异种脱细胞真皮基质在鼻中隔缺损修复中的应用

山东大学耳鼻喉眼学报 ›› 2009, Vol. 23 ›› Issue (5): 31-.

异种脱细胞真皮基质在鼻中隔缺损修复中的应用

赵利敏，张庆泉，孙岩，宋西城，张华，陈秀梅

青岛大学附属烟台毓璜顶医院耳鼻咽喉-头颈外科, 山东烟台 264000

收稿日期:2009-08-11 修回日期:2009-09-25 出版日期:2009-10-16 发布日期:2009-10-16
作者简介:赵利敏，女，主治医师，主要从事耳鼻咽喉疾病的临床研究。Email: zlmzmhh@yahoo.com.cn

Heterogeneous acellular dermal matrix in repairing mucosa defect of the nasal septum

ZHAO Li-min, ZHANG Qing-quan, SUN Yan, SONG Xi-cheng, ZHANG Hua, CHEN Xiu-mei

Department of Otorhinolaryngology & Head and Neck Surgery, Yantai Yuhuangding Hospital of Medical School of Qingdao University, Yantai 264000, Shandong, China

Received:2009-08-11 Revised:2009-09-25 Online:2009-10-16 Published:2009-10-16

摘要/Abstract

摘要：

目的探讨应用异种（牛）脱细胞真皮基质修复膜修复鼻中隔术后黏膜缺损的价值。方法对27例鼻中隔术后的黏膜缺损或穿孔应用异种（牛）脱细胞真皮基质修复膜行一期修复。结果随访4周～2年,24例鼻中隔偏曲矫正及肿瘤切除术后患者均无穿孔，3例鼻中隔穿孔患者一次性修复成功，外形满意。结论异种（牛）脱细胞真皮基质修复膜修复鼻中隔术后的黏膜缺损或穿孔手术操作简便，效果良好，有很好的临床应用价值。

关键词: 鼻中隔；修复外科手术；细胞外基质；生物敷料

Abstract:

Objective To study the clinical effect of the heterogeneity (cattle) acellular deunal matrix in repairing mucosa defect of the nasal septum. Methods Twenty-seven cases of mucosa defect or perforation of the nasal septum were treated with the heterogeneity acellular deunal matrix after surgery on the nasal septum. Results During a follow-up of 4 weeks to 2 years, twenty-four patients who had undergone nasal septal reconstruction or tumor resection had no perforation, and three patients with nasal septal perforation were successfully repaired. Conclusion The heterogeneity acellular deunal matrix can be easily obtained and it is a new method to repair mucosa defect of the nasal septum.

Key words: Nasal septum; Reconstructive surgical procedures; Extracellular matrix; Biological dressings

中图分类号:

R762

赵利敏，张庆泉，孙岩，宋西城，张华，陈秀梅. 异种脱细胞真皮基质在鼻中隔缺损修复中的应用[J]. 山东大学耳鼻喉眼学报, 2009, 23(5): 31-.

ZHAO Li-min, ZHANG Qing-quan, SUN Yan, SONG Xi-cheng, ZHANG Hua, CHEN Xiu-mei. Heterogeneous acellular dermal matrix in repairing mucosa defect of the nasal septum[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2009, 23(5): 31-.

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