Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2019, Vol. 33 ›› Issue (6): 52-55.doi: 10.6040/j.issn.1673-3770.0.2019.256

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Correlation between the eosinophil count in the nasal secretions and pulmonary function in patients with allergic rhinitis

TIAN Qiushi, HU Wenting, PANG Mingjie   

  1. Department of Otolaryngology, Qingdao Municipal Hospital Affiliated to Qingdao University, Qingdao 266000, Shandong, China
  • Published:2019-12-23

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Abstract: Objective We aimed to study the correlation between the eosinophil(Eos)content in the nasal secretions and pulmonary function in patients with simple allergic rhinitis(AR)during the attack and stable period. Methods Overall, 102 adults with simple AR were included in the AR group, and 53 healthy individuals were included in the control group. We used pulmonary function tests to determine the pulmonary function indexes; nasal secretion smears were prepared, and the Eos count was determined during the attack and stable period. Result There were significant differences in the Eos count in the nasal secretions and peak expiratory flow(PEF), maximal expiratory flow at 75% of the forced vital capacity(MEF75), and forced expiratory volume in one second(FEV1)between the control group and AR group during the attack and stable period(P<0.001). The Eos count in the nasal secretions of the patients in the AR group during the attack and stable period was correlated with PEF, FEV1, and MEF75, and was significantly correlated with FEV1( r =-0.53, P<0.001). Conclusion We showed that the Eos count in the nasal secretions of patients with AR was closely related to pulmonary function. With the aggravation of airway allergy, pulmonary function decreased significantly.

Key words: Allergic rhinitis, Nasal secretion smear, Eosinophil, Pulmonary function.

CLC Number: 

  • R765.22
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