Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2022, Vol. 36 ›› Issue (1): 131-137.doi: 10.6040/j.issn.1673-3770.0.2021.080

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Research progress on auditory risk factors and hearing screening methods among neonates

PAN Linlin, KONG Lingyi,ZHAI Feng, CHEN Jie   

  1. Department of Otolaryngology and Oral & Maxillofacial Surgery, Shanghai Children's Medical Center Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200127, China
  • Online:2022-01-10 Published:2022-02-22

Abstract: Newborn hearing loss results in not only delayed language and speech development but also poor social, recognitional, and educational performance. Several factors have an impact on neonatal hearing. However, the pathogenesis and characteristics of the factors vary based on the type of factor contributing to hearing impairment in neonates. Non-genetic factors mainly include preterm birth, low birth weight, neonatal hyperbilirubinemia, newborn hypoxia, infection, and ototoxic medication, whereas genetic factors mainly include GJB2, GJB3, SLC26A4, and mitochondrially encoded MT-RNR1 variation. Combined application of otoacoustic emission, automatic auditory brainstem response, and acoustic immittance test can effectively improve the accuracy of neonatal hearing impairment screening, which is helpful for early diagnosis and intervention.

Key words: Hearing loss, Neonates, Hearing screening, Otoacoustic emission, Automated auditory brainstem response, Acoustic immittance

CLC Number: 

  • R764.5
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