山东大学耳鼻喉眼学报 ›› 2017, Vol. 31 ›› Issue (6): 87-91.doi: 10.6040/j.issn.1673-3770.0.2017.242

• 综述 • 上一篇    下一篇

儿童上气道咳嗽综合征临床诊疗现状

敬尚林   

  1. 柳州市妇幼保健院耳鼻咽喉科, 广西 柳州 545001
  • 收稿日期:2017-06-01 出版日期:2017-12-16 发布日期:2017-12-16
  • 通讯作者: 敬尚林. E-mail:jshl9951@126.com
  • 基金资助:
    广西卫生和计划生育委员会自筹经费科研课题(Z2016532)

Diagnosis and treatment of upper airway cough syndrome in children.

JING Shanglin.   

  1. Department of Otolaryngology, Liuzhou Women and Childrens Hospital, Liuzhou 545001, Guangxi, China
  • Received:2017-06-01 Online:2017-12-16 Published:2017-12-16

摘要: 儿童上气道咳嗽综合征(UACS)是临床较为常见的慢性疾病,是引起儿童慢性咳嗽的主要原因之一。由于病因复杂,发病机制尚不明确,病症、病理又牵涉儿科、耳鼻咽喉科、呼吸科及免疫科等多个学科,因此应加强科室相互合作。针对儿童UACS的流行病学状况、发病机制的最新研究、诊疗指南和治疗方案的最新进展进行综述,并对今后规范、科学、有效地诊治儿童UACS提出了新的思路和方法。

关键词: 上气道咳嗽综合征, 诊断, 儿童, 治疗

Abstract: The upper airway cough syndrome(UACS)is a chronic disease commonly observed in pediatric clinics. Its pathogenesis is not clear and involves pediatric, otorhinolaryngology, respiratory, immunology, and other disciplines. In this paper, we present a comprehensive review of the recent advances in the epidemiology, pathogenesis, diagnosis, and treatment of UACS in children; we also put forth new ideas and methods for the diagnosis and treatment of UACS of the same.

Key words: Treatment, Child, Upper airway cough syndrome, Diagnosis

中图分类号: 

  • R725.6
[1] Haque RA, Usmani OS, Barnes PJ. Chronic idiopathic cough: a discrete clinical entity[J]. Chest, 2005, 127(5):1710-1713.
[2] 中国儿童慢性咳嗽病因构成比研究协作组. 儿童慢性咳嗽的病因及治疗[J]. 中华儿科杂志, 2012, 50(2):83-91. Clinical Research Coordination Group of the Causes Constituents Ratio of Chronic Cough in Chinese Children. Prospective multicenter clinical study on the causes constituents ratio of chronic cough in Chinese children[J]. Chin J Ped, 2012, 50(2):83-91.
[3] Morice AH, Fontana GA, Sovijarvi AR, et al. The diagnosis and management of chronic cough[J]. Eur Respir J, 2004, 24(3): 481-492.
[4] 雉本忠市,吉田璺.小完呼吸器病翠Ⅱ//小林登.新小兄罾睾大系9B[M]. 东京:中山书店株式会社,1980:35-39.
[5] 张正霞,张海邻,张维溪.儿童副鼻窦支气管炎治疗方案探讨[J]. 临床儿科杂志,2007, 25(6): 448-450. ZHANG Zhengxia, ZHANG Hailing, ZHANG Weixi. Evaluation of two treatments in childhood sinobronchitis[J]. J Clin Ped, 2007, 25(6):448-450.
[6] 中华医学会儿科学分会呼吸学组,中华儿科杂志编辑委员会.儿童慢性咳嗽诊断与治疗指南(试行)[J]. 中华儿科杂志, 2008, 46(2):104-107. The Subspecialty Group of Respiratory Diseases, The Society of Pediatrics, Chinese Medical Association, The Editorial Board,Chinese Journal of Pediatrics. Guideline for diagnosis and treatment of chronic cough in pediatrics[J]. Chin J Ped, 2008, 46(2):104-107.
[7] Klossek JM, Annesi Maesano I, Pribil C, et al. INSTANT:national survey of allergic rhinitis in a French adult population based sample[J]. Press Med, 2009, 3(8):1220-1229.
[8] 董兆华,隋萍.枣庄市中地区儿童上气道咳嗽综合征374例临床研究[J]. 基层医学论坛,2013,16(28): 3721-3723.
[9] 邓文学.儿童慢性上气道咳嗽综合征的病因及诊断分析[J]. 实用心脑肺血管病杂志, 2013, 21(2):83-84. DENG Wenxue. Causes and diagnosis analysis of chronic upper airway cough syndrome in children[J]. Pract J Card Cereb Pneumal Vascular Dis, 2013, 21(2):83-84.
[10] 喻宁芬,于力,翁志媛,等.儿童慢性上气道咳嗽综合征病因及诊断方法探讨[J]. 临床和实验医学杂志, 2008,7(1):45-46. YU Ningfen, YU Li, WENG Zhiyuan, et al. Clinical research of causes and diagnosis of chronic upper airway cough syndrome in children[J]. J Clin Exper Med, 2008, 7(1):45-46.
[11] 乔在霞, 崔振泽. 儿童上气道咳嗽综合征的临床研究[D]. 大连:大连医科大学, 2013:1-35.
[12] 余莉, 徐镶怀, 吕寒静, 等.上气道咳嗽综合征的研究新进展[J]. 中国呼吸与危重监护杂志, 2014, 13(5):526-530.
[13] 焦路燕,曹玲. 儿童上气道咳嗽综合征[J]. 中国实用儿科杂志, 2016, 31(3):179-182.
[14] Millqvist E. The airway sensory hyperreactivity syndrome[J]. Pulm Pharmacol Ther, 2011, 24(3):263-266.
[15] 中华医学会儿科学分会呼吸学组,中华儿科杂志编辑委员会. 儿童慢性咳嗽诊断与治疗指南(试行)[J]. 中华儿科杂志,2008, 46(10):755-756. The Subspecialty Group of Respiratory Diseases, The Society of Pediatrics, Chinese Medical Association, The Editorial Board, Chinese Journal of Pediatrics. Guideline for diagnosis and treatment of chronic cough in pediatrics[J]. Chin J Ped, 2008, 46(10):755-756.
[16] 陈霞萍. 非索非那定联合孟鲁司特治疗儿童上气道咳嗽综合征疗效观察[J]. 中国药师, 2013, 16(5):729-730.
[17] 刘字, 徐夏, 郑云开, 等. 吸入布地奈德治疗儿童上气道咳嗽综合征的近期疗效观察[J]. 中国眼耳鼻喉科杂志, 2013, 13(3):149-151. LIU Zi, XU Xia, ZHENG Yunkai, et al. Short-term therapeutic effect of budesonide inhalation on children with upper airway cough syndrome[J]. Chin J Ophthalmol Otorhinolaryngol, 2013, 13(3):149-151.
[18] 何逾祥, 罗素玲, 黄耀良, 等. 标准桃金娘油在儿童上气道咳嗽综合征治疗中的临床观察[J]. 中外医疗, 2013, 32(29):121-122.
[19] 马迪将, 诸琦, 杨金维, 等. 鼻喷激素联合鼻腔冲洗对儿童上气道咳嗽综合征的疗效观察[J]. 中国全科医学, 2014, 17(2):217-219. MA Dijiang, ZHU Qi, YANG Jinwei, et al. Effect of nasal spray hormone combined with nasal douche on upper airway cough syndrome in children[J]. Chin Gen Pract, 2014, 17(2):217-219.
[20] 王丽华, 曲大军. 高渗盐水鼻腔冲洗治疗小儿上气道咳嗽综合征的疗效观察[J].中国医药指南, 2012, 10(23):445-446. WANG Lihua, QU Dajun. The curative effect observation of child upper airway cough syndrome nasal douched by hypertonic saline solution[J]. Guide Chin Med, 2012, 10(23):445-446.
[21] 吴慧, 陈小红, 周胜, 等. 经鼻雾化吸入普米克令舒治疗上气道综合征临床研究[J]. 健康研究, 2014, 21(1):67-68.
[22] 王德辉, 孙琼, 王锋, 等. 高渗盐水对慢性鼻窦炎患者鼻腔黏膜纤毛清除功能的影响[J].山东大学耳鼻喉眼学报, 2007, 21(2):111-112. WANG Dehui, SUN Qiong, WANG Feng, et al. Effect of hypertonic saline on mucociliary clearance in patients with chronic rhinosinusitis[J]. J Otolaryngol Ophthalmol Shandong Univ, 2007, 21(2):111-112.
[23] Parsons DS. Chronic sinusitis: a medical or surgical disease? [J]. Otolaryngol Clin North Am, 1996, 29(1):1-9.
[24] 靳小雨. 中医辨证治疗上气道咳嗽综合征83例[J].中医研究, 2010, 23(7):55-57
[25] 方芳. 鼻后滴漏方配合穴位敷贴治疗小儿上气道咳嗽综合征疗效观察[J]. 中医儿科杂志, 2012, 8(4):41-42. FANG Fang. Effect observation of PNDS Decoction combined with application in the treatment of pediatric upper respiratory duct cough syndrome[J]. J Ped Trad Chin Med, 2012, 8(4):41-42.
[26] 郑贵亮, 宇雅萍, 朱玉华, 等. 影响儿童慢性鼻窦炎非手术疗效的多因素分析[J].山东大学耳鼻喉眼学报, 2006, 20(4):325-326. ZHENG Guiliang, YU Yaping, ZHU Yuhua, et al. Therapeutic efficacy of non-operation for chronic sinusitis in children: a multi-factor analysis[J]. J Otolaryngol Ophthalmol Shandong Univ, 2006, 20(4):325-326.
[27] 马亚琳, 任平治, 柴茂文, 等. 青少年鼻后滴漏综合征与腺样体肥大67例[J].中国眼耳鼻喉科杂志, 2009, 9(3):163-164. MA Yalin, REN Pingzhi, CHAI Maowen, et al. Correlation of postnasal drip syndrome with adenoid hypertrophy in adolescents[J]. Chin J Ophthalmol Otorhinolaryngol, 2009, 9(3):163-164.
[28] 冯勇刚, 俞海安, 朱鹃芬. 腺样体切除治疗儿童上呼吸道咳嗽综合征33例[J]. 中国眼耳鼻喉科杂志, 2009, 9(4):234-235. FENG Yonggang, YU Haian, ZHU Juanfen. Treatment of child upper airway cough syndrome with adenoidectomy in 33 cases[J]. Chin J Ophthalmol Otorhinolaryngol, 2009, 9(4):234-235.
[29] 敬尚林, 林楠,唐向荣. 儿童副鼻窦支气管炎疗效观察及分析[J]. 临床儿科杂志, 2013, 31(8):730-732. JING Shanglin, LIN Nan, TANG Xiangrong. Clinical observation and analysis of paranasal sinus bronchitis in children[J]. J Clin Ped, 2013, 31(8):730-732.
[30] 董晓艳,陆权,吴蓓蓉,等.中国儿童慢性咳嗽的治疗现状[J]. 中华儿科杂志, 2014, 52(3):163-171. DONG Xiaoyan, LU Quan, WU Beirong, et al. Current status of chronic cough treatment in Chinese children[J]. Chin J Ped, 2014, 52(3):163-171.
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