玻璃体腔内注射曲安奈德治疗严重糖尿病性黄斑水肿

山东大学耳鼻喉眼学报

玻璃体腔内注射曲安奈德治疗严重糖尿病性黄斑水肿

卢爱东¹，陈芳²，梁仲琪¹

1. 华北煤炭医学院附属开滦医院眼科，河北唐山 063000;2. 唐山市眼科医院眼科，河北唐山 063000

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2008-02-24 发布日期:2008-02-24
通讯作者: 卢爱东

Effects of triamcinolone acetonide treatment for diabetic macular edema

LU Ai-dong¹， CHEN Fang²， LIANG Zhong-qi ¹

1. Department of Ophthalmology， Kailuan Hospital, North China Coal Medical College,Tangshan 063000, Hebei, China;2. Department of Ophthalmology, Tangshan Ophthalmology Hospital, Tangshan 063000, Hebei, China

Received:1900-01-01 Revised:1900-01-01 Online:2008-02-24 Published:2008-02-24
Contact: LU Ai-dong

摘要/Abstract

摘要： 目的评价玻璃体腔内注射曲安奈德治疗糖尿病性黄斑水肿的疗效和安全性。方法对26 例严重糖尿病性黄斑水肿患者玻璃体腔内注射４mg曲安奈德治疗。结果随访观察6个月，最佳矫正视力均有不同程度改善，眼底荧光血管造影显示黄斑区荧光渗漏减少甚至部分患者无渗漏；光学相干断层扫描检查显示黄斑区视网膜厚度显著降低，黄斑水肿均减轻。治疗后第７d眼内压有不同程度升高，经局部滴降眼压药治疗１个月后眼压得到控制。术后发生假性眼内炎１例。结论曲安奈德治疗糖尿病性黄斑水肿安全有效。

关键词: 玻璃体腔内注射, 曲安奈德, 糖尿病性黄斑水肿

Abstract: To evaluate the therapeutic effects and security of intra-vitreous injection of triamcinolone acetonied (TA) for diabetic macular edema. Methods26 patients with diabetic macular edema were treated with intravitreous injection of 4mg TA. ResultsDuring 6 months follow-up， the visual acuity of all patients had improved in varying degrees. Fundus fluorescein angiography（FFA）showed a significant decrease in macular leakage， even no leakage in some patients. Optical coherence tomography（OCT）also showed a significant decrease in central macular thickness. Macular edema was improved in all patients, and the intraocular pressure increased after 7 days and was controlled in one month. Pseudoophthalmia was found in 1 patient. ConclusionTA is effective and safe for diabetic macular edema.

Key words: Triamcinolone acetonide, Diabetic macular edema , Intravitreous injection

中图分类号:

R774.5

卢爱东,陈芳,梁仲琪 . 玻璃体腔内注射曲安奈德治疗严重糖尿病性黄斑水肿[J]. 山东大学耳鼻喉眼学报, 2008, 22(1): 17-18 .

LU Ai-dong,CHEN Fang,LIANG Zhong-qi . Effects of triamcinolone acetonide treatment for diabetic macular edema[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(1): 17-18 .

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