Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2021, Vol. 35 ›› Issue (1): 95-98.doi: 10.6040/j.issn.1673-3770.0.2020.227

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Endogenous endophthalmitis associated with Klebsiella pneumoniae pyogenic liver abscess: a report of 31 cases

PU Yadi1, LI Yuanbin2   

  1. 1. Medical College, Graduate School of Medicine, Qingdao University, Qingdao 266021, Shandong, China;
    2. Department of Ophthalmology, Yantai Yuhuangding Hospital, Qingdao University, Yantai 264000, Shandong, China
  • Published:2021-02-01

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Abstract: Objective To analyze the clinical characteristics of endogenous endophthalmitis(EE)associated with Klebsiella pneumoniae pyogenic liver abscess(KPPLA). Methods A retrospective analysis was performed, which included 31 patients(37 eyes)with EE associated with KPPLA admitted to the Yantai Yuhuangding Hospital affiliated to Qingdao University from 2013 to 2020. These patients were treated in the department of ophthalmology, hepatopancreatobiliary surgery, endocrinology, hematopathology, or respiratory medicine. General information, ophthalmologic findings, laboratory test results, etiology, imaging findings, treatment, and prognosis were analyzed. Results Most the 31 patients were middle-aged or elderly men, and most were diagosed with diabetic mellitus. Ten of the 37 eyes had no symptoms, which were diagnosed as EE during ocular examination. Twenty-two eyes were treated with an intravitreal injection, and 12 eyes were treated with vitrectomy. Ten eyes had improved visual acuity after treatment, while six eyes were enucleated. Conclusions Early symptoms of EE associated with KPPLA were atypical. Diabetes and severe systemic infection were the risk factors. Some patients had no ocular clinical manifestations in the early stage, and endophthalmitis was found in the ophthalmologic examination. Early ophthalmologic examination is important to detect asymptomatic EE. Timely and effective treatment can help preserve the patient's useful vision and improve the prognosis.

Key words: endogenous endophthalmitis, pyogenic liver abscess, Klebsiella pneumoniae, diabetic mellitus, asymptomatic, therapy

CLC Number: 

  • R771.2
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