hypertonic saline group (P＜0.01). Conclusion: Hypertonic saline can significantly improve the nasal mucociliary clearance time, while normal saline has no such effect.

Key words: Hypertonic saline, Saccharin clearance test, Sinusitis

CLC Number: 

  • R765.21
[1] SONG Xiaoyu, ZHANG Yu, LI Chenglin, SONG Xicheng. Enhanced recovery after surgery for the treatment of chronic rhinosinusitis with nasal polyps [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2018, 32(5): 9-12.
[2] ZHANG Ruxiang, TIAN Hao, MA Youxiang. Computed tomography assessment of skull base height before endoscopic sinus surgery [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 75-77.
[3] WANG Chi, LIU Xing, KONG Lei, HONG Xinghe, NING Bo. Clinical efficacy of endoscopic plasma radiofrequency ablation in the treatment of adenoid hypertrophy and sinusitis in children and its effect on nasal mucociliary clearance [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 78-81.
[4] WU Xifu, KONG Weifeng, WANG Weihao, XU Huiqing, QI Min, YANG Qintai. Perioperative quality of life in patients with chronic rhinosinusitis with nasal polyps under enhanced recovery after surgery using QoR-15 [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2018, 32(5): 5-8.
[5] QIAO Shufen, YANG Feilun, WANG Zhenni, LI Xuezhong. Relationship between YKL-40 and chronic rhinosinusitis [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(4): 95-99.
[6] CHEN Wangxing, ZHAO Xue, LIU Yan, LIU Yue, JIN Chunshun. Psychological status of patients with deviated nasal septum or chronic sinusitis with nasal polyps [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(4): 24-27.
[7] Effect of short-term glucocorticoid inhalation on nasal symptoms and adrenocortical function in patients with eosinophilic chronic sinusitis accompanied by nasal polyps. Effect of short-term glucocorticoid inhalation on nasal symptoms and adrenocortical function in patients with eosinophilic chronic sinusitis accompanied by nasal polyps [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(4): 28-31.
[8] CHEN Ming, YU Xuefei. Opinions on the treatment of chronic rhinosinusitis with allergic rhinitis [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(3): 18-22.
[9] LOU Hongfei, WANG Chengshuo. Progress in classification of chronic sinusitis [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(3): 10-13.
[10] LI Huabin, LAI Yuting. Pathogenesis, diagnosis, and treatment of chronic rhinosinusitis [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(3): 4-9.
[11] ZHANG Guimin, LIN Peng. Endotype of chronic rhinosinusitis: from basic to clinical research [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(3): 14-17.
[12] ZHANG Wei, ZENG Yuhan, YU Xiansong. Changes in nasal secretion of ECP, EGF and IL-6 in patients with chronic sinusitis before and after endoscopic sinus surgery and their clinical significance [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(3): 63-67.
[13] LI Ying. Syndrome differentiation of chronic sinusitis [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(3): 27-30.
[14] LI Hongmei, WANG Lan, GAO Zhaohui, WANG Ying, XUE Jinmei. The expression and significance of p-ERK2/ ERK2 in nasal polyps [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(3): 42-46.
[15] ZHANG Jie, GONG Qi. Clinical significance of eosinophils and neutrophils in blood and allergic reaction in patients with chronic rhinosinusitis [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(3): 54-57.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd