ISSN 1673-3770 CN 37-1437/R
Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2020, Vol. 34 ›› Issue (4): 125-129.doi: 10.6040/j.issn.1673-3770.0.2019.355
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The occurrence and development of allergic rhinitis involves a variety of signal transduction pathways. Studying signal transduction pathways can promote the progress of pathogenesis research, suggesting that we can block the conduction of pathways in a pathway to achieve therapeutic effects. Open up new prospects for designing and developing more effective new drug treatments.The common signaling pathways in allergic rhinitis are reviewed in this article to provide a reference for the treatment of allergic rhinitis.
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| [1] | To investigate the relationship between nasal foreign bodies and allergic rhinitis in children. MethodsThis single-center study retrospectively evaluated the clinical data, treatment methods used, and complications reported for 161 pediatric patients with nasal foreign bodies who were treated between January 2017 and June 2018. ResultsA total of 161 patients were reviewed(91 boys and 70 girls). Among them, the age of high hair was 3-5 years old, and accounted for 81.4% of all the patients. Of these, 137(85.1%)children had nasal itching, rubbing nose, nose-picking, sneezing, epistaxis, nasal congestion, nasal hemorrhage, and other symptoms; 112 cases(69.6%)tested positive for sIgE(specific Immunoglobulin E)and were diagnosed with allergic rhinitis. The prevalence of allergic rhinitis in children with nasal foreign bodies was 69.6%, significantly higher than that reported for the general population(7.83%-20.42%; P<0.001). ConclusionIn children, nasal foreign bodies are closely associated with allergic rhinitis. Children with nasal foreign bodies should be particularly monitored for the development of allergic rhinitis. When allergic rhinitis is suspected, it should be promptly diagnosed and optimal treatment should be administered.. Relationship between nasal foreign body and allergic rhinitis in children: a preliminary studyLIN Xing, SHEN Ling, LIN Zongtong, YANG Zhongjie Department of Otorhinolaryngology, Fuzhou Children's Hospital of Fujian Province/Fuzhou Children's Hospital of Fujian Medical University, Fuzhou 350005, Fujian, ChinaAbstract: Objective〓 [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(4): 101-104. |
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| [4] | Xiaohan LIU,Xiaobing ZHANG. PU.1 transcription factor and helper Th9 cells with allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(5): 139-143. |
| [5] | ZHANG Guiyang, HUANG He, XIAN Zhi, ZHANG Hanwen, XIE Guicai. Evaluation of clinical effects of sublingual immunotherapy with Dermatophagoides farinae drops in patients of different age groups with allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(4): 60-65. |
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| [9] | Ruoxi CHEN,Qingzhao ZHANG,Meiping LU,Xinjie ZHU,Lei CHENG. Association of Toll-like receptor pathway gene polymorphisms with allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(3): 79-87. |
| [10] | Changyu QIU,Jun ZHOU,De′en ZHUANG,Qing YANG,Meiping LU,Lei CHENG. Artificial intelligence technology application in disclosing allergic rhinitis patients′ needs to otolaryngologists [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(3): 88-94. |
| [11] | Meiping LU,Lei CHENG. Current status of genetic research on allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(3): 36-41. |
| [12] | Yinshi GUO,Hui LU. Research progress of group Ⅱ innate lymphoid cells in the allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 9-12. |
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| [14] | QIN Ya′nan, WANG Lin, JIANG Yan, YAN Shu, CHEN Min, YU Longgang, LI Na. Characteristics of the distribution of inhaled allergens in patients with allergic rhinitis in Qingdao from 2008 to 2017 [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 67-72. |
| [15] | JIN Xing, HU Dayu, ZHU Li, DENG Furong, LIU Junxiu. Correlation between PM2.5 and upper airway resistance in patients with allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 77-80. |
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