ZI HaokunOverview,XIAO Xuping, LI Yunqiu
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|||LIU Bo, XIAO Xuping, LI Yunqiu, ZHOU En, GUO Renbin. Bilateral ossification of the auricular cartilage: a case report and literature review [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(4): 12-16.|
|||LI Dan, CHEN Tengyu, HUANG Yanfen, ZHOU Min, ZHOU Yixing, RUAN Yan, YAN Yajie. Research in the field of olfactory disorders in China—An analysis based on Citespace [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(4): 40-48.|
|||LU Xiaoyan, WEN Shuxin. Advances in the treatment of congenital choanal atresia [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(1): 138-142.|
|||YUAN Chenyang, LIU Yan, FANG Zhensheng. Advances on the effect of OSAHS on pulmonary function in children [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(1): 143-148.|
|||YANG Yanyan, YANG Yujuan, SONG Xicheng. Progress in aryl hydrocarbon receptor-induced inhibition of Th17 immune response in allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(1): 109-113.|
|||To explore the genesis, clinical diagnosis, treatment, and prevention mechanisms of the formation of stones within the nasal cavity and sinus as well as measures toreduce the rate of clinical misdiagnosis. MethodsA comprehensive analysis was conducted on six patients with nasal and sinus calculi who visited the hospital between April 2012 and November 2017. The etiology, pathology, clinical diagnosis, differential diagnosis, treatment, prevention, and complication management of the disease were summarized for each patient. ResultFive patients underwent surgery for the removal of stones from the nasal cavity and sinus under general anesthesia. Nasal endoscopy was also performed for the assessment of the related sinus passages. One patient recovered upon nasal irrigation and anti-inflammation treatment. All the patients were followed up for six months and the mucosal layer within the operation area that was epithelialized, recovered well. The symptoms disappeared without any additional complications. ConclusionNasal endoscopy in combination with the assessment of clinical manifestation and imaging are conducive to the diagnosis of the disease. Together, these could develop into an effective treatment regimen for nasal cavity and sinusoidal lithiasis.. Clinical experience in diagnosis and treatment of stone in nasal cavity and sinusZHAI Xingyou1, HOU Junsheng2, LI Xinjian1, WANG Xin1, XIE Yingli1, WANG Wenjia1 1. Department of Otorhinolaryngology Head and Neck Surgery, Hainan Hospital, General Hospital of PLA, Hainan Province Otorhinolaryngology Head and Neck Surgery Clinical Medical Research Center, Sanya 572013, Hainan, China; 2. Department of Otorhinolaryngology Head and Neck Surgery, the First Affiliated Hospital of Henan University, Kaifeng 475001, Henan, ChinaAbstract:Objective [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(4): 92-96.|
|||Central retinal artery occlusion(CRAO)is the most common cause of acute vision loss. Thrombolysis is a more radical treatment than conservative treatment, including arterial thrombolysis and intravenous thrombolysis, as well as the combination therapy of thrombolysis and other therapies. Thrombolysis treatment can improve the visual acuity of CRAO patients, but because of its lack of randomized controlled trials, further clinical studies are needed to determine their efficacy and safety. Our review summarized the application progress of thrombolysis in recent ten years, further evaluated its safety and effectiveness, and provided an evidence for clinical application.. Application progress of thrombolysis in retinal artery occlusionYANG Ming Overview WEI Wenbin Guidance Beijing Tongren Hospital, Capital Medical University / Beijing Tongren Eye Center / Beijing key Laboratory of Intraocular Tumor Diagnosis and Treatment / Beijing Ophthalmology&Visual Sciences Key Lab / Medical Artificial Intelligence Research and Verification Key Laboratory of the Ministry of Industry and Information Technology, Beijing 100730, ChinaAbstract: [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(4): 5-10.|
|||ObjectiveTo discuss the early diagnosis and multidisciplinary diagnosis and treatment of neovascular glaucoma in ocular ischemic syndrome. MethodsThe medical records of a 54-year-old male patient with cerebral infarction who presented with right-eye vision loss that had persisted for a week were reviewed. After slit-lamp examination and fluorescence angiography, he was diagnosed with ocular ischemic syndrome(OIS)complicated by neovascular glaucoma in the right eye and treated with intravitreal injection of anti-VEGF drugs and panretinal photocoagulation. ResultsAfter three months of treatment, the right-eye iris neovascularization subsided, and the intraocular pressure was controlled within normal limits. ConclusionOcular ischemia is often missed or misdiagnosed by ophthalmologists, neurologists, cardiologists, and vascular surgeons due to its insidious onset and complex clinical manifestations. Therefore, the establishment of multidisciplinary diagnosis and treatment can improve the prognosis of OIS patients.. Neovascular glaucoma in ocular ischemic syndrome: a case report and literature reviewQIN Shuqi1, WANG Luping1, JIANG Bin2, WANG Yanling1 1. Department of Ophthalmology, Beijing Friendship Hospital, Capital Medical University, Beijing 10050, China; 2. Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing 10050, ChinaAbstract: [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(4): 53-55.|
|||Nasal polyps(NP)are frequently divided into subtypes, including eosinophilic and neutrophilic, among others, according to their endotypes. However, the mechanisms of neutrophilic NP need to be further elucidated. This study explores the influence of 2-aminoethoxydiphenyl borate(2-APB)on inflammatory reactions of neutrophilic NP in vitro. MethodsWe used immunofluorescence and immunohistochemical staining to detect the infiltration of neutrophils(NEU)in normal nasal mucosa and NP tissues. These tissues were subsequently cultured in vitro using an organ culture technique, and concentrations of Orai1 and myeloperoxidase(MPO)were determined using enzyme-linked immunosorbent assay(ELISA). 2-APB was administered to both cultures, and the measurement of Orai1 and MPO concentrations using ELISA was repeated. ResultsAll samples were identified as neutrophilic NP. The number of NEU was higher in NP than in normal nasal mucosa. Concentrations of Orai1 and MPO were also higher in NP cultured in vitro than in normal tissue. After the administration of 2-APB, Orai1 protein and the mediator MPO were reduced significantly in the cultures. Conclusion2-APB may inhibit inflammatory reactions of neutrophilic NP in vitro.. 2- aminoethoxydiphenyl borate inhibits inflammatory reactions of neutrophilic nasal polyps in vitroDAI Fei, WEI Jinjin, TANG Xinyue, CHEN Zheng, LIN Lin Department of Otorhinolaryngology-Head and Neck Surgery, Huashan Hospital North of Fudan University, Shanghai 201907, ChinaAbstract:Objective〓 [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(4): 97-100.|
|||To investigate the relationship between nasal foreign bodies and allergic rhinitis in children. MethodsThis single-center study retrospectively evaluated the clinical data, treatment methods used, and complications reported for 161 pediatric patients with nasal foreign bodies who were treated between January 2017 and June 2018. ResultsA total of 161 patients were reviewed(91 boys and 70 girls). Among them, the age of high hair was 3-5 years old, and accounted for 81.4% of all the patients. Of these, 137(85.1%)children had nasal itching, rubbing nose, nose-picking, sneezing, epistaxis, nasal congestion, nasal hemorrhage, and other symptoms; 112 cases(69.6%)tested positive for sIgE(specific Immunoglobulin E)and were diagnosed with allergic rhinitis. The prevalence of allergic rhinitis in children with nasal foreign bodies was 69.6%, significantly higher than that reported for the general population(7.83%-20.42%; P<0.001). ConclusionIn children, nasal foreign bodies are closely associated with allergic rhinitis. Children with nasal foreign bodies should be particularly monitored for the development of allergic rhinitis. When allergic rhinitis is suspected, it should be promptly diagnosed and optimal treatment should be administered.. Relationship between nasal foreign body and allergic rhinitis in children: a preliminary studyLIN Xing, SHEN Ling, LIN Zongtong, YANG Zhongjie Department of Otorhinolaryngology, Fuzhou Children's Hospital of Fujian Province/Fuzhou Children's Hospital of Fujian Medical University, Fuzhou 350005, Fujian, ChinaAbstract: Objective〓 [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(4): 101-104.|
|||The occurrence and development of allergic rhinitis involves a variety of signal transduction pathways. Studying signal transduction pathways can promote the progress of pathogenesis research, suggesting that we can block the conduction of pathways in a pathway to achieve therapeutic effects. Open up new prospects for designing and developing more effective new drug treatments.The common signaling pathways in allergic rhinitis are reviewed in this article to provide a reference for the treatment of allergic rhinitis.. Advances in research on related signaling pathways in allergic rhinitisHUANG Jiali1 Review YANG Shurong2〓Guidance 1.Department of Clinical Medicine, Jiangxi University of Traditional Chinese Medicine,Nanchang 330000, Jiangxi, China 2.Department of Otolaryngology, Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang 330000, Jiangxi, ChinaAbstract: [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(4): 125-129.|
|||Rhinogenic headache is caused by rhinosinusitis or abnormal nasal anatomy. Currently, there are clear classifications and pain grading standards to diagnose the same. Further, its mechanism of action is now understood to involve trigeminal nerve stimulation and sensory neuropeptide substance P. Functional endoscopic surgery(FESS)is prioritized as a treatment modality. During surgery, it is imperative to restore the normal anatomy of the nasal cavity. Several clinical studies have reported that FESS was significantly effective in treating rhinogenic headache, with an overall effective rate of 90% and cure rate of 78%. Additionally, one report indicates that postoperative endoscopic examination and dressing change can effectively reduce the occurrence of complications and ensure safety of the treatment.. Dynamic analysis of rhinogenic headacheZHOU Fangming1, XIE Yan2, LIU Yang2 Overview JIANG Luyun2〓Guidance 1. Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan, China 2. Department of Otorhinolaryngology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan, ChinaAbstract: [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(4): 130-133.|
|||CHEN Kai, WANG Jun, TANG Yuedi. Nasal septum-nasal deformity surgery for correction of severe traumatic nasal deformity: a case report [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(1): 121-124.|
|||LI Yong. The difficulties, challenges, and strategy for diagnosing and treating pediatric sinusitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(6): 1-7.|
|||XU Geng. CT scans should not be routinely used for diagnosing chronic sinusitis in children [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(6): 8-9.|