山东大学耳鼻喉眼学报 ›› 2012, Vol. 26 ›› Issue (1): 55-57.

• 论文 • 上一篇    下一篇

扁桃体滤泡树突状细胞肉瘤1例及文献复习

蔡智,郑世信,高重阳   

  1. 北京大学深圳医院耳鼻喉科, 广东  深圳  518036
  • 收稿日期:2011-06-10 出版日期:2012-02-16 发布日期:2012-02-16
  • 通讯作者: 郑世信,主任医师。 Email: zhengsx123@yahoo.com.cn
  • 作者简介:蔡智,主治医师,硕士研究生。

Follicular Dendritic Cell Sarcoma of Tonsil: a case report and review

CAI Zhi, ZHENG Shi-xin, GAO Chong-yang   

  1.  Department Of Otorhinolaryngology, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong, China
  • Received:2011-06-10 Online:2012-02-16 Published:2012-02-16

摘要:

目的   探讨扁桃体滤泡树突状细胞肉瘤的临床特点和病理特点,提高诊断、治疗的准确性。方法   回顾1例扁桃体滤泡树突状细胞肉瘤患者的病历资料,其治疗首选单纯扁桃体扩大切除术,术后1年颈部淋巴结转移,再次行双侧颈部选择性颈廓清术和术后放疗。总结病程资料,分析其临床特点,研究随访结果,复习相关文献。结果   随访5年,患者无瘤生存,咽喉无功能损失。结论   扁桃体滤泡状细胞肉瘤罕见,临床易误诊,诊断主要依据为病理加免疫组化检查,单纯手术治疗后有一定复发率。治疗首选手术,根据肿瘤累及范围界定放疗与否。

关键词: 扁桃体; 肉瘤; 滤泡树突状细胞肉瘤; 免疫组化; 超微结构

Abstract:

Objective   To investigate the clinical and pathologic characteristics of follicular dendritic cell sarcoma (FDCS) of tonsil to improve the diagnosis and treatment. Methods   The histopathological, immunohistochemical, clinical characteristics and treatment of a tonsil FDCS case was reviewed. One year after the extended tonsillectomy, the FDCS recurred and were further treated with radical neck dissection and postoperative radiotherapy. Related literature were reviewed. Results   The patient were followed up for 5 years without recurrence and lost function. Conclusions   The FDCS of tonsil is rare and often misdiagnosed  The diagnosis is based on the histopathology and immunohistochemistry. Recurrence were reported after the surgery. We recommend the primary treatment of FDCS of tonsil is surgery. Postoperative radiotherapy can be performed depending on the tumor extension and size.

Key words: Tonsil; Sarcoma; Follicular dendritic cell sarcoma; Immunohistochemistry; Ultrastructure

中图分类号: 

  • R766.49
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