Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2019, Vol. 33 ›› Issue (1): 128-130.doi: 10.6040/j.issn.1673-3770.0.2018.242

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Clinical effect of budesonide nasal irrigation shortly after functional endoscopic endonasal surgery of chronic sinusitis

ZHANG Wei1, LIU Yonggang2, JIANG Lingyan1   

  1. Ophthalmology Hospital of Chinese Academy of Chinese Medical Sciences, Beijing 100040, China
  • Online:2019-01-20 Published:2019-01-28

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Abstract: Objective To investigate the therapeutic effectiveness and feasibility of budesonide nasal irrigation shortly after Functional Endoscopic sinus surgery(FESS)of chronic sinusitis by observing the recovery of the nasal mucosa. Methods Fifty-five participants with chronic rhino-sinusitis were divided into treated(budesonide and saline irrigation)and control(saline irrigation)groups according to irrigation contents twice daily. VAS(nose obstruction, nasal discharge, smelling, and facial pain)and Kennedy scores were collected before FESS, while LKES and SNOT-22 scores were collected and compared before and after nasal irrigation. Results VAS scores were 17.80±3.22 in the treated group and 18.66±3.43 in the control group(P<0.05). Kennedy scores were 3.45±1.09 in the treated group and 3.37±1.05 in the control group(P<0.05). Scores of LKES and SNOT-22 were compared between the treated and control groups(P<0.05). There were no adverse events during treatment and irrigation. Conclusions Nasal symptoms shortly after FESS could be improved with budesonide irrigation, especially by reducing nasal mucositis after surgery and promoting nasal mucosa recovery.

Key words: Sinusitis, Budesonide, Nasal irrigation, Functional endoscopic surgery

CLC Number: 

  • R765.41
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