Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2024, Vol. 38 ›› Issue (6): 96-102.doi: 10.6040/j.issn.1673-3770.0.2024.046

• Clinical Research • Previous Articles    

Study of the laryngeal reflux symptom index and analysis of influencing factors in pregnant women

WEI Xin1, XING Dongsheng2,3, ZHAI Zhenwei1, YAN Aihui3, LIU Zhenyu2, CAO Hongwei3   

  1. 1. Department of Gynaecology and Obstetrics, Liaoyang Third People's Hospital, Liaoyang 111010, Liaoning, China2. Department of Otorhinolaryngology, Liaoyang Central Hospital, Liaoyang111010, Liaoning, China 3. Department of Otorhinolaryngology & Head and Neck Surgery, The First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning, China
  • Published:2024-12-13

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Abstract: Objective To explore the throat reflux in women in the course of pregnancy and analyze the influencing factors. Methods The medical records of pregnant women from January 2020 to October 2023 were prospectively collected, and the number of reflux symptoms, age, height, and corresponding gestational weight, body mass index, uterine length, and abdominal circumference were recorded for statistical analysis. Results This study included 150 valid respondents and 1350 valid questionnaires from 150 groups, including 381 questionnaires with RSI>13 points. From 22 to 46 years old, Mean(29.66±4.971)years; 153 to 175 cm, Mean(163.0±5.005)cm; Body mass of 43 to 86 kg when enrollment, Mean(58.83±8.924)kg, BMI(16.18-29.76), average(22.12±2.908), from(35+4)weeks to(41+6)weeks at delivery, Body mass 55 to 124 kg, mean(76.19±12.52)kg, BMI(20.70 to 42.41), Average(28.63±4.380). As the gestational age increases, Gradually increase increased body mass, BMI, RSI. RSI positive rate in early pregnancy was 19.33%, second trimester 33.33%, Late pregnancy trimester 66.67%, The difference was statistically significant(P<0.05). Univariate analysis of the influence of RSI, RSI, 13 by gestational age, age, height, BMI and abdominal circumference, where the gestational week comparison difference was statistically significant(P<0.05). The other factors were not significant(P>0.05). Univariate analysis of the effects of gestational age, age, height, BMI, uterine length, and abdominal circumference on RSI>13 in the middle and late trimester. Among them, gestational age, BMI, uterine length and abdominal circumference were significantly different(P<0.05), There was no significant difference between age and height(P>0.05).In multivariate Logistic regression analysis, four factors including gestational age, BMI, uterine length, and abdominal circumference showed that BMI and abdominal circumference on RSI>13(P<0.05), an independent risk factor for RSI>13, ROC for AUC=0.922, 27.265, ROC for abdominal circumference and RSI>13, AUC=0.896, 88.5, were statistically significant(P<0.001). Conclusion With the increase of BMI and abdominal circumference during pregnancy, the proportion of RSI>13 increased,BMI and abdominal circumference can be used as important indicators for obstetricians to assess whether pregnant women are at risk of LPRD.

Key words: Laryngopharyngeal reflux, Reflux symptom index, Pregnant women, Body mass index, Circumference of abdomen

CLC Number: 

  • R766.5
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