低温射频消融术治疗阻塞性睡眠呼吸暂停低通气综合征

山东大学耳鼻喉眼学报

低温射频消融术治疗阻塞性睡眠呼吸暂停低通气综合征

万汉锋，金建新，高金建，凡启军，刘学军，黄加云，陈波蓓

温州医学院附属第二医院耳鼻咽喉科，浙江温州 325027

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2007-06-24 发布日期:2007-06-24
通讯作者: 万汉锋

Temperature-controlled radio-frequency ablation in treatment of obstrustive sleep apnea hypopnea syndrome

WAN Han-feng, JIN Jian-xin, GAO Jin-jian， FAN Qi-jun, LIU Xue-jun, HUANG Jia-yun, CHEN bo-bei

Department of Otorhinolaryngology, Second Affiliated Hospital of Wenzhou Medical College,Wenzhou 325027, Zhejiang, China

Received:1900-01-01 Revised:1900-01-01 Online:2007-06-24 Published:2007-06-24
Contact: WAN Han-feng

摘要/Abstract

摘要： 目的：探讨低温射频消融术（temperature-controlled radiofrequency ablation，TCRF）治疗阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome，OSAHS) 的疗效和手术前后生活质量的变化。方法：对50例OSAHS 患者行TCRF治疗，比较治疗前后呼吸暂停低通气指数(apnea hypopnea index，AHI)、最低血氧饱和度(lowest arterial oxygeon saturation，LSaO2)、Epworth嗜睡评分(Epworth Sleepiness Scale，ESS) 和Calgary生活质量指数（Calgary Sleep Apnea Quality of Life Index，SAQLI），从主、客观方面对TCRF治疗OSAHS进行疗效评价。结果：术后6个月复查多导睡眠监测（polysomnography，PSG），50例患者中总有效43例，其中治愈19例，显效18例，有效6例，无效7例，总有效率86.0%。手术前后AHI平均值分别为45.20+20.50和26.50+30.15, LSaO2平均值分别为0.70+0.24和0.83+0.10。Epworth嗜睡程度评分由术前9.4+5.2下降至术后4.0+3.3，SAQLI总分从术前3.9+1.0提高到术后4.7+1.1，差异均有统计学意义（P值均＜0.05）。结论：TCRF是治疗OSAHS的有效方法，可提高OSAHS患者的生活质量。

关键词: 睡眠呼吸暂停低通气综合征, 阻塞性, 等离子射频, 消融, 生活质量

Abstract: Objective: To determine the efficacy of temperature－controlled radio-frequency ablation (TCFR) for obstructive sleep apnea hypopnea syndrome (OSAHS) in adult. Methods: Some objective and subjective indexes of fifty patients with OSAHS were determined before and after TCRF treatment. A full-night polysomnography examination was performed on all patients. The Epworth sleepiness scale (ESS) and the Calgary sleep apnea quality of life index (SAQLI) were assessed before and six months after operation. Results: Of them, 19 cases were cured, 18 cases were significantly improved, 16 cases were improved, and 7 cases were not improved. The mean apnea hypopnea index （AHI） decreased from（45.2+20.5）/h to (26.5+30.2)/h and the mean lowest arterial oxygen saturation (LSaO2) increased from(0.7+0.1) to (0.8+0.1). The ESS decreased from (9.4+5.2) to (4.0+3.3) and the SAQLI increased from(3.8+1.0) to (4.8+1.1). All the above differences were significant (P＜0.05). Conclusion: TCFR is an effective treatment for OSAHS and can improve the health-related quality of life.

Key words: Sleep apnea hypopnea syndrome, obstructive, Plasma radio-frequency, Ablation, Health-related quality of life

中图分类号:

R766.7

万汉锋,金建新,高金建,凡启军,刘学军,黄加云,陈波蓓 . 低温射频消融术治疗阻塞性睡眠呼吸暂停低通气综合征[J]. 山东大学耳鼻喉眼学报, 2007, 21(3): 229-231 .

WAN Han-feng,JIN Jian-xin,GAO Jin-jian,FAN Qi-jun,LIU Xue-jun,HUANG Jia-yun,CHEN bo-bei . Temperature-controlled radio-frequency ablation in treatment of obstrustive sleep apnea hypopnea syndrome[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2007, 21(3): 229-231 .

参考文献

相关文章 15

[1]	刘大炜,张宇,李成林,陈秀梅,宋西成. 加速康复外科在儿童OSAS围手术期中的应用[J]. 山东大学耳鼻喉眼学报, 2018, 32(5): 19-22.
[2]	吴喜福, 孔维封, 王玮豪, 徐惠清, 戚敏, 杨钦泰. QoR-15在加速康复外科改善慢性鼻-鼻窦炎伴鼻息肉围手术期生活质量评估中的应用[J]. 山东大学耳鼻喉眼学报, 2018, 32(5): 5-8.
[3]	王驰,刘星,孔磊,洪兴和,宁博. 鼻内镜下等离子射频消融术对合并鼻窦炎的小儿腺样体肥大患者疗效及鼻腔黏膜纤毛清除功能的影响[J]. 山东大学耳鼻喉眼学报, 2018, 32(5): 78-81.
[4]	吕旭琴,万文锦. 阻塞性睡眠呼吸暂停低通气综合征合并高血糖患者的围手术期血糖管理[J]. 山东大学耳鼻喉眼学报, 2018, 32(4): 100-104.
[5]	沈翎,林宗通,林兴,杨中婕. 儿童阻塞性睡眠呼吸暂停低通气综合征危险因素的[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 25-29.
[6]	李延忠,张泰. 关于儿童阻塞性睡眠呼吸暂停低通气综合征我们面临的问题[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 1-5.
[7]	张会芳,杨红珍. 经鼻持续气道正压通气对阻塞性睡眠呼吸暂停低通气[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 48-51.
[8]	许志飞,倪鑫. 重视阻塞性睡眠呼吸暂停低通气综合征儿童腺样体[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 9-13.
[9]	王岩,师晓丽. 变态反应与儿童OSAHS的关系[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 14-18.
[10]	杨微,郑莉,许志飞. 中重度阻塞性睡眠呼吸暂停低通气综合征儿童无创正压[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 19-24.
[11]	仇书要,刘大波,钟建文,杨李强. 儿童阻塞性睡眠呼吸暂停低通气综合征等离子[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 34-37.
[12]	钟建文,刘大波,罗向前,黄振云,仇书要,程超,杨李强,易新华,曾锦鸿. 可穿戴设备在儿童阻塞性睡眠呼吸暂停诊断中的应用[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 30-33.
[13]	李浩,李延忠,王岩. HIF-1α、VEGF在阻塞性睡眠呼吸暂停低通气综合征患者[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 43-47.
[14]	龚齐,张劼,赵屏屏. 鼻腔扩容术对慢性鼻-鼻窦炎伴睡眠呼吸暂停[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 52-55.
[15]	王红梅,李连贺. 神经心理量表联合事件相关电位对中、重度阻塞性睡眠呼吸[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 56-61.

多维度评价

Viewed

Full text

Abstract

Cited

Shared

Discussed