Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2026, Vol. 40 ›› Issue (3): 20-30.doi: 10.6040/j.issn.1673-3770.0.2023.524

• Original Article • Previous Articles     Next Articles

Meta analysis of clinical efficacy of cochlear implant in elderly patients with postlingual deafness

LI Shiyun1, XIE Yan2, PAN Jiayu1, CHEN Meixin1, LONG Dan1, ZHANG Chunlin1   

  1. 1. Department of Otolaryngology, the Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou, China2. School of Public Health, Zunyi Medical University, Zunyi 563000, Guizhou, China
  • Published:2026-05-22

PDF (PC)

11

Abstract: Objective Evaluate the impact of cochlear implant on hearing rehabilitation and quality of life in elderly patients with postlingual deafness. Methods Search was conducted in the PubMed, SinoMed, CNKI, WanFang data and VIP databases from 2000 to 2023. Studies on the postoperative rehabilitation effects of cochlear implantation in the elderly group(≥60 years old)and the young control group(<60 years old)with postlingual deafness, and last include literature that meets the standards and extract data. After all these steps, Meta analysis was conducted on the elderly group before and after surgery, as well as the elderly group and the year group control group, to evaluate the hearing rehabilitation and its impact on quality of life after cochlear implantation. Results A total of 14 literature were included in this study, and corresponding literature was included for Meta-analysis based on different analysis indicators. After cochlear implantation in elderly patients with postlingual deafness, compared to before surgery, in terms of word recognition rate ［SMD=2.20, 95%CI(1.73, 2.67)］, sentence recognition rate in quiet environment［SMD=1.63, 95%CI(1.37, 1.89)］, sentencerecognition rate in noisy environment ［MD=38.91, 95%CI(33.04, 44.78)］, and auditory performance ［MD=2.81, 95%CI(2.72, 2.91)］, there were significant improvements compared to preoperative results,and these differences are statistically significant(all P<0.001). The word recognition rate ［SMD=-0.59, 95%CI(-0.81, -0.36)］, auditory Performance ［MD=2.81, 95%CI(2.72, 2.91)］ and sentence recognition rate in a quiet environment ［SMD=-0.32, 95%CI(-0.57, -0.07)］ after cochlear implantation in elderly patients with postlingual deafness were lower than those in the young control group, and the differences were statistically significant(all P<0.05). However, there was no statistically significant difference in sentence recognition rate ［MD=-6.94, 95%CI(-14.60, 0.71)］ and pure tone hearing threshold test ［MD=1.35, 95%CI(-8.55, 11.25)］ in noisy environment compared to the control group patients. In terms of quality of life, there was no statistically significant difference in the total score of the Glasgow Benefit Scale ［MD=-3.12, 95%CI(-22.89, 16.66, P>0.05)］ between the elderly group and the control group. Conclusion Cochlear implantation can improve postoperative hearing ability in elderly patients with postlingual deafness. In terms of sentence recognition and quality of life scoring in noisy environments, similar postoperative rehabilitation effects can be achieved as young patients. However, the effectiveness of aural rehabilitation in terms of word recognition rate, sentence recognition rate in quiet environments, and auditory performance is lower than that of young patients.

Key words: Cochlear implant, Aural rehabilitation, Quality of life, Meta analysis

CLC Number: 

  • R764.9
[1] 高芬琦, 王林娥. 成人语后聋人工耳蜗植入的现状及研究进展[J]. 中国听力语言康复科学杂志, 2017, 15(1): 36-39. doi:10.3969/j.issn.1672-4933.2017.01.011 GAO Fenqi, WANG Line. The recent research progress for cochlear implantation in postlingually deaf adults[J]. Chinese Scientific Journal of Hearing and Speech Rehabilitation, 2017, 15(1): 36-39. doi:10.3969/j.issn.1672-4933.2017.01.011
[2] 赵春红, 刘玉和. 成人语后聋人工耳蜗植入诊疗进展[J]. 中国听力语言康复科学杂志, 2018, 16(1): 39-43. doi:10.3969/j.issn.1672-4933.2018.01.010 ZHAO Chunhong, LIU Yuhe. Progress in diagnosis and treatment of cochlear implantation in adults with postlingual hearing loss[J]. Chinese Scientific Journal of Hearing and Speech Rehabilitation, 2018, 16(1): 39-43. doi:10.3969/j.issn.1672-4933.2018.01.010
[3] Vermeire K, Brokx JPL, Wuyts FL, et al. Quality-of-life benefit from cochlear implantation in the elderly[J]. Otol Neurotol, 2005, 26(2): 188-195. doi:10.1097/00129492-200503000-00010
[4] Rostkowska J, Skarzynski PH, Kobosko J, et al. Health-related quality of life in adults with profound postlingual hearing loss before and after cochlear implantation[J]. Eur Arch Otorhinolaryngol, 2021, 278(9): 3393-3399. doi:10.1007/s00405-021-06866-7
[5] Schafer EC, Miller S, Manning J, et al. Meta-analysis of speech recognition outcomes in younger and older adults with cochlear implants[J]. Am J Audiol, 2021, 30(3): 481-496. doi:10.1044/2021_AJA-20-00141
[6] Andrade C. Mean difference, standardized mean difference(SMD), and their use in Meta-analysis: as simple as It Gets[J]. J Clin Psychiatry, 2020, 81(5): 20. doi: 10.4088/JCP.20f13681
[7] Zwolan TA, Henion K, Segel P, et al. The role of age on cochlear implant performance, use, and health utility: a multicenter clinical trial[J]. Otol Neurotol, 2014, 35(9): 1560-1568. doi:10.1097/MAO.0000000000000583
[8] Friedland DR, Runge-Samuelson C, Baig H, et al. Case-control analysis of cochlear implant performance in elderly patients[J]. Arch Otolaryngol Head Neck Surg,2010,136(5):432-438. doi:10.1001/archoto.2010.57
[9] Lee S, Park HJ, Cho HH, et al. Speech perception and auditory performance following cochlear implantation in elderly Koreans[J]. Ear Nose Throat J, 2017, 96(3): 112-118. doi:10.1177/014556131709600310
[10] Ghiselli S, Nedic S, Montino S, et al. Cochlear implantation in post-lingually deafened adults and elderly patients: analysis of audiometric and speech perception outcomes during the first year of use[J]. Acta Otorhinolaryngol Ital, 2016, 36(6): 513-519. doi:10.14639/0392-100X-1222
[11] Shew MA, Herzog JA, Kallogjeri D, et al. The Impact of Age on Noise Sensitivity in Cochlear Implant Recipients[J]. Otol Neurotol, 2022, 43(1):72-79. doi:10.1097/MAO.0000000000003385
[12] Roberts DS, Lin HW, Herrmann BS, et al. Differential cochlear implant outcomes in older adults[J]. Laryngoscope, 2013,123(8): 1952-1956. doi:10.1002/lary.23676
[13] Sorrentino T, Donati G, Nassif N, et al. Cognitive function and quality of life in older adult patients with cochlear implants[J]. Int J Audiol, 2020, 59(4): 316-322. doi:10.1080/14992027.2019.1696993
[14] Calvino M, Sánchez-Cuadrado I, Gavilán J, et al. Effect of cochlear implantation on cognitive decline and quality of life in younger and older adults with severe-to-profound hearing loss[J]. Eur Arch Otorhinolaryngol, 2022, 279(10): 4745-4759. doi:10.1007/s00405-022-07253-6
[15] 郑梦梦, 王凯, 严降雨, 等. 不同年龄成人语后聋患者人工耳蜗植入的疗效研究[J]. 中国耳鼻咽喉头颈外科, 2020, 27(02): 94-97. doi:10.16066/j.1672-7002.2020.02.010 ZHENG Mengmeng, WANG Kai, YAN Xiangyu, et al. Study on the efficacy of cochlear implantation in adult patients with postlingual deafness of different ages[J]. Chinese Archives of Otolaryngology-Head and Neck Surgery, 2020, 27(2): 94-97. doi:10.16066/j.1672-7002.2020.02.010
[16] Knopke S, Gräbel S, Förster-Ruhrmann U, et al. Impact of cochlear implantation on quality of life and mental comorbidity in patients aged 80 years[J]. Laryngoscope, 2016, 126(12): 2811-2816. doi:10.1002/lary.25993
[17] Issing C, Baumann U, Pantel J, et al. Cochlear Implant Therapy Improves the Quality of Life in Older Patients-A Prospective Evaluation Study[J]. Otol Neurotol, 2020, 41(9): 1214-1221. doi:10.1097/MAO.0000000000002741
[18] Knopke S, Häussler S, Gräbel S, et al. Age-dependent psychological factors influencing the outcome of cochlear implantation in elderly patients[J]. and, 2019, 40(4): e441-e453. doi:10.1097/MAO.0000000000002179
[19] Manrique-Huarte R, Calavia D, Huarte Irujo A, et al. Treatment for hearing loss among the elderly: auditory outcomes and impact on quality of life[J]. Audiol Neurootol, 2016, 21(Suppl 1): 29-35. doi:10.1159/000448352
[20] Völter C, Götze L, Haubitz I, et al. Benefits of cochlear implantation in middle-aged and older adults[J]. Clin Interv Aging, 2020, 15: 1555-1568. doi:10.2147/CIA.S255363
[21] 高芬琦, 王林娥, 王伟, 等. 植入年龄对成人语后聋患者人工耳蜗植入术后听觉言语康复效果的影响[J]. 听力学及言语疾病杂志, 2019, 27(4): 414-416. doi:10.3969/j.issn.1006-7299.2019.04.016 GAO Fenqi, WANG Line, WANG Wei, et al. The rehabil itative effect of implanted age on cochlear implants in adults with postl ingual deafness[J]. Journal of Audiology and Speech Pathology, 2019, 27(4): 414-416. doi:10.3969/j.issn.1006-7299.2019.04.016
[22] 中华耳鼻咽喉头颈外科杂志编辑委员会, 中华医学会耳鼻咽喉头颈外科学分会, 中国残疾人康复协会听力语言康复专业委员会. 人工耳蜗植入工作指南(2013)[J]. 中华耳鼻咽喉头颈外科杂志, 2014, 49(02): 89-95. doi: 10.3760/cma.j.issn.1673-0860.2014.02.001 Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association, Hearing and Language Rehabilitation Committee of China Association of Rehabilitation of Disabled Persons. Guideline of cochlear implant(2013)[J]. Chinese Journal of Otorhinolaryngology Head and Neck Surgery, 2014, 49(02): 89-95. doi: 10.3760/cma.j.issn.1673-0860.2014.02.001
[23] Chen DS, Clarrett DM, Li LS, et al. Cochlear implantation in older adults: long-term analysis of complications and device survival in a consecutive series[J]. and, 2013, 34(7): 1272-1277. doi:10.1097/MAO.0b013e3182936bb2
[24] Carlson ML, Lohse CM, Marinelli JP, et al. Perceptions surrounding cochlear implants among at-risk and qualifying older adults in the United States[J]. and, 2023, 44(10): 1021-1026. doi:10.1097/MAO.0000000000004041
[25] Zhao EE, Dornhoffer JR, Loftus C, et al. Association of patient-related factors with adult cochlear implant speech recognition outcomes: a meta-analysis[J]. JAMA Otolaryngol Head Neck Surg, 2020, 146(7): 613-620. doi:10.1001/jamaoto.2020.0662
[26] Völter C, Götze L, Dazert S, et al. Can cochlear implantation improve neurocognition in the aging population?[J]. Clin Interv Aging, 2018, 13: 701-712. doi:10.2147/CIA.S160517
[27] Chung J, Chueng K, Shipp D, et al. Unilateral multi-channel cochlear implantation results in significant improvement in quality of life[J]. Otol Neurotol, 2012, 33(4): 566-571. doi:10.1097/MAO.0b013e3182536dc2
[28] Aylward A, Murphy-Meyers M, Allen CM, et al. Frailty and quality of life after cochlear implantation in older adults[J]. Otolaryngol Head Neck Surg, 2022, 166(2): 350-356. doi:10.1177/01945998211004589
[29] Mosnier I, Vanier A, Bonnard D, et al. Long-term cognitive prognosis of profoundly deaf older adults after hearing rehabilitation using cochlear implants[J]. J Am Geriatr Soc, 2018, 66(8): 1553-1561. doi:10.1111/jgs.15445
[30] Aimoni C, Ciorba A, Hatzopoulos S, et al. Cochlear implants in subjects over age 65: quality of life and audiological outcomes[J]. Med Sci Monit, 2016, 22: 3035-3042. doi:10.12659/msm.896869
[31] Beyea JA, McMullen KP, Harris MS, et al. Cochlear implants in adults: effects of age and duration of deafness on speech recognition[J]. Otol Neurotol,2016,37(9):1238-1245. doi:10.1097/MAO.0000000000001162
[32] Atak HBO, Sennaroglu G, Sennaroglu L. Speech recognition and quality of life outcomes of adults with cochlear implants following a quarter-century of deafness: what should be the maximum duration?[J]. Eur Arch Otorhinolaryngol, 2023, 280(11): 4903-4913. doi:10.1007/s00405-023-08214-3
[33] Lin FR, Chien WW, Li L, et al. Cochlear implantation in older adults[J]. Medicine(Baltimore), 2012, 91(5): 229-241. doi:10.1097/MD.0b013e31826b145a
[34] Bourn SS, Goldstein MR, Morris SA, et al. Cochlear implant outcomes in the very elderly[J]. Am J Otolaryngol, 2022, 43(1): 103200. doi:10.1016/j.amjoto.2021.103200
[35] Ernst A, Basta D, Mittmann P, et al. Can hearing amplification improve presbyvestibulopathy and/or the risk-to-fall?[J]. Eur Arch Otorhinolaryngol, 2021, 278(8): 2689-2694. doi:10.1007/s00405-020-06414-9
[1] CHI Wenyue, LIN Ken, MA Jing, DU Yuling, GAO Yingqin, ZHOU Lijuan, ZHANG Hengying, ZHANG Tiesong. The impact of different language environments and parents' knowledge-attitude-practice on the auditory-verbal rehabilitation of children with cochlear implants [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2025, 39(1): 8-15.
[2] LI Xia, HOU Ran, WANG Liping. Bibliometric analysis based on Web of Science for nasal irrigation for nasal diseases in the last decade [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(2): 52-60.
[3] WANG Jiahui, LIU Xueqin. A global study on quality of life related to dry eye in the last ten years: bibliometrics and visualization analysis through VOSviewer and CiteSpace [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(2): 61-72.
[4] ZHANG Xi, DENG Qicheng, ZHANG Zhen, CHEN Yao, WANG Jingsong, ZHAO Rui, LIU Hai. Effect of nutritional support on postoperative pharyngeal fistula after laryngeal cancer surgery: a Meta-analysis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2023, 37(3): 51-59.
[5] FENG Yanyan, ZHANG Danxu, ZHANG Kangda, WANG Linyu, WANG Huanliang. Effect of great auricular nerve block on emergence delirium in children undergoing cochlear implantation [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2023, 37(1): 15-19.
[6] REN Jia, LÜ Dan, ZHANG Yin, SUN Jiali, MA Lan, ZHENG Yitao, YANG Jimin, YU Lingyu, LI Bo. Application of combining fiberoptic endoscopic evaluation of swallowing technology and swallowing quality of life scale in patients with dysphagia after chemoradiotherapy for nasopharyngeal carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(6): 83-88.
[7] NI Jingzi, WAN Wenjin,CHENG Lei. Research progress on health-related quality of life in allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(3): 110-115.
[8] ZHU Zhengru, ZHANG Xiaobing. Meta-analysis of the curative effect of traditional Chinese medicine decoction combined with conventional western medicine on allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(3): 281-289.
[9] BAI Lingling, WANG Hongxing, WANG Lichun. Effect of absorbable lacrimal plug combined with artificial tears on the treatment of moderate to severe dry eye and its impact on vision-related quality of life [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(2): 78-82.
[10] WANG Fei, LIU Yuying, XIAO Qiyi, DING Jian, GAO Shang, MAO Wei. A study on the associations between psychological factors and allergic rhinitis among residents [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(5): 28-31.
[11] XU Jianhui, LI Xin, CUN Jingjing, YE Fei. Effect of enhanced recovery after surgery in the perioperative period of endoscopic septoplasty [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(1): 21-24.
[12] JI Di, DENG Anchun. Meta-analysis of the effect of surgery for obstructive sleep apnea hypopnea syndrome on blood pressure [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(6): 92-98.
[13] Shujing HAN,Jie LU,Ping CHU,Lixing TANG,Huiwen ZHENG,Xiaojian YANG,Wei ZHANG,Pengpeng WANG,Jie ZHANG,Yongli GUO,Wentong GE. Meta analysis of the nasal cavity bacterial culture in chronic rhinosinusitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(5): 132-138.
[14] Kaili SUN,Xiaoyuan WU,Xu BIE,Xiuzhen SUN. Clinical analysis of cochlear implants in 16 patients with large vestibular aqueduct syndrome [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(5): 48-51.
[15] ZHANG Xiaoping, YANG Dengquan, WANG Shaoxin, HUANG Xiaoming. Effects of continuous out-of-hospital administration on the quality of life in patients with laryngeal cancer [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(4): 169-174.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd