光学相干断层扫描血管成像在全身疾病中的临床应用研究进展

doi:10.6040/j.issn.1673-3770.0.2024.225

Abstract

Abstract: Systemic diseases refer to conditions that affect multiple organs throughout the body. Many systemic diseases have different degrees of damage to the eye. An in-depth study of the relationship between ophthalmology and systemic diseases can enhance the comprehensive diagnostic and therapeutic level in both fields. Optical coherence tomography angiography(OCTA)provides non-invasive, high-resolution three-dimensional images allowing for detailed observation of the conjunctival, iris, retinal, and choroidal blood vessels. OCTA has been widely used in ophthalmology, which is of great significance in the observation and follow-up of fundus diseases, such as macular edema, choroidal neovascularization, diabetic retinopathy, and retinal branch vein occlusion. Recent studies have shown that OCTA can not only be used for the early screening and diagnosis of neurodegenerative diseases, but also for assessing the severity of critical illnesses and carotid artery stenosis, as well as evaluating the effects of treatment. Furthermore, OCTA has been applied in assessing disease activity in systemic lupus erythematosus and has demonstrated significant value in constructing disease risk prediction models. In this article, we review the latest advances in the application of OCTA in various systemic diseases, discusses its potential clinical value, and provides insights for further application of OCTA in the field of systemic diseases.

Key words: Optical coherence tomography angiography(OCTA), Systemic diseases, Microvascular changes, Clinical application, Recent advances

CLC Number:

R771.3

LI Shiqiang, MA Yan, WANG Jiawei. Advances in clinical applications of optical coherence tomography angiography in systemic diseases[J].Journal of Otolaryngology and Ophthalmology of Shandong University, 2026, 40(1): 127-134.

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