手术治疗脑垂体瘤舌体肥大所致重症阻塞性睡眠呼吸暂停低通气综合征3例

山东大学耳鼻喉眼学报

手术治疗脑垂体瘤舌体肥大所致重症阻塞性睡眠呼吸暂停低通气综合征3例

张庆泉，宋西成，王艳

青岛大学医学院附属烟台毓璜顶医院耳鼻咽喉-头颈外科，山东烟台 264000

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2008-08-16 发布日期:2008-08-16
通讯作者: 张庆泉

Hypophyseoma with hypertrophic corpus linguae induced severe obstructive
sleep apnea hypopnea syndrome in 3 cases

ZHANG Qing-quan, SONG Xi-cheng, WANG Yan

Department of Otolaryngology & Head and Neck Surgery, Yuhuangding Hospital, Medical College of Qingdao University, Yantai 264000, Shandong, China

Received:1900-01-01 Revised:1900-01-01 Online:2008-08-16 Published:2008-08-16
Contact: ZHANG Qing-quan

摘要/Abstract

摘要：

目的〓〖HTK〗探讨手术治疗脑垂体瘤舌体肥大所致重症阻塞性睡眠呼吸暂停低通气综合征（OSAHS）的疗效。〖HTW〗方法〓〖HTK〗对3例因为脑垂体瘤舌体肥大所致重症阻塞性睡眠呼吸暂停低通气综合征的患者，在全身麻醉气管切开下行悬雍垂腭咽成型术(UPPP)，联合颈外进路舌根舌体中线部分切除术。〖HTW〗结果〓〖HTK〗手术后2例患者顺利痊愈，1例手术后发生颈部间隙感染，经过引流换药，抗生素治疗，于术后第11天伤口愈合。3例患者经过1～3年的随访观察，患者自我感觉良好，白天无嗜睡现象，精力充沛；6个月、1年的睡眠监测显示，有效率达到100%。〖HTW〗结论〓〖HTK〗对因为脑垂体瘤舌体肥大所致重症阻塞性睡眠呼吸暂停低通气综合征的患者，根据实际病情，在术前或术后行悬雍垂腭咽成型术联合颈外进路舌根舌体舌骨手术，解决患者的腭咽和舌咽平面的阻塞问题。

关键词:

脑垂体瘤, 舌体肥大, 睡眠呼吸暂停, 阻塞性, 悬雍垂腭咽成型术, 外科手术

Abstract:

Objective〓〖WTBZ〗To explore the surgical effects of severe obstructive sleep apnea hypopnea syndrome (OSAHS) induced by hypophyseoma with hypertrophic corpus linguae. 〖WTHZ〗Method〓〖WTBZ〗3 cases were treated with uvulopalatopharyngolasty (UPPP) in combination with partial radix linguae and corpus linguae median line resection via the extro-neck approach. 〖WTHZ〗Results〓〖WTBZ〗2 cases were healed and 1 case suffered from infection in the neck inter-space which was healed after draining, dressing change and antibiotics administration on day 11. Followed up from six months to three years, 3 cases felt well, had no somnolence in daytime, and the somnus monitoring on the 6th and 12th showed that the response rate was 100%. 〖WTHZ〗Conclusions〓〖WTBZ〗Uvulopalatopharyngolasty (UPPP) in combination with radix linguae, corpus linguae and lingual bone operation via the extro-cervical approach is effective for solving obstructions in the palatopharygeum and glossopharyngeum planes for severe obstructive sleep apnea hypopnea syndrome (OSAHS) induced by hypophyseoma with hypertrophic corpus linguae.

Key words: Hypertrophic Corpus Linguae, Sleep apnea,

Hypophyseoma, obstructive, Uvulopalatopharyngolasty, Surgical procedures, operative

中图分类号:

R766.7

张庆泉,宋西成,王艳 . 手术治疗脑垂体瘤舌体肥大所致重症阻塞性睡眠呼吸暂停低通气综合征3例[J]. 山东大学耳鼻喉眼学报, 2008, 22(4): 293-295 .

ZHANG Qing-quan,SONG Xi-cheng,WANG Yan .

Hypophyseoma with hypertrophic corpus linguae induced severe obstructive
sleep apnea hypopnea syndrome in 3 cases

[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(4): 293-295 .

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