Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2019, Vol. 33 ›› Issue (6): 68-71.doi: 10.6040/j.issn.1673-3770.0.2019.418

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Effects of anxiety and depression on nocturnal blood pressure fluctuation in patients with obstructive sleep apnea hypopnea syndrome

LI Xiao1, YUAN Ying1, LI Yanzhong2, WANG Yan2, YANG Ke1, SUN Yongqiang1, YU Xuemin1, WANG Ning1, WANG Lei1   

  1. Department of Otorhinolaryngology, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China
  • Published:2019-12-23

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Abstract: Objective To investigate the effects of anxiety and/or depression and cognitive decline on nocturnal blood pressure fluctuations in patients with obstructive sleep apnea hypopnea syndrome(OSAHS). Methods The study group included 81 patients with anxiety and/or depression and OSAHS, who were treated in Qilu Hospital of Shandong University(Qingdao)from August 2018 to May 2019, while 73 patients with OSAHS only were selected as controls. All patients were able to complete the Hamilton depression scale, self-rating anxiety scale, and self-rating depression scale evaluations and underwent overnight polysomnography(PSG)using SOMNOmedics V6. Simultaneously, PSG monitoring data were recorded. Patients were divided into three groups-mild, moderate, and severe-according to the apnea hypopnea index. Results The highest systolic blood pressure and systolic amplitude of the study group were significantly higher than those of the control group, and the differences were statistically significant. Conclusion Adverse psychological emotional states, such as anxiety and/or depression, and cognitive decline will affect the range of fluctuation of systolic blood pressure in patients with severe OSAHS. During sleep monitoring, it is necessary to pay close attention to changes in nocturnal blood pressure in patients with anxiety and/or depression and severe OSAHS to prevent cardiovascular complications.

Key words: Obstructive sleep apnea hypopnea syndrome, Anxiety and/or depression, Nocturnal fluctuation of blood pressure

CLC Number: 

  • R766.7
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