JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2017, Vol. 31 ›› Issue (4): 51-53.doi: 10.6040/j.issn.1673-3770.0.2017.199

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Clinical analysis of 17 patients with primary non-Hodgkins lymphoma in the nose and the pharynx.

QIN He, HU Bin, YE Jingying   

  1. Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing 102218, China
  • Received:2017-05-10 Online:2017-08-16 Published:2017-08-16

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Abstract: Objective To analyze the clinical characteristics of primary non-Hodgkins lymphoma in the nose and pharynx. Methods The clinical data of 17 patients with pathologically confirmed non-Hodgkins lymphoma of the nose and pharynx were retrospectively reviewed. Results Six patients with non-Hodgkins lymphoma in the nasal cavity and paranasal sinuses showed nasal obstruction, nasal discharge, bloody rhinorrhea, malformation of the external nose, or hearing loss. Four patients with nasopharyngeal non-Hodgkins lymphoma presented with tinnitus and hearing loss. Seven patients with non-Hodgkins lymphoma in the oropharynx reported foreign body sensation in the throat, pharyngalgia, and dysphagia. The clinical manifestations of primary non-Hodgkins lymphoma in the nose and pharynx were non-specific. There was a large amount of necrotic tissue covering the surface of the neoplasm. In three patients, a biopsy was performed more than once before non-Hodgkins lymphoma was confirmed. Conclusion Diagnosis of primary non-Hodgkins lymphoma in the nose and pharynx is often missed. An accurate diagnosis is best achieved by pathological biopsy.

Key words: Nasal cavity, Nasopharynx, Oropharynx, Non-Hodgkins lymphoma

CLC Number: 

  • R739.6
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