JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2015, Vol. 29 ›› Issue (2): 9-11.doi: 10.6040/j.issn.1673-3770.0.2014.347

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Meta analysis of nasal corticosteroid treatment in the children with obstructive sleep apnea hypopnea syndrome

CHEN Xi, LI Jin-rang   

  1. Department of Otolaryngology & Head and Neck Surgery, Navy General Hospital, Beijing 100048, China
  • Received:2014-11-02 Online:2015-04-16 Published:2015-04-16

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Abstract: Objective To investigate the effectiveness of nasal corticosteroids to treat the children with obstructive sleep apnea hypopnea syndrome (OSAHS) using meta-analysis. Methods The published articles were searched from PubMed, Chinese Biomedical Literature CD-ROM databases, and China Academic Journals Full-text database bases on the inclusion and exclusion criteria. The results of the found studies were analyzed. Results 3 English articles and 88 cases were finally included. The results of Meta analysis showed that application of nasal corticosteroids significantly reduced the weighted mean AHI[weighted mean difference (WMD)=4.07, 95% CI(0.00, 8.14), P<0.000 01]. Conclusion Nasal corticosteroids may be helpful in ameliorating children with OSAHS.

Key words: Sleep apnea hypopnea syndrome, obstructive, Meta analysis, Nasal corticosteroids, Child

CLC Number: 

  • R766.7
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