JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2017, Vol. 31 ›› Issue (1): 50-54.doi: 10.6040/j.issn.1673-3770.0.2016.490

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Modified UPPP with low-temperature plasma tongue volume reduction and selective nasal cavity expansion for moderate to severe OSAHS: short-term efficacy and safety evaluation.

  

  1. 1. Department of Otorhinolaryngology, Huaian Second Peoples Hospital, Affiliated Huaian Hospital of Xuzhou Medical University, Huaian 223002, Jiangsu, China;2. Department of Otorhinolaryngology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu, China;3. Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu, China;4. Department of Anesthesiology, Huaian Second Peoples Hospital, Affiliated Huaian Hospital of Xuzhou Medical University, Huaian 223002, Jiangsu, China;5. Department of Radiology, Huaian Second Peoples Hospital, Affiliated Huaian Hospital of Xuzhou Medical University, Huaian 223002, Jiangsu, China;
  • Received:2016-11-21 Online:2017-02-16 Published:2017-02-16

Abstract: Objective To explore the clinical efficacy, safety and value of modified uvulopalatopharyngoplasty(UPPP)versus low-temperature plasma and selective nasal cavity vasodilatation with tongue volume reduction in the treatment of moderate and severe obstructive sleep apnea hypopnea syndrome(OSAHS). Methods The clinical data of 164 patients with moderate or serious OSAHS treated during Octorber, 2013 and May, 2016 were retrospective analyzed. According to the different surgical approaches, patients were divided into two groups: the observation group(n=82)and the control group(n=82). Patients in the observation group received modified UPPP versus low-temperature plasma and selective nasal cavity vasodilatation with tongue volume reduction, while patients in the control group underwent routine UPPP and nasal cavity vasodilatation. The clinic efficacy, operative complications, postoperative relapse and other indexes of the two groups were compared. Results Six months after surgery, the general effective rate of the observation group and control group was 81.7% and 62.2%, respectively, with statistically significant difference(P<0.05). One year after surgery, the general effective rate of the observation group and control group was 75.6% 山东大学耳鼻喉眼学报31卷1期 -怀德,等.低温等离子辅助改良腭咽成形联合舌减容和鼻腔扩容术对中重度OSAHS的近期疗效和安全性评价 \=-and 51.2%, respectively, with statistically significant difference(P<0.05). Fewer complications occurred in the observation group than in the control group. Conclusion The efficacy of modified UPPP plus low-temperature plasma and selective nasal cavity vasodilatation with tongue volume reduction can produce satisfactory clinical outcome for patients with moderate or severe OSAHS.

Key words: Sleep apnea, obstructive, Uvulopalatopharyngoplasty, Tongue volume reduction, Nasal cavity expansion, Low-temperature plasma

CLC Number: 

  • R766.7
[1] Hassid S, Afrapoli AH, Decaestecker C, et al. UPPP for snoring: long-term results and patient satisfaction[J]. Acta Otorhinolaryngol Belg, 2002, 56(2):157-162.
[2] Friedman M, Ibrahim H, Bass L. Clinical staging for sleep-disordered breathing[J]. Otolarynglology Head Neck Surg, 2002, 127(1):13-21.
[3] Friedman M, Ibrahim H, Joseph NJ. Staging of obstructive sleep apnea/hypopnea syndrome: a guide to appropriate treatment[J]. Laryngoscope, 2004, 114:454-459
[4] Delong Liu, Qingfeng Zhang. Anatomic characteristics of tongue coblation[J]. Otolarynglology-Head and Neck Surgery, 2008, 139(supplement, 2S1):199-200.
[5] 中华耳鼻咽喉头颈外科杂志编辑委员会, 中华医学会耳鼻咽喉头颈外科学分会咽喉学组. 阻塞性睡眠呼吸暂停低通气综合征诊断和外科治疗指南[J]. 中华耳鼻咽喉头颈外科杂志, 2009, 44(2):95-96.
[6] 张宝林, 郭睿, 龚维熙, 等. 软腭、舌根舌体低温等离子消融配合咽黏膜减张缝合治疗阻塞性睡眠呼吸暂停低通气综合征[J]. 山东大学耳鼻喉眼学报,2015,29(5):19-22. ZHANG Baolin, GUO Rui, GONG Weixi, et al. Reducing the volume of soft palate and tongue with low-temperature plasma combined with pharyngeal mucosal relaxation suture in patients with obstructive sleep apnea hypopnea syndrome[J]. J Otolaryngol Ophthalmol Shandong Univ, 2015, 29(5):19-22.
[7] 蒋新霞, 任秀敏, 王宝山. 低温等离子射频消融治疗阻塞性睡眠呼吸暂停低通气综合征32例[J]. 山东大学耳鼻喉眼学报,2006,20(2):184-185. JIANG Xinxia, REN Xiumin, WANG Baoshan. Low temperature plasma radiofrequency ablation in treatment of 32 patients with obstructive sleep apnea hypopnea syndrome[J]. J Otolaryngol Ophthalmol Shandong Univ, 2006, 20(2):184-185.
[8] 赵源庆, 袁勇, 公蕾, 等. 悬雍垂腭咽成形术中扩大咽峡和鼻咽峡的特点[J]. 中国组织工程研究与临床康复, 2007, 11(12):2393-2396. ZHAO Qingyuan, YUAN Yong, GONG Lei, et al. Dilatation of oropharyngeal and nasopharyngealisthmus in uvulopalatopharyngoplasty[J]. Chin J Tissue Eng Res, 2007, 11(12):2393-2396.
[9] 韩德民, 臧洪瑞. 鼻腔扩容技术[J]. 中国医学文摘(耳鼻咽喉科学), 2009, 24(4):197-199.
[10] Kanagalingam J, Rajeswaran R, Koteeha B. Long-term outcomes of laser-assisted uvulopalatoplaaty in 168 patients with snoring[J]. Laryngol Otol, 2006, 120:932-938.
[11] 赵晨, 李笑天, 刘亚奇, 等. 阻塞性睡眠呼吸暂停低通气综合征术后复发原因分析及再手术治疗研究[J]. 临床耳鼻咽喉头颈外科杂志,2013, 12:626-628. ZHAO Chen, LI Xiaotian, LIU Yaqi, et al. Research on failure reasons of surgical treatment of obstructive sleep apnea hypopnea syndrome and reoperation method[J]. Clin J Otorhinolarynol Head Neck Surg, 2013, 12:626-628.
[12] 洪燕丽, 李兆生, 沈伟林, 等. 改良悬雍垂腭咽成形术联合鼻部同期手术治疗重度阻塞性睡眠呼吸暂停低通气综合征分析[J]. 中国耳鼻咽喉头颈外科, 2013,20(7):370-372. HONG Yanli, LI Zhaosheng, SHEN Weilin, et al. Modified uvulopalatopharyngoplasty combined with one stage nasal surgery for patients with severe obstructive sleep apnea hypopnea syndrome[J]. Chin Otolaryngol Otolaryngol Head Neck Surg, 2013, 20(7):370-372.
[13] 张芳君, 邵军, 钱蔚颖, 等. 多平面手术联合治疗重度阻塞性睡眠呼吸暂停低通气综合征的临床观察[J]. 中国耳鼻咽喉颅底外科杂志,2013,19(1):19-23. ZHANG Fangjun, SHAO Jun, QIAN Weiying, et al. Evaluation of multi-level surgery for severe obstructive sleep apnea hypopnea syndrome[J]. Chin J Otorhinolaryngol Skull Base Surg, 2013, 19(1):19-23.
[14] 怀德, 王海旭, 曹影, 等. CO2激光辅助改良腭咽成形加选择性鼻腔扩容术治疗中重度阻塞性睡眠呼吸暂停低通气综合征[J]. 中华临床医师(电子版), 2016, 10(17):2543-2546. HUAI De, WANG Haixu, CAO Ying, et al. Improvement of CO2 laser assisted uvulopalatopharyngoplasty with selective expansion of the nasal cavity for the treatment of the moderate to severe obstructive sleep apnea hypopnea syndrome[J]. Chin J Clinicians(Electronic Ed), 2016, 10(17):2543-2546.
[15] 王海旭, 怀德, 曹影. 等. CO2激光辅助改良腭咽成形加选择性鼻腔扩容术治疗阻塞性睡眠呼吸暂停低通气综合征的疗效观察[J]. 中国中西医结合耳鼻咽喉科杂志, 2016, 24(4):272-275. WANG Haixu, HUAI De, CAO Ying, et al. Improvement of CO2 laser assisted uvulopalatopharyngoplasty with selective expansion of the nasal cavity for the treatment of the obstructive sleep apnea hypopnea syndrome[J]. Chin J Otorhinolaryngol Integ Med, 2016, 24(4):272-275.
[16] De Huai, Jun Dai, Min Xu, et al. Combination of CO2 laser-assisted uvulopalatopharyngoplasty and nasal cavity expansion enhances treatment of obstructive sleep apnea-hypopnea syndrome[J]. Int J Clin Exp Med, 2015, 8(10):19764-19774.
[17] 张庆丰. 耳鼻咽喉等离子手术学[M]. 北京: 人民卫生出版社, 2014:133-134.
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