低温等离子射频消融术治疗药物性鼻炎27例

doi:10.6040/j.issn.1673-3770.0.2021.395

摘要/Abstract

摘要： 目的探讨低温等离子射频消融术(LPRFA)治疗药物性鼻炎的疗效。方法对27例药物性鼻炎患者实施双侧下鼻甲LPRFA,统计并分析患者术前、术后3个月、术后6个月视觉模拟评分(VAS)和Lund-Kennedy鼻内镜评分及鼻阻力测量值。结果 VAS鼻内镜评分术前评分为(7.82±0.92)、术后3个月评分为(2.15±0.99),术后6个月评分为(2.26±1.06);Lund-Kennedy鼻内镜评分:术前评分为(3.22±0.58)、术后3个月评分为(1.15±0.86),术后6个月评分为(0.63±0.56);与术前相比,进行了LPRFA的患者术后3个月、6个月的VAS和Lund-Kennedy鼻内镜评分明显降低,差异有统计学意义(P<0.05);鼻窦CT和鼻内镜检查示鼻黏膜恢复良好,总鼻道较术前通畅,患者自述鼻塞症状明显改善,术前吸气总鼻阻力值为(0.97±0.50)kPa/L·s,呼气总鼻阻力值为(0.35±0.23)kPa/L·s,术后3个月的吸气总鼻阻力值为(1.01±0.84)kPa/L·s,呼气总鼻阻力值为(0.35±0.19)kPa/L·s,术后3个月患者吸气和呼气总鼻阻力值明显降低,差异有统计学意义(P<0.05)。结论采用LPRFA治疗药物性鼻炎后,患者鼻塞等鼻部症状明显缓解,生活质量得到提高,并在随访期(6个月)中,患者疗效稳定,LPRFA治疗药物性鼻炎值得临床推广应用。

关键词: 低温等离子射频消融术, 药物性鼻炎, 鼻阻力, 视觉模拟评分, Lund-Kennedy鼻内镜评分

Abstract: Objective To analyze the therapeutic effect of low-temperature plasma radiofrequency ablation(LPRFA)on rhinitis medicamentosa. Methods Twenty-six patients with rhinitis medicamentosa were treated using LPRFA in the bilateral inferior turbinates. The visual analog scale(VAS)score, Lund-Kennedy endoscopic nasal score, and nasal resistance measurements were collected and analyzed statistically at 3 months after surgery. Results The preoperative, 3-month postoperative, and 6-month postoperative VAS endoscopic scores were 7.82±0.92, 2.15±0.99, and 2.26±1.06, respectively. The preoperative, 3-month postoperative, and 6-month postoperative Lund-Kennedy nasal endoscopic scores were 3.22±0.58, 1.15±0.86, and 0.63±0.56, respectively. Patients who underwent LPRFA had significantly lower VAS and Lund-Kennedy endoscopic scores at 3 and 6 months postoperatively than the preoperative scores(P<0.05). Sinus CT and nasal endoscopy showed that the nasal mucosa had recovered well. The total nasal tract was unobstructed postoperatively compared with that before surgery. Furthermore, the patient-reported symptoms of nasal obstruction were significantly improved. The preoperative total nasal inspiratory resistance value was 0.97±0.50 kPa/L·s. The total nasal expiratory resistance value was 0.35±0.23 kPa/L·s. The total nasal inspiratory resistance value 3 months postoperatively was 1.01±0.84 kPa/L·s. The total expiratory nasal resistance was 0.35±0.19 kPa/L·s. The total inspiratory and expiratory nasal resistance significantly decreased at 3 months after surgery(P<0.05). Conclusion After treating rhinitis medicamentosa using LPRFA, the nasal symptoms such as nasal congestion were relieved, and the patient's quality of life improved. During the follow-up period(6 months), nasal obstruction and other nasal symptoms were gradually relieved. Hence, LPRFA should be recommended for the clinical treatment of rhinitis medicamentosa.

Key words: Low-temperature plasma radiofrequency ablation, Rhinitis medicamentosa, Nasal resistance, Visual analog scale, Lund-Kennedy nasal endoscopic score

中图分类号:

R765

李定波,唐志元,邓智毅,曾宪海,张秋航,王再兴. 低温等离子射频消融术治疗药物性鼻炎27例[J]. 山东大学耳鼻喉眼学报, 2022, 36(5): 11-17.

LI Dingbo, TANG Zhiyuan, DENG Zhiyi, ZENG Xianhai, ZHANG Qiuhang, WANG Zaixing. Curative effect analysis of low-temperature plasma radiofrequency ablation in 27 cases of drug-related rhinitis[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(5): 11-17.

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