Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2024, Vol. 38 ›› Issue (2): 26-33.doi: 10.6040/j.issn.1673-3770.0.2023.085

• Original Article • Previous Articles     Next Articles

Epidemiological characteristics and prognostic factors associated with 4 526 cases of open globe injuries: a retrospective study

FU Qingyu, LIU Tiantian, WANG Pingping, LIU Longqian   

  1. Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China
  • Online:2024-03-20 Published:2024-03-29

Abstract: Objective To study the epidemiological features and prognostic factors of open globe injuries(OGI). Methods A retrospective study was conducted, focusing on OGI treated at West China Hospital, Sichuan University, between January 2009 and December 2020. Univariate analysis was used to determine the impact of various factors, including general patient information, causes of injury, complications, and the interval between injury and presentation to the hospital, on the visual outcomes at discharge. Factors that showed statistically significant differences were further analyzed using a multivariate binary Logistic regression model. Results Multivariate binary Logistic regression analysis revealed that, ethnic minorities, age groups of(45, 60)years, age groups of(60, 75)years, blunt object resulting in injury, falls resulting in injury, rehospitalization, prolonged hospital stay, complications included intraocular hemorrhage, dislocated lens, and orbital fractures are risk factors for discharge visual acuity <0.05(OR=1.355, 1.380, 2.387, 1.716, 1.601, 2.013, 1.889, 1.983, 1.857, 3.311; 95%CI=1.050-1.748, 1.140-1.670, 1.632-3.490, 1.290-2.282, 1.066-2.403, 1.668-2.429, 1.581-2.258, 1.627-2.417, 1.351-2.553, 2.109-5.198; all P<0.05). Conclusion OGI predominantly affect young and middle-aged males, with many injuries related to the workplace. Visual prognosis of OGI is generally poor, emphasizing the need for targeted preventive interventions.

Key words: Open globe injury, Ocular rupture injury, Mechanical eye injury, Intraocular hemorrhage, Dislocated lens, Orbital fractures

CLC Number: 

  • R779.1
[1] Iftikhar M, Latif A, Farid UZ, et al. Changes in the incidence of eye trauma hospitalizations in the United States from 2001 through 2014[J]. JAMA Ophthalmol, 2019, 137(1): 48-56. doi:10.1001/jamaophthalmol.2018.4685
[2] Mir TA, Canner JK, Zafar S, et al. Characteristics of open globe injuries in the United States from 2006 to 2014[J]. JAMA Ophthalmol, 2020, 138(3): 268-275. doi:10.1001/jamaophthalmol.2019.5823
[3] Heath Jeffery RC, Dobes J, Chen FK. Eye injuries: understanding ocular trauma[J]. Aust J Gen Pract, 2022, 51(7): 476-482. doi:10.31128/AJGP-03-21-5921
[4] 贺翔鸽. 机械性眼创伤的定义、分类和伤情判别[J]. 中华创伤杂志, 2001, 17(4): 251-252. doi: 10.3760/j: issn: 1001-8050.2001.04.026 HE Xiangge. Definition, classification and injury discrimination of mechanical eye trauma[J]. Chinese Journal of Traumatology, 2001, 17(4): 251-252. doi: 10.3760/j: issn: 1001-8050.2001.04.026
[5] 刘成刚, 陈丽鸿. 春节眼外伤临床特征和伤情预后分析[J]. 国际眼科杂志, 2018, 18(11): 2046-2050 LIU Chenggang, CHEN Lihong. Clinical features and prognosis of ocular injuries during Spring Festival[J]. International Eye Science, 2018, 18(11): 2046-2050
[6] 仝彤, 贺广秀, 李素华. 眼外伤患者创伤后应激障碍症状特征及社会心理因素[J]. 中国健康心理学杂志, 2021, 29(7): 996-1001. doi: 10.13342/j.cnki.cjhp.2021.07.009 TONG Tong, HE Guangxiu, LI Suhua. Symptom characteristics of post-traumatic stress disorder in patients with ocular trauma and analysis of social-psychosocial factors[J]. China Journal of Health Psychology, 2021, 29(7): 996-1001. doi: 10.13342/j.cnki.cjhp.2021.07.009
[7] Kyriakaki EDO, Detorakis ET, Bertsias AK, et al. Ocular trauma, visual acuity related to time of referral and psychosocial determinants, during COVID19 pandemic: a prospective study[J]. Exp Ther Med, 2023, 25(3): 130. doi:10.3892/etm.2023.11829
[8] Heindl LM, Trester M, Guo YW, et al. Anxiety and depression in patients wearing prosthetic eyes[J]. Graefes Arch Clin Exp Ophthalmol, 2021, 259(2): 495-503. doi:10.1007/s00417-020-04908-0
[9] Sahraravand A, Haavisto AK, Leivo T. Resource use and economic burden of eye injuries in Southern Finland[J]. Graefes Arch Clin Exp Ophthalmol, 2022, 260(2): 637-643. doi:10.1007/s00417-021-05399-3
[10] 邓美玉, 赵慧. 2011—2020年天津市眼科医院机械性开放性眼外伤调查研究[J]. 医学信息, 2022, 35(19): 118-120. doi: 10.3969/j.issn.1006-1959.2022.19.033 DENG Meiyu, ZHAO Hui. Investigation of mechanical open ocular trauma in Tianjin eye hospital from 2011 to 2020[J]. Medical Information, 2022, 35(19): 118-120. doi: 10.3969/j.issn.1006-1959.2022.19.033
[11] Peleja MB, da Cunha FBS, Peleja MB, et al. Epidemiology and prognosis factors in open globe injuries in the Federal District of Brazil[J]. BMC Ophthalmol, 2022, 22(1): 111. doi:10.1186/s12886-021-02183-z
[12] 邓瑾, 孙文涛, 宋虎平, 等. 机械性开放性眼外伤532例调查研究[J]. 陕西医学杂志, 2019, 48(5): 671-674. doi:10.3969/j.issn.1000-7377.2019.05.036 DENG Jin, SUN Wentao, SONG Huping, et al. The analysis of clinical characteristics of patients with open globe injury in one year[J]. Shaanxi Medical Journal, 2019, 48(5): 671-674. doi:10.3969/j.issn.1000-7377.2019.05.036
[13] Halawa O, Mitchell W, Zebardast N. Fall-related eye injury among older adults in the United States[J]. Am J Ophthalmol, 2021, 229: 82-89. doi:10.1016/j.ajo.2021.03.063
[14] Clynes MA, Harvey NC, Curtis EM, et al. The epidemiology of osteoporosis[J]. Br Med Bull, 2020, 133(1): 105-117. doi:10.1093/bmb/ldaa005
[15] Allen KD, Thoma LM, Golightly YM. Epidemiology of osteoarthritis[J]. Osteoarthr Cartil, 2022, 30(2): 184-195. doi:10.1016/j.joca.2021.04.020
[16] Clemson L, Stark S, Pighills AC, et al. Environmental interventions for preventing falls in older people living in the community[J]. Cochrane Database Syst Rev, 2023, 3(3): CD013258. doi:10.1002/14651858.CD013258.pub2
[17] Choovuthayakorn J, Chokesuwattanaskul S, Upaphong P, et al. Globe rupture: a single-center retrospective study of demographic patterns and outcomes[J]. Sci Rep, 2020, 10(1): 19139. doi:10.1038/s41598-020-76121-2
[18] Usmani B, Latif A, Iftikhar M, et al. Eye trauma in falls presenting to the emergency department from 2006 through 2015[J]. Br J Ophthalmol, 2021, 105(2): 198-204. doi:10.1136/bjophthalmol-2019-314669
[19] Chen A, Canner JK, Zafar S, et al. Characteristics of ophthalmic trauma in fall-related hospitalizations in the United States from 2000 to 2017[J]. Ophthalmic Epidemiol, 2022, 29(2): 206-215. doi:10.1080/09286586.2021.1914668
[20] 操文莉, 陈震, 邢怡桥. 1 587例机械性眼外伤流行病学特点及预后影响因素分析[J]. 实用预防医学, 2021, 28(10): 1201-1204. doi:10.3969/j.issn.1006-3110.2021.10.013 CAO Weili, CHEN Zhen, XING Yiqiao. Epidemiological characteristics and prognostic influencing factors of 1 587 cases of mechanical ocular trauma[J]. Practical Preventive Medicine, 2021, 28(10): 1201-1204. doi:10.3969/j.issn.1006-3110.2021.10.013
[21] 林树燕, 吴志群, 吴庆伟, 等. 195例眼外伤住院患者的受伤原因和临床分析[J]. 伤害医学(电子版), 2021, 10(3): 11-14. doi:10.3868/j.issn.2095-1566.2021.03.003 LIN Shuyan, WU Zhiqun, WU Qingwei, et al. Causes of injury and clinical analysis of 195 patients with ocular trauma[J]. Injury Medicine(Electronic Edition), 2021, 10(3): 11-14. doi:10.3868/j.issn.2095-1566.2021.03.003
[22] Chen HL, Han JJ, Zhang XL, et al. Clinical analysis of adult severe open-globe injuries in central China[J]. Front Med(Lausanne), 2021, 8: 755158. doi:10.3389/fmed.2021.755158
[23] 孙振蕊, 蒋晨, 丁琳. 新疆地区开放性眼外伤238例临床分析[J]. 中华眼外伤职业眼病杂志, 2018, 40(3): 191-194. doi:10.3760/cma.j.issn.2095-1477.2018.03.008
[24] 张芳,孟新丹,李军,等. 石河子地区儿童眼外伤的致伤原因和致盲因素分析 [J]. 国际眼科杂志, 2019, 19(4):636-640. doi:10.3980/j.issn.1672-5123.2019.4.24 ZHANG Fang, MENG Xindan, LI Jun, et al. A study on the causes of injury and blindness in children with ocular trauma in Shihezi Area[J]. International Eye Science, 2019, 19(4): 636-640. doi:10.3980/j.issn.1672-5123.2019.4.24
[25] 李冬嫦, 付婧, 王滔, 等. 儿童眼外伤2 298例的回顾性分析[J]. 国际眼科杂志, 2022, 22(3): 521-524. doi: 10.3980/j.issn.1672-5123.2022.3.36 LI Dongchang, FU Jing, WANG Tao, et al. Retrospective analysis of 2 298 children with ocular trauma[J]. International Eye Science, 2022, 22(3): 521-524. doi: 10.3980/j.issn.1672-5123.2022.3.36
[26] Hudson JL, Fan JC, Smiddy WE, et al. Acute- and delayed-onset endophthalmitis after open globe injuries: clinical features and visual acuity outcomes[J]. Retina, 2023, 43(4): 594-599. doi:10.1097/IAE.0000000000003707
[27] Blanch RJ, Bishop J, Javidi H, et al. Effect of time to primary repair on final visual outcome after open globe injury[J]. Br J Ophthalmol, 2019, 103(10): 1491-1494. doi:10.1136/bjophthalmol-2017-311559
[28] 胡宗莉, 蒋善明, 魏欣, 等. 急诊眼外伤致伤原因及致盲因素分析[J]. 眼科新进展, 2015, 35(2): 136-140. doi:10.13389/j.cnki.rao.2015.0036 HU Zongli, JIANG Shanming, WEI Xin, et al. Analysis of causes and blinding factors of emergency ocular trauma[J]. Recent Advances in Ophthalmology, 2015, 35(2): 136-140. doi:10.13389/j.cnki.rao.2015.0036
[29] Guven S, Durukan AH, Erdurman C, et al. Prognostic factors for open-globe injuries: variables for poor visual outcome[J]. Eye(Lond), 2019, 33(3): 392-397. doi:10.1038/s41433-018-0218-9
[30] 徐君,赵靖.日常生活实践与中华民族共同体意识形成路径——以藏族群众成都就医为例[J].中央民族大学学报(哲学社会科学版), 2022, 49(6): 14-24. doi:10.15970/j.cnki.1005-8575.2022.06.003
[31] Toiv A, Durrani AF, Zhou YS, et al. Risk factors for enucleation following open globe injury: a 17-year experience[J]. Clin Ophthalmol, 2022, 16: 3339-3350. doi:10.2147/OPTH.S377137
[32] Ojuok E, Uppuluri A, Langer PD, et al. Predictive factors of enucleation after open globe injuries[J]. Graefes Arch Clin Exp Ophthalmol, 2021, 259(1): 247-255. doi:10.1007/s00417-020-04794-6
[33] Gauthier AC, Oduyale OK, Fliotsos MJ, et al. Clinical characteristics and outcomes in patients undergoing primary or secondary enucleation or evisceration after ocular trauma[J]. Clin Ophthalmol, 2020, 14: 3499-3506. doi:10.2147/OPTH.S273760
[34] Zoega GM. Fire-works related eye injuries[J]. Laeknabladid, 2022, 108(12): 537. doi:10.17992/lbl.2022.12.718
[35] 刘红霞, 王少鹏, 路晖, 等. 外伤性眼球脱位于上颌窦一例报告[J]. 山东大学耳鼻喉眼学报, 2019, 33(2): 169-170. doi: 10.6040/j.issn.1673-3770.0.2017.475 LIU Hongxia, WANG Shaopeng, LU Hui, et al. A case of traumatic eyeball removal into the maxillary sinus[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(2): 169-170. doi: 10.6040/j.issn.1673-3770.0.2017.475
[36] 马宁, 陈敏, 刘薇, 等. 儿童颞骨骨折临床特点和治疗策略[J]. 山东大学耳鼻喉眼学报, 2022, 36(1): 13-19. doi: 10.6040/j.issn.1673-3770.0.2021.436 MA Ning, CHEN Min, LIU Wei, et al. Clinical characteristics and management of pediatric temporal bone fractures[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(1): 13-19. doi: 10.6040/j.issn.1673-3770.0.2021.436
[37] 吴双. 眼外伤手术围术期健康宣教和心理护理的效果观察[J]. 河南外科学杂志, 2020, 26(6): 188-190 WU Shuang. Observation on the effect of perioperative health education and psychological nursing in eye trauma surgery[J]. Henan Journal of Surgery, 2020, 26(6): 188-190
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