山东大学耳鼻喉眼学报 ›› 2015, Vol. 29 ›› Issue (6): 49-51.doi: 10.6040/j.issn.1673-3770.0.2015.195

• 论著 • 上一篇    下一篇

声门上区喉淀粉样变3例并文献复习

陈乌娜, 高兴强   

  1. 厦门大学附属第一医院耳鼻咽喉头颈外科, 福建 厦门 361003
  • 收稿日期:2015-05-21 出版日期:2015-12-16 发布日期:2015-12-16
  • 通讯作者: 高兴强. E-mail:xingqiang7211@aliyun.com E-mail:xingqiang7211@aliyun.com
  • 作者简介:陈乌娜. E-mail:wuna80@sina.com

Clinical analysis of laryngeal amyloidosis in supragolttic portion: report of 3 cases and literature review

CHEN Wu na, GAO Xingqiang   

  1. Department of Otorhinolaryngology & Head and Neck Surgery, First Affiliated Hospital of Xiamen University, Xiamen 361003, Fujian, China
  • Received:2015-05-21 Online:2015-12-16 Published:2015-12-16

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摘要： 目的 探讨临床上易误诊为恶性肿瘤的声门上区喉淀粉样变的临床特点及诊治措施.方法 对3例声门上区喉淀粉样变患者行喉显微镜下CO2激光辅助喉部病变切除术,并对临床资料进行分析.结果 3例患者均经喉显微镜CO2激光手术治愈,术后随访1~2年,未复发.结论 喉淀粉样变临床表现缺乏特异性,但病理切片刚果红染色阳性可确诊本病;喉显微镜CO2激光手术是有效的喉淀粉样变治疗手段.

关键词: 喉淀粉样变, 刚果红染色, 二氧化碳激光手术

Abstract: Objective To explore the clinical characteristics and treatment of laryngeal amyloidosis (LA) likely to be misdiagnosed as laryngeal malignancy in supragolttic portion. Methods The three patients with LA in supragolttic portion received carbon dioxide (CO2) laser operation with microscopic laryngoscopy to remove the lesions. Relevant clinical data were analyzed. Results All patients recovered clinically. During the follow-up of one to two years, no recurrence occurred. Conclusion LA shows no specific clinical manifestation, whereas it can be confirmed by positive reaction of Congo red staining of pathological section. CO2 laser operation with microscopic laryngoscopy is effective in treating LA.

Key words: Laryngeal amyloidosis, Congo red staining, Carbon dioxide laser operation

中图分类号: 

  • R767.1
[1] 黄选兆, 汪吉宝. 实用耳鼻咽喉科学[M]. 北京: 人民卫生出版社, 1998: 547.
[2] Penner C R, Muller S. Head and neck amyloidosis: a clinicopathologic study of 15 cases[J]. Oral Oncol, 2006, 42(4):421-429.
[3] Thompson L D, Deringer G A, Wenig B M. Amyloidosis of the larynx: a clinicopathologic study of 11 cases[J]. Mod Pathol, 2000, 13(5):528-535.
[4] Alaani A, Warfield A T, Pracy J P. Management of laryngeal amyloidosis[J]. J Laryngol Otol, 2004, 118(4):279-283.
[5] 孔维佳. 耳鼻咽喉头颈外科学[M]. 2版. 北京: 人民卫生出版社, 2011: 468-469.
[6] Pribtikin E, Friedman O, O Hara B, et al. Amyloidosis of the upper aerodigestive tract[J]. Laryngoscope, 2003, 113(12):2095-2101.
[7] Gean-Marton A D, Kirsch C F, Vezina L G, et al. Focal amyloidosis of the head and neck: evaluation with the CT and MR imaging[J]. Radiology, 1991, 181(2):521-525.
[8] 杨登法, 姜亿一, 傅钢泽, 等. 多层螺旋CT及后处理技术在喉癌及下咽癌侵犯中的诊断价值[J]. 温州医科大学学报. 2014, 44(2):122-126. YANG Dengfa, JIANG Yiyi, FU Gangze, et al. The diagnostic value of multi-slice helical CT and image post-progressing technique in laryngeal and hypopharyngeal carcinoma[J]. J Wenzhou Med Univ, 2014, 44(2):122-126.
[9] 王洪伟, 张修石, 周洋, 等. MRI在喉癌术前分期中的临床应用价值[J]. 现代生物医学进展, 2015, 15(2):265-269. WANG Hongwei, ZHANG Xiushi, ZHOU Yang, et al. The clinical application value of MRI in the preoperative staging of laryngeal carcinoma[J]. Prog Mod Biomed, 2015, 15(2):265-269.
[10] Kennedy T L, Patel N M. Surgical management of localized amyloidosis[J]. Laryngoscope, 2000, 110(6):918-923.
[11] Ma L, Bandarchi B, Sasaki C, et al. Primary localized laryngeal amyloidosis: report of 3 cases with long-term follow-up and review of the literature[J]. Arch Pathol Lab Med, 2005, 129(2):215-218.
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