Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2023, Vol. 37 ›› Issue (4): 46-52.doi: 10.6040/j.issn.1673-3770.0.2022.551

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Correlation between the anxiety-depression state and idiopathic tinnitus prognosis

WU Bo1, HUANG Tiande1, YAN Bin1, CHEN Yi1, TANG Yong2   

  1. 1. Department of Otorhinolaryngology & Head and Neck Surgery, Sichuan Tianfu New Area People's Hospital, Chengdu 610213, Sichuan, China2. School of Clinical Medicine, Changchun University of Chinese Medicine, Changchun 130000, Jilin, China
  • Published:2023-07-27

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Abstract: Objective To study the anxiety and depression status of patients with idiopathic tinnitus and analyze the factors that may affect the prognosis of tinnitus. Methods The clinical data of 100 patients with idiopathic tinnitus were retrospectively analyzed. A uniform tinnitus treatment protocol was used. Patients were followed -up after 12 weeks of treatment to evaluate the efficacy and analyze the factors that may affect the prognosis of tinnitus. Results The effect of each scale after treatment was more than 0.50, and the difference was statistically significant(P<0.05). The GAD-7 score(Z=-6.482, P<0.001)and PHQ-9 score(Z=-6.070, P<0.001)were higher in the moderate-severe than in the mild tinnitus group. There were no statistically significant differences in the prognosis of tinnitus between the groups in terms of sex, age, side of tinnitus, loudness of tinnitus, frequency of tinnitus, degree of hearing loss, and duration of tinnitus disease(P>0.05). The pre-treatment THI score(OR=1.028, P=0.003), post-treatment improvement in anxiety(OR=5.637, P<0.001), post-treatment improvement in depression(OR=4.200, P=0.001), sleep improvement after treatment(OR=4.744, P=0.008)and clinical cure of tinnitus(OR=7.306, P<0.001)were independently associated with tinnitus prognosis. The multiple linear regression analysis results suggested that the pre-treatment THI score, clinical cure of tinnitus, and anxiety improvement after treatment positively correlated with tinnitus prognosis(all P<0.05). Conclusion Gender, age, side of tinnitus, loudness of tinnitus, frequency of tinnitus, degree of hearing loss, and tinnitus duration were not significantly associated with the prognosis. Conversely, the pre-treatment THI score, anxiety improvement after treatment, depression improvement after treatment, sleep improvement after treatment, and clinical cure of tinnitus were independently associated with tinnitus prognosis. The overall severity of tinnitus was positively associated with the anxiety-depression status. The anxiety-depression status of patients in the moderate-severe tinnitus group was more severe than that in the mild tinnitus group. Hence, clinical attention should be paid to the psychosocial status of patients with moderate-severe tinnitus.

Key words: Idiopathic Tinnitus, Anxiety, Depression, Somnipathy, Scale, Prognosis

CLC Number: 

  • 765.21
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