Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2019, Vol. 33 ›› Issue (2): 12-16.doi: 10.6040/j.issn.1673-3771.1.2019.009

• Invited Review • Previous Articles     Next Articles

Status of surgical treatment for recurrent nasopharyngeal carcinoma

Dongping CHEN*(),Zhihuan YANG,Yan ZHANG,Nan FANG,Bin QI   

  1. Department of Radiotherapy, Cancer Center of Guangzhou Medical University, Guangzhou 510095, Guangdong, China
  • Received:2019-02-10 Online:2019-03-20 Published:2019-03-28
  • Contact: Dongping CHEN E-mail:chen_dpgz@163.com

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Abstract:

Among the modalities for managing recurrent nasopharyngeal carcinoma, surgical treatment has attracted increased attention. With the continuous improvement in surgical techniques, especially the development of endoscopic nasopharyngoscopy, the standard treatment for recurrent nasopharyngeal carcinoma has gradually changed from re-radiotherapy to surgery. This paper reviews the important literature published in recent years; introduces various surgical methods for recurrent nasopharyngeal carcinoma treatment; and analyzes the advantages, disadvantages, curative effects; and side effects of these surgical methods.

Key words: Nasopharyngeal neoplasms, Recurrence, Surgical procedures, operative

CLC Number: 

  • R739.6
1 Lai SZ , Li WF , Chen L , et al. How does intensity-modulated radiotherapy versus conventional two-dimensional radiotherapy influence the treatment results in nasopharyngeal carcinoma patients?[J]. Int J Radiat Oncol Biol Phys, 2011, 80 (3): 661- 668.
doi: 10.1016/j.ijrobp.2010.03.024
2 Ng WT , Lee MC , Chang AT , et al. The impact of dosimetric inadequacy on treatment outcome of nasopharyngeal carcinoma with IMRT[J]. Oral Oncol, 2014, 50 (5): 506- 512.
doi: 10.1016/j.oraloncology.2014.01.017
3 Stoker SD , van Diessen JN , de Boer JP , et al. Current treatment options for local residual nasopharyngeal carcinoma[J]. Curr Treat Options Oncol, 2013, 14 (4): 475- 491.
doi: 10.1007/s11864-013-0261-5
4 To EW , Teo PM , Ku PK , et al. Nasopharyngectomy for recurrent nasopharyngeal carcinoma: an innovative transnasal approach through a mid-face deglove incision with stereotactic navigation guidance[J]. Br J Oral Maxillofac Surg, 2001, 39 (1): 55- 62.
doi: 10.1054/bjom.2000.0479
5 Wei WI , Lam KH , Sham JS . New approach to the nasopharynx: the maxillary swing approach[J]. Head Neck, 1991, 13 (3): 200- 207.
doi: 10.1002/(ISSN)1097-0347
6 曾宗渊. 鼻咽癌手术治疗的地位与手术治疗方式[J]. 中华肿瘤防治杂志, 2006, 13 (6): 401- 402.
doi: 10.3969/j.issn.1673-5269.2006.06.001
ZENG Zongyuan . Current status of surgical trenment for nasopharyngeal cancer[J]. Chinese Journal of Cancer Prevention and Treatment, 2006, 13 (6): 401- 402.
doi: 10.3969/j.issn.1673-5269.2006.06.001
7 Yoshizaki T , Ito M , Murono S , et al. Current understanding and management of nasopharyngeal carcinoma[J]. Auris Nasus Larynx, 2012, 39 (2): 137- 144.
doi: 10.1016/j.anl.2011.02.012
8 韩非, 卢泰祥. 复发鼻咽癌的临床特点及挽救性治疗[J]. 中华耳鼻咽喉头颈外科杂志, 2012, 47 (3): 261- 264.
doi: 10.3760/cma.j.issn.1673-0860.2012.03.023
9 陈卓.鼻咽癌放疗后复发和广泛颅底骨坏死的内镜手术疗效观察[D].广州:南方医科大学, 2017.
10 Na ara S , Amit M , Billan S , et al. Outcome of Patients Undergoing Salvage Surgery for Recurrent Nasopharyngeal Carcinoma: a Meta-analysis[J]. Ann Surg Oncol, 2014, 21 (9): 3056- 3062.
doi: 10.1245/s10434-014-3683-9
11 Rui Y , Xiong Z , Yi-Jun H , et al. Salvage endoscopic nasopharyngectomy is superior to intensity-modulated radiation therapy for local recurrence of selected T1-T3 nasopharyngeal carcinoma-A case-matched comparison[J]. Radiother Oncol, 2015, 115 (3): 399- 406.
doi: 10.1016/j.radonc.2015.04.024
12 Bian X , Chen H , Liao LM . A retrospective study of salvage surgery for recurrent nasopharyngeal carcinoma[J]. Int J Clin Oncol, 2012, 17 (3): 212- 217.
doi: 10.1007/s10147-011-0276-5
13 Wei WI , Ho WK . Transoral robotic resection of recurrent nasopharyngeal carcinoma[J]. Laryngoscope, 2010, 120 (10): 2011- 2014.
doi: 10.1002/lary.21059
14 Yin Tsang RK , Ho WK , Wei WI . Combined transnasal endoscopic and transoral robotic resection of recurrent nasopharyngeal carcinoma[J]. Head Neck, 2012, 34 (8): 1190- 1193.
doi: 10.1002/hed.21731
15 Wei WI , Lam KH , Ho CM , et al. Efficacy of radical neck dissection for the control of cervical metastasis after radiotherapy for nasopharyngeal carcinoma[J]. Am J Surg, 1990, 160 (4): 439- 442.
doi: 10.1016/S0002-9610(05)80561-6
16 韩立涛, 渠宁, 史荣亮, 等. 鼻咽癌放化疗后颈部淋巴结残留及复发的外科治疗综述[J]. 中国癌症杂志, 2017, 27 (6): 505- 509.
doi: 10.19401/j.cnki.1007-3639.2017.06.018
HAN Litao , QU Ning , SHI Rongliang , et al. Review in the surgical management for residual and recurrent neck lymph node of nasopharyngeal carcinoma after radiotherapy and chemotherapy[J]. China Oncology, 2017, 27 (6): 505- 509.
doi: 10.19401/j.cnki.1007-3639.2017.06.018
17 夏良平, 曾宗渊, 陈直华, 等. 鼻咽癌放疗后颈淋巴结复发和残留的外科治疗[J]. 中华耳鼻咽喉头颈外科杂志, 2005, 40 (2): 95- 99.
doi: 10.3760/j.issn:1673-0860.2005.02.005
XIA Liangping , ZENG Zongyuan , CHEN Zhihua , et al. Surgery for the recurrent and persistent lymph node of nasopharyngeal carcinoma after radiotherapy[J]. Chinese JOurnal of Otorhinolaryngology Head and Neck Surgery, 2005, 40 (2): 95- 99.
doi: 10.3760/j.issn:1673-0860.2005.02.005
18 Chen H , Chen JH , Wang MX , et al. Retrospective study of selective neck dissection versus radical neck dissection as salvage therapy for patients with recurrent nasopharyngeal squamous cell carcinoma[J]. J Craniomaxillofac Surg, 2014, 42 (8): 1655- 1658.
doi: 10.1016/j.jcms.2014.05.008
19 Chen JY , Zhang L , Ji QH , et al. Selective neck dissection for neck residue of nasopharyngeal carcinoma: A prospective study[J]. J Craniomaxillofac Surg, 2015, 43 (8): 1571- 1576.
doi: 10.1016/j.jcms.2015.06.037
20 Lin CY , Tsai ST , Jin YT , et al. Outcome of surgical management of persistent or recurrent neck mass in patients with nasopharyngeal carcinoma after radiotherapy[J]. Eur Arch Otorhinolaryngol, 2008, 265 (S1): 69- 74.
doi: 10.1007/s00405-007-0552-1
21 王刘倩, 邓安春, 赵力, 等. 鼻咽癌放疗后的挽救性治疗研究进展[J]. 国际耳鼻咽喉头颈外科杂志, 2018, 42 (3): 154- 160.
doi: 10.3760/cma.j.issn.1673-4106.2018.03.007
WANG Liuqian , DENG Anchun , ZHAO Li , et al. Research progress of salvage therapy for nasopharyngeal carcinoma after radiotherapy[J]. International Journal of Dermatology and Venereology, 2018, 42 (3): 154- 160.
doi: 10.3760/cma.j.issn.1673-4106.2018.03.007
22 葛明华. 颈淋巴清扫术[M]. 北京: 军事医学科学出版社, 2009.
23 楼建林, 王升晔, 郭良, 等. 鼻咽癌放疗后颈部淋巴结复发或残留的手术治疗[J]. 中华耳鼻咽喉头颈外科杂志, 2014, 49 (4): 300- 304.
doi: 10.3760/cma.j.issn.1673-0860.2014.04.008
LOU Jianlin , WANG Shengye , GUO Liang , et al. Salvage surgery for neck recurrence or residue of nasopharyngeal carcinoma after primary radiotherapy[J]. Chinese Journal of Otorhinolaryngology Head and Neck Surgery, 2014, 49 (4): 300- 304.
doi: 10.3760/cma.j.issn.1673-0860.2014.04.008
24 傅敏仪, 叶飞, 陈国平, 等. 鼻咽癌放疗后颈部淋巴结残留和复发的分布及处理[J]. 现代肿瘤医学, 2014, 22 (12): 2824- 2826.
doi: 10.3969/j.issn.1672-4992.2014.12.16
FU Minyi , YE Fei , CHEN Guoping , et al. Distribution and management of recurrent and persistent lymph node of nasopharyngeal carcinoma after radiotherapy[J]. Journal of Modern Oncology, 2014, 22 (12): 2824- 2826.
doi: 10.3969/j.issn.1672-4992.2014.12.16
25 Li JC , Hu CS , Jiang GL , et al. Dose escalation of three-dimensional conformal radiotherapy for locally recurrent nasopharyngeal carcinoma: a prospective randomised study[J]. Clin Oncol (R Coll Radiol), 2006, 18 (4): 293- 299.
doi: 10.1016/j.clon.2006.02.003
26 Poon D , Yap SP , Wong ZW , et al. Concurrent chemoradiotherapy in locoregionally recurrent nasopharyngeal carcinoma[J]. Int J Radiat Oncol Biol Phys, 2004, 59 (5): 1312- 1318.
doi: 10.1016/j.ijrobp.2004.01.037
27 Wu SX , Chua DT , Deng ML , et al. Outcome of fractionated stereotactic radiotherapy for 90 patients with locally persistent and recurrent nasopharyngeal carcinoma[J]. Int J Radiat Oncol Biol Phys, 2007, 69 (3): 761- 769.
doi: 10.1016/j.ijrobp.2007.03.037
28 Yu KH , Leung SF , Tung SY , et al. Survival outcome of patients with nasopharyngeal carcinoma with first local failure: a study by the Hong Kong Nasopharyngeal Carcinoma Study Group[J]. Head Neck, 2005, 27 (5): 397- 405.
doi: 10.1002/hed.20161
29 边学, 徐震纲, 唐平章, 等. 鼻咽癌放射治疗失败后的挽救性手术[J]. 中华耳鼻咽喉头颈外科杂志, 2006, 41 (11): 871- 873.
doi: 10.3760/j.issn:1673-0860.2006.11.022
BIAN Xue , XU Zhengang , TANG Pingzhang , et al. Salvage surgery for nasopharyngeal carcinoma after failure of radiotherapy[J]. Chinese Journal of Otorhinolaryngology Head and Neck Surgery, 2006, 41 (11): 871- 873.
doi: 10.3760/j.issn:1673-0860.2006.11.022
30 文卫平, 陈明远. 经鼻内镜手术切除局部复发性鼻咽癌[J]. 中国医学文摘-耳鼻咽喉科学分册, 2007, 22 (4): 190- 192.
doi: 10.19617/j.issn1001-1307.2007.04.002
31 屠规益. 以手术为主治疗鼻咽癌背离循证医学原则[J]. 循证医学, 2002, 2 (4): 196- 198.
doi: 10.3969/j.issn.1671-5144.2002.04.002
TU Guiyi . Therapy for the nasopharyngeal neoplasms by surgery departs from the principle of evidence-based medicine[J]. The Journal of Evidence-Based Medicine, 2002, 2 (4): 196- 198.
doi: 10.3969/j.issn.1671-5144.2002.04.002
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