Abstract: Objective To investigate the safety, efficacy and characteristics of rigid gas permeable contact lens (RGPCL) for correction of ammetropia after penetrating keratoplasty. Methods 23 eyes of 19 patients after penetrating keratoplasties were fitted with RGPCL. Among them, 2 had spherical posterior surface designs, 17 had aspherical designs and 4 had special keratoconus designs. The status was in a flat and three points fitting. All were followed up for six to thirtyseven months. Results All patients achieved visual acuity over 0.5 and 14 even equal or over 0.8, which was significantly different from the best corrected visual acuity with glasses. After wearing RGP, the K value decreased from 47.18±4.92D to 45.69±3.04D and corneal astigmatism from 6.53±2.26D to 3.95±1.87D（P＜0.05）. There were no significant changes in corneal endotheliu. No significant epithelial or corneal complications were observed during the follow up period. Conclusions RGPCL is ideal for refraction reconstruction of ammetropia after penetrating keratoplasty. Both flexible and continuous wearing are safe. It is easier to achieve an ideal fitting state with the aspherical design and special posterior surface design.

Key words: Keratoplasty, Rigid gas permeable contact lens, Refraction, Reconstruction