JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2016, Vol. 30 ›› Issue (2): 94-97.doi: 10.6040/j.issn.1673-3770.0.2015.372

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Clinical observation on the effects of three surgical methods for pterygium.

WANG Dan, WANG Rui, ZHANG Qiming, WANG Liwen   

  1. Department of Ophthalmology, Affiliated Hospital of Jianghan University(the Sixth Hospital of Wuhan City), Wuhan, 430015, Hubei, China
  • Received:2015-09-02 Online:2016-04-16 Published:2016-04-16

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Abstract: Objective To compare the therapeutic effects of simple pterygium excision, pterygium excision combined with free conjunctival flap transplantation and pterygium excision combined with autologous corneal limbus stem cell transplantation in the treatment of pterygium. Methods Totally 162 patients(186 eyes)were randomly divided into Group A, B and C. Group A were treated with simple pterygium excision, Group B with pterygium excision combined with free conjunctival flap transplantation, and Group C with pterygium excision combined with autologous corneal limbus stem cell transplantation. The recurrence rate, incidence of complications and change of tear function after surgeries were compared among the three groups. Result Group A was significantly lower than Group B and C in the cure rate, was higher than Group B and C in the incidence of complications and recurrence rate, and was longer than Group B and C in repair time(P<0.05). The incidence of complications, recurrence rate were lower and cure rate and repair time were better in Group C than those in Group B(P<0.05). The early postoperative tear films stability of Group B and C were better than that of Group A, with statistically significant difference(P<0.05). Conclusion Compared with single pterygium excision and pterygium excision combined with free conjunctival flap transplantation, pterygium excision combined with autologous corneal limbus stem cell transplantation is an effective method to treat pterygium,which can reduce the rate of complications, the recurrence,and improve tear function for patients with pterygium.

Key words: Pterygium, Conjunctival flap transfusion, Tear film, Autologous corneal limbus stem cell transplantation

CLC Number: 

  • R779.6
[1] Rezvan F, Hashemi H, Emamian M H, et al. The prevalence and determinants of pterygium and pinguecula in an urban population in Shahroud, Iran[J]. Acta Med Iran, 2012, 50(10): 689-696.
[2] 李兆瑞, 刘二华. 原发性翼状胬肉发病机制和治疗新进展[J]. 国际眼科杂志, 2012, 12(4): 660-663. LI Zhaorui, LIU Erhua. Research advancement in pathogenesis and therapy of primary pterygium[J]. Inter Eye Sci, 2012, 12(4): 660-663.
[3] Gulkilik G, Kocabora S, Taskapili M, et al. A new technique for pterygium excision: air-assisted dissection. Ophthalmologica[J]. 2006, 220(5): 307-310.
[4] Katirciolu Y A, Altiparmak U E, Duman S. Comparison of three methods for the treatment of pterygium: amniotic membrane graft, conjunctival autograft and conjunctival autograft plus mitomycin C[J]. Orbit,2007, 26(1): 5-13.
[5] 宋小平, 李育广, 危高生, 等. 两种术式治疗翼状胬肉疗效观察[J]. 实用中西医结合临床, 2012, 12(3): 51-52. SONG Xiaoping, LI Yuguang, WEI Gaosheng, et al. Observation on two kinds of surgical methods for treating pterygium[J]. Prac Clin J Integ Trad Chin West Med, 2012, 12(3): 51-52.
[6] 田瑾, 刘梅,刘孟军, 等. 自体角膜缘干细胞移植治疗翼状胬肉临床分析[J].陕西医学杂志, 2012, 41(1): 118-119. TIAN Jin, LIU Mei, LIU Mengjun, et al. Clinical analysis of autologous corneal limbus stem cell transplantation for treating pterygium[J]. Shaanxi Med J, 2012, 41(1): 118-119.
[7] 张秋玲,李建强,黄扬.自体角膜缘干细胞移植术治疗翼状胬肉疗效分析[J].吉林医学, 2013, 34(22): 4501-4502. ZHANG Qiuling, LI Jianqiang, HUANG Yang. Effect of autologous corneal limbus stem cell transplantation for treating pterygium[J]. Jilin Med J, 2013, 34(22): 4501-4502.
[8] 李绍军.角膜干细胞移植治疗翼状胬肉的疗效分析[J]. 国际眼科杂志, 2011, 11(2): 360-361. LI Shaojun. Corneal stem cell transplantation in the treatment of pterygium[J]. Inter Eye Sci, 2011, 11(2): 360-361.
[9] 邢怡桥, 但汉东, 李拓, 等. 自体角膜缘干细胞移植治疗翼状胬肉Meta分析[J]. 中国实用眼科杂志, 2013, 31(4): 433-437. XING Yiqiao, DAN Handong, LI Tuo, et al. A Meta-analysis of limbal autograft in treatment of pterygium[J]. Chin J Prac Ophthalmol, 2013, 31(4): 433-437.
[10] Esquenazi S. Autogenous lamellar scleral graft in the treatment of scleral melt after pterygium surgery[J]. Graefes Arch Clin Exp Ophthalm, 2007, 245(12):1869-1871.
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