Abstract: Objective To evaluate the effects of subtotal-patathyroidectomy and total-parathyroidectomy with parathyroid tissue transplantation in the forearm in treatment of severe secondary hyperpathyroidism. Methods The clinical data of 11 patients subjected to subtotal-patathyroidectomy (group Ⅰ) and 4 patients subjected to total-parathyroidectomy with parathyroid tissue transplantation in the forearm (group Ⅱ) were retrospectively analyzed. The PTH and Ca levels before the operations, and 1 day and 6 months after the operations were determined. Results The PTH level was remarkably decreased after operations but there was no significant difference between the post-operative 1 day and the post-operative 6 month groups. The Ca level was also significantly decreased after the operations but it only had statistic significances in group Ⅰ. Conclusion Both subtotal parathyroidectomy and total parathyroidectomy with parathyroid tissue transplantation in the forearm have therapeutic effects for renal secondary hyperparathyroidism and the effects had no significant differences in the short term.

Key words: Hyperparathyroidism, secondary, Autotransplantation, Subtotal parathyroidectomy, Total parathyroidectomy