咽喉反流性疾病的内镜下治疗

doi:10.6040/j.issn.1673-3770.0.2024.260

摘要/Abstract

摘要： 咽喉反流性疾病(laryngopharyngeal reflux disease, LPRD)是指胃十二指肠内容物反流至食管上括约肌以上的上呼吸消化道,包括鼻咽、口咽、咽喉和喉等部位,可引起上呼吸消化道的形态学改变及一系列症状和体征的总称,治疗一直以来以质子泵抑制剂为主导,部分药物治疗效果不佳或对药物治疗不耐受的患者,可考虑抗反流手术治疗。手术方式既往以腹腔镜胃底折叠术为主要方式,随着消化内镜技术的发展,逐步出现多种内镜下的抗反流新技术,它们具有住院天数短、症状评分下降明显、并发症少、经济等优势,如内镜下抗反流黏膜切除术、射频消融术、经口无切口胃底折叠术等,成为越来越多患者的选择,论文对内镜抗反流手术治疗LPRD进行综合叙述。

关键词: 咽喉反流性疾病, 内镜下经口无切口胃底折叠术, 抗反流黏膜切除术, 射频消融术, 内镜吻合器胃底折叠术

Abstract: Laryngopharyngeal reflux disease denotes the comprehensive manifestation of gastrointestinal contents refluxing to the region above the esophageal sphincter, eliciting a spectrum of symptoms and signs. Treatment has traditionally relied on proton pump inhibitors as the primary intervention, while laparoscopic fundoplication stands as the predominant surgical modality. With the continuous evolution of digestive endoscopy technology, a myriad of novel endoscopic techniques have emerged. These techniques confer advantages such as reduced hospitalization duration, marked alleviation in symptomatology, diminished incidence of complications, and favorable cost-effectiveness. Illustrative examples encompass endoscopic mucosal resection for anti-reflux, radiofrequency ablation, and transoral incisionless fundoplication. This manuscript offers a comprehensive exposition of such endoscopic modalities.

Key words: Laryngopharyngeal reflux disease, Transoral incisionless foundaplication, Anti-reflux mucosectomy, Radiofrequency Ablation, Medigus ultrasonic surgical endostapler

中图分类号:

R766.5

席晓宇,隋昕珂,陈升,李连勇,钟长青. 咽喉反流性疾病的内镜下治疗[J]. 山东大学耳鼻喉眼学报, 2024, 38(6): 61-65.

XI Xiaoyu, SUI Xinke, CHEN Sheng, LI Lianyong, ZHONG Changqing. Endoscopic treatment of laryngopharyngeal reflux disease[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(6): 61-65.

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