脑干听觉诱发电位对脑外伤后持续植物状态评价的意义

山东大学耳鼻喉眼学报

脑干听觉诱发电位对脑外伤后持续植物状态评价的意义

程友, 王秋萍,钱宇虹,郭梦和,王天友,李泽卿

1．南京军区南京总医院耳鼻咽喉-头颈外科，江苏南京 210002；2．南方医科大学珠江医院耳鼻咽喉科，广东广州 510282

收稿日期:2006-07-02 修回日期:1900-01-01 出版日期:2006-08-24 发布日期:2006-08-24
通讯作者: 李泽卿

Evaluation of brainstem auditory evoked potential for patients with severe traumatic brain injury in persistent vegetative state

CHENG You,WANG Qiu-ping,QIAN Yu-hong,GUO Meng-he,WANG Tian-you,LI Ze-qing

1.Department of Otolaryngology & Head and Neck Surgery, Nanjing General Hospital of Nanjing Military Command, Nanjing 210002, Jiangsu, China; 2. Department of Otolaryngology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282,

Received:2006-07-02 Revised:1900-01-01 Online:2006-08-24 Published:2006-08-24
Contact: LI Ze-qing

摘要/Abstract

摘要： 目的：通过脑干听觉诱发电位（brainstem auditory evoked potential, BAEP）评估颅脑外伤后持续植物状态（persistent vegetative state, PVS）患者的脑干功能。方法：对25例（50耳）PVS患者行BAEP检测，并与对照组行单因素方差分析。结果：PVS患者的BAEP异常率为80%。其改变复杂多样，主要表现为ⅠV各波的异常或分化不良，甚至波形缺如；Ⅰ、Ⅲ、Ⅴ波潜伏期（peak latency, PL）延长，IV波间潜伏期（Interpeak latency, IPL）延长，双侧V波潜伏期的耳间差（interaural latency difference, ILD）增大；ⅢV与ⅠⅢ波IPL之比大于1。结论：PVS患者的BAEP结果呈多样性改变，反映了患者植物状态下存在不同程度的脑干损害，为其诊疗及预后判断提供了可靠的依据。

关键词: 脑干听觉诱发电位, 颅脑损伤, 持续植物状态

Abstract: To study the value of brainstem auditory evoked potential (BAEP) in evaluating the function of brainstem in patients with severe traumatic brain injury in persistent vegetative state(PVS). Methods: Twentyfive patients with severe traumatic brain injury in PVS were examined by BAEP and the data were compared with normal. Results: The abnormal rate of BAEP was 80%(20/25). The alterations included delay of peak latency of I, Ⅲ, and V waves, prolongation of interpeak latency between wave I and V， increase of interaural latency difference of wave V and greater interpeak latency between ⅢV and IⅢ. Conclusion: BAEP can be used to evaluate the function of brainstem in patients with severe traumatic brain injury in PVS and provide evidences for prognosis.

Key words: Traumatic brain injury, Brainstem auditory evoked potential, Persistent vegetative state

程友,王秋萍,钱宇虹,郭梦和,王天友,李泽卿 . 脑干听觉诱发电位对脑外伤后持续植物状态评价的意义[J]. 山东大学耳鼻喉眼学报, 2006, 20(4): 345-348 .

CHENG You,WANG Qiu-ping,QIAN Yu-hong,GUO Meng-he,WANG Tian-you,LI Ze-qing . Evaluation of brainstem auditory evoked potential for patients with severe traumatic brain injury in persistent vegetative state[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2006, 20(4): 345-348 .

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