山东大学耳鼻喉眼学报

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脑干听觉诱发电位对脑外伤后持续植物状态评价的意义

程友, 王秋萍,钱宇虹,郭梦和,王天友,李泽卿   

  1. 1.南京军区南京总医院耳鼻咽喉-头颈外科, 江苏 南京 210002;2.南方医科大学珠江医院耳鼻咽喉科,广东 广州 510282
  • 收稿日期:2006-07-02 修回日期:1900-01-01 出版日期:2006-08-24 发布日期:2006-08-24
  • 通讯作者: 李泽卿

Evaluation of brainstem auditory evoked potential for patients with severe traumatic brain injury in persistent vegetative state

CHENG You,WANG Qiu-ping,QIAN Yu-hong,GUO Meng-he,WANG Tian-you,LI Ze-qing   

  1. 1.Department of Otolaryngology & Head and Neck Surgery, Nanjing General Hospital of Nanjing Military Command, Nanjing 210002, Jiangsu, China; 2. Department of Otolaryngology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282,
  • Received:2006-07-02 Revised:1900-01-01 Online:2006-08-24 Published:2006-08-24
  • Contact: LI Ze-qing

摘要: 目的:通过脑干听觉诱发电位(brainstem auditory evoked potential, BAEP)评估颅脑外伤后持续植物状态(persistent vegetative state, PVS)患者的脑干功能。方法:对25例(50耳)PVS患者行BAEP检测,并与对照组行单因素方差分析。结果:PVS患者的BAEP异常率为80%。其改变复杂多样,主要表现为ⅠV各波的异常或分化不良,甚至波形缺如;Ⅰ、Ⅲ、Ⅴ波潜伏期(peak latency, PL)延长,IV波间潜伏期(Interpeak latency, IPL)延长,双侧V波潜伏期的耳间差(interaural latency difference, ILD)增大;ⅢV与ⅠⅢ波IPL之比大于1。结论:PVS患者的BAEP结果呈多样性改变,反映了患者植物状态下存在不同程度的脑干损害,为其诊疗及预后判断提供了可靠的依据。

关键词: 脑干听觉诱发电位, 颅脑损伤, 持续植物状态

Abstract: To study the value of brainstem auditory evoked potential (BAEP) in evaluating the function of brainstem in patients with severe traumatic brain injury in persistent vegetative state(PVS). Methods: Twentyfive patients with severe traumatic brain injury in PVS were examined by BAEP and the data were compared with normal. Results: The abnormal rate of BAEP was 80%(20/25). The alterations included delay of peak latency of I, Ⅲ, and V waves, prolongation of interpeak latency between wave I and V, increase of interaural latency difference of wave V and greater interpeak latency between ⅢV and IⅢ. Conclusion: BAEP can be used to evaluate the function of brainstem in patients with severe traumatic brain injury in PVS and provide evidences for prognosis.

Key words: Traumatic brain injury, Brainstem auditory evoked potential, Persistent vegetative state

[1] 郑立友1,李学军2. 耳鼻喉颌面伤合并颅脑损伤500例[J]. 山东大学耳鼻喉眼学报, 2014, 28(1): 59-61.
[2] 康宏建,李晓红,王保安,周 涛 . 重型颅脑损伤患者行气管切开术的意义[J]. 山东大学耳鼻喉眼学报, 2007, 21(3): 234-236 .
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