山东大学耳鼻喉眼学报 ›› 2019, Vol. 33 ›› Issue (4): 18-24.doi: 10.6040/j.issn.1673-3770.1.2019.039

• 研究进展 • 上一篇    下一篇

循环肿瘤细胞在头颈部鳞癌中的富集及检测

刘坤,张欣欣*()   

  1. 中国人民解放军总医院耳鼻咽喉头颈外科，北京 100853
  • 收稿日期:2019-06-10 出版日期:2019-07-16 发布日期:2019-07-22
  • 通讯作者: 张欣欣 E-mail:xinxinzhang66@hotmail.com
  • 作者简介:张欣欣，女，中国人民解放军总医院耳鼻咽喉头颈外科主任医师/教授，研究生导师。主要学术任职：中国医药教育协会头颈肿瘤专业委员会副主任委员，中国中西医结合学会耳鼻咽喉科分会头颈肿瘤专业委员会副主任委员，中国抗癌协会头颈肿瘤专业委员会委员，中国健康促进基金会靶向药物临床研究专项基金专家委员会委员，中华医学会耳鼻咽喉头颈外科学分会成员，CSCO头颈肿瘤专家委员会委员，《中华耳鼻咽喉头颈外科杂志》《中华耳科杂志》编委。主要研究方向为头颈部恶性肿瘤的发病机制、多分子靶向药物的研究及头颈部器官(包括喉、眼、舌及耳等)功能保护及鼻咽癌的综合治疗。以课题第一负责人获得美国NIH博士后培训基金及国家自然科学基金等9项基金。在国内外医学核心期刊上发表科研论著50余篇，其中SCI收录18篇，Medline收录19篇

Progress in clinical research on circulating tumor cells in squamous cell carcinoma of the head and neck

Kun LIU,Xinxin ZHANG*()   

  1. Department of Otorhinolaryngology Head and Neck Surgery, Chinese PLA General Hospital, Beijing 100853, China
  • Received:2019-06-10 Online:2019-07-16 Published:2019-07-22
  • Contact: Xinxin ZHANG E-mail:xinxinzhang66@hotmail.com

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摘要：

循环肿瘤细胞(CTCs)作为“液体活检”的方法之一，在头颈部鳞癌的早期诊断、判断预后及疗效、监测肿瘤复发与转移方面有重要的指导作用。就近年来循环肿瘤细胞的检测技术及其在头颈部鳞癌临床应用的研究进展进行综述。

关键词: 循环肿瘤细胞, 头颈部肿瘤, 肿瘤，鳞状细胞, 临床实验室技术

Abstract:

Circulating tumor cells (CTCs), as one of the materials of "liquid biopsy, " have important guiding roles in the early diagnosis of head and neck squamous cell carcinoma, judgment of prognosis and therapeutic response, and monitoring of tumor recurrence and metastasis. In this paper, the progress in research on CTCs in recent years and their clinical application in head and neck squamous cell carcinoma are reviewed

Key words: Circulating tumor cells, Head and neck neoplasms, Neoplasms, squamous cell, Clinical laboratory techniques

中图分类号: 

  • R739.6
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