JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY)

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BAI Yong，LI Na，ZHANG Nian-kai   

  1. Department of Otorhinolaryngology & Head and Neck Surgery, Affiliated Hospital of Medical College of Qingdao University, Qingdao 266003, Shandong, China
  • Received:2006-08-31 Revised:1900-01-01 Online:2006-10-24 Published:2006-10-24
  • Contact: BAI Yong

Abstract: To observe the effect of Azithromycin on the epithelialization of nasal mucosal of chronic sinusitis after endoscopic sinus surgery. Methods： From December 2004 to December 2005, 59 patients with chronic sinusitis and/or nasal polyp were treated with endoscopic surgery. One month after the operation, they were divided into two groups, and 37 patients were treated with cephamycin as a control group and 22 with Azithromycin as a experimental group. The course and the number of epithelialization were counted. Results： Within 6 months, epithelialization happened in 22126 days( average 51.1423±27.655 days) in control group, and in 1188 days( average 33.046±18.874 days) in experimental group, and the difference was statistically significant(t=2.624, P=0.006). Epithelialization happened in 28 cases in the control group and 22 cases in experimental group, and the difference was also statistically significant (χ2=4.573, P=0.033). Conclusion： Azithromycin is effective in accelerating the epithelialization of nasal mucosa after endoscopic sinus surgery.

Key words: chronic, Sinusitis, Surgical procedures, operative, Nasal mucosa

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