山东大学耳鼻喉眼学报 ›› 2012, Vol. 26 ›› Issue (5): 66-67.

• 论著 • 上一篇    下一篇

低温等离子治疗喉损伤性肉芽肿9例

何本超,李健勇,颜风波,郑志刚   

  1. 天门市第一人民医院耳鼻咽喉头颈外科, 湖北 天门  431700
  • 收稿日期:2012-04-01 发布日期:2012-10-16
  • 作者简介:何本超,副主任医师。E-mail:hebenchao@126.com

Laryngeal injury granuloma treated by low temperature plasma ablation ( 9 cases report)

HE Ben-chao, LI Jian-yong, YAN Feng-bo, ZHENG Zhi-gang   

  1. Department of OtolaryngologyHead & Neck Surgery, Tianmen First Hospital, Tianmen 431700, Hubei, China
  • Received:2012-04-01 Published:2012-10-16

摘要:

目的    研究提高喉损伤性肉芽肿手术治疗效果的新方法。方法    9例喉损伤性肉芽肿患者中男2例,女7例;22~65岁,平均45岁; 9例患者就诊前1~3个月均有气管内插管史;经抗炎、禁声、雾化吸入治疗1~2月后无好转。2例尚有呼吸困难。在支撑喉镜下导入显微镜调整焦距,充分显露喉腔病变,开启流量泵和低温等离子射频消融系统,连接喉用7.0刀头,用脚踏板控制刀头,将等离子刀头置于肉芽肿表面,从上至下消融肉芽肿,直至肉芽肿基底,尽可能避免损伤周围黏膜。术后应用地塞米松及庆大霉素雾化吸入1周。结果    9例患者均一次手术成功,手术后肉芽肿复发1例,复发部位为对侧,经再次手术,未再复发。8例随访3个月~2年,未见复发,1例失访。病理检查证实,切取的肉芽组织表现为鳞状上皮黏膜慢性炎性反应,并有少量炎性细胞浸润。结论    低温等离子射频消融术治疗喉损伤性肉芽肿,为喉损伤性肉芽肿提供了一种安全、有效、微创的理想治疗术式,可避免术后复发。

关键词: 低温等离子;喉损伤性肉芽肿

Abstract:

Objective    To explore the new surgical technique to improve the treatment of laryngeal injury granuloma. Methods    Nine cases of laryngeal injury granuloma, including two males and seven females(mean 45 yr; range: 22-65 yrs old),were enrolled. All the patients underwent endotracheal intubation 1 to 3 months ago and no improvement were noted after 1-2 months of treatment, such as anti-inflammation, voice rest, or atomizing inhalation therapy. Two cases showed breathing difficulty. With microscope and suspension laryngoscope, radiofrequency ablation system  was applied to clear the granuloma from the top to the bottom without damages to the surrounding mucosa. After the surgery, atomizing inhalation of dexamethasone and gentamicin lasted for 1 week. Results    All the nine patients recovered well with only one relapse on the contralateral side, which was removed again in the second operation. Eight patients were followed up for 3 months to 2 years without recurrence. Pathological examination confirmed that the granulation tissue was squamous mucosa with chronic inflammatory response. Conclusion    Radiofrequency ablation is a safe, effective and minimally invasive method to treat laryngeal injury granuloma, without the  recurrence.

中图分类号: 

  • R767.1
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