JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2017, Vol. 31 ›› Issue (1): 70-74.doi: 10.6040/j.issn.1673-3770.0.2016.533

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Obstructive sleep apnea and cancer: a review.

  

  1. Department of Respiratory, the Third Affiliated Hospital of Soochow University, Changzhou 213000, Jiangsu, China
  • Received:2016-12-28 Online:2017-02-16 Published:2017-02-16

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Abstract: Several studies have recently demonstrated that patients with obstructive sleep apnea(OSA)have a high prevalence of cancer and cancer-related mortality. A large number of animal experiments and clinical studies have further confirmed that OSA can be involved in tumorigenesis and progression. The mechanism may involve oxidative stress, systemic inflammation, sympathetic outflow, immune dysfunction, exosomes, hypoxia-inducible factor(HIF), and so on.

Key words: Neoplasms, Epidemiology, Mechanism, Sleep apnea, obstructive

CLC Number: 

  • R766.7
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