JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2018, Vol. 32 ›› Issue (2): 14-18.doi: 10.6040/j.issn.1673-3770.1.2018.002

Previous Articles     Next Articles

The relationship between allergic reaction and children obstructive sleep apnea hypopnea syndrome

WANG Yan, SHI Xiaoli   

  1. Department of Otolaryngology, QiLu Hospital of Shandong University;Key Laboratory of Otolaryngology, NHFPC(Shandong University), Jinan 250012, Shandong, China
  • Received:2018-01-15 Online:2018-03-20 Published:2018-03-20

Abstract: Children obstructive sleep apnea hypopnea syndrome, which have the high incidence, endangering children growth seriously, is a kind of ENT common diseases. The high incidence of OSAHS in children is related to many factors, the most common of that is tonsil hypertrophy and adenoid hypertrophy. Tonsils and adenoids are lymphatic tissues, locating at the entrance to the digestive tract and respiratory tract, and exposing to various ingestion and allergens for a long time. More and more studies have shown that allergic reactions play an important role in the pathogenesis of OSAHS in children, however, different opinions have also been put forward. This article summarizes the latest research results, and the relationship between allergic reactions and OSAHS in children, and then provides the basis for the medical treatment of children OSAHS.

Key words: Children, Allergy, adenotonsillar hypertrophy, Sleep apnea, obstructive

CLC Number: 

  • R766.7
[1] 中华耳鼻咽喉头颈外科杂志编委会, 中华医学会耳鼻咽喉科学分会. 儿童阻塞性睡眠呼吸暂停低通气综合征诊疗指南草案(乌鲁木齐)[J]. 中华耳鼻咽喉头颈外科杂志, 2007, 42(2): 83-84. Editorial Board of Chinese Journal of Otorhinolary. Chinese Otorhinolaryngology of Chinese Medical Ass. Draft of guidelines for the diagnosis and treatment of pediatric sleep apnea hypopnea syndrome(Urumqi)[J].Chin J Otorhinolaryngol Head Neck Surg, 2007, 42(2):83-84.
[2] Sadeghi-Shabestari M, Jabbari Moghaddam Y, Ghaharri H. Is there any correlation between allergy and adenotonsillar tissue hypertrophy? [J]. Int J Pediatr Otorhinolaryngol, 2011, 75(4): 589-591.
[3] 杨素娜, 窦训武. 100例腺样体肥大儿童的血清过敏原检测分析 [J]. 中外医学研究, 2016, 14(11): 42-43. YANG Suna,DOU Xunwu. Serum allergen detection and analysis for 100 cases of adenoid hypertrophy[J]. Chin Foreign Med Res, 2016, 14(11): 42-43.
[4] Olusesi AD, Undie NB, Amodu JE. Allergy history as a predictor of early onset adenoids/adenotonsillar hypertrophy among Nigerian children [J]. Int J Pediatr Otorhinolaryngol, 2013, 77(6): 1032-1035.
[5] Ameli F, Brocchetti F, Tosca MA, et al. Adenoidal hypertrophy and allergic rhinitis: is there an inverse relationship? [J]. Am J Rhinol Allergy,2013, 27(1): 5-10.
[6] Nuhoglu C, Nuhoglu Y, Bankaoglu M, et al. A retrospective analysis of adenoidal size in children with allergic rhinitis and nonallergic idiopathic rhinitis [J]. Asian Pac J Allergy Immunol, 2010, 28(2-3): 136-140.
[7] Karaca CT, Toros SZ, Noseri H, et al. Role of allergy in children with adenotonsillar hypertrophy [J]. J Craniofac Surg, 2012, 23(6): 611-613.
[8] Ameli F, Brocchetti F, Tosca MA, et al. Tonsil volume and allergic rhinitis in children [J]. Allergy Rhinol(Providence), 2014, 5(3): 137-142.
[9] Chng SY, Goh DY, Wang XS, et al. Snoring and atopic disease: a strong association [J]. Pediatr Pulmonolo, 2004, 38(3): 210-216.
[10] 施俊, 吕静荣, 吴皓. 未合并变应性鼻炎及哮喘的OSAHS儿童血清Th1/Th2细胞因子检测及临床意义 [J]. 临床耳鼻咽喉头颈外科杂志, 2012, 26(23): 1073-1076. SHI Jun, LÜ Jingrong, WU Hao. Th1/Th2 cytokines and its clinical significance in obstructive sleep apnea hypopnea syndrome children without allergic rhinitis and asthma[J]. Clin J Otorhinolarynol Head Neck Surg, 2012, 26(23): 1073-1076.
[11] Kumar RK, Webb DC, Herbert C, et al. Interferon-gamma as a possible target in chronic asthma [J]. Inflamm Allergy Drug Targets, 2006, 5(4): 253-256.
[12] Cao J, Que C, Wang G, et al. Effect of posture on airway resistance in obstructive sleep apnea-hypopnea syndrome by means of impulse oscillation[J]. Respiration, 2009, 77(1): 38-43.
[13] Zhang J, Zhao J, Chen M, et al. Airway resistance and allergic sensitization in children with obstructive sleep apnea hypopnea syndrome [J]. Pediatr Pulmonolo 2016, 51(4): 426-430.
[14] 王丰, 周成勇, 张京红, 等. 儿童OSAHS和变应性鼻炎的关系探讨[J]. 临床耳鼻咽喉头颈外科杂志, 2012, 26(6): 260-262. WANG Feng, ZHOU Chengyong, ZHANG Jinghong, et al. Correlation between allergic rhinitis and childhood obstructive sleep apnea-hypopnea syndrome[J]. Clin J Otorhinolarynol Head Neck Surg, 2012, 26(6): 260-262.
[15] 杨扬, 张杰, 陈敏, 等. 变应性鼻炎对儿童阻塞性睡眠呼吸暂停低通气综合征的影响[J]. 山东大学耳鼻喉眼学报, 2015, 29(3): 6-8. YANG Yang, ZHANG Jie, CHEN Min, et al. Effect of allergic rhinitis on obstructive sleep apnea hypopnea syndrome in children[J]. J Otolaryngol Ophthalmol Shandong Univ, 2015, 29(3): 6-8.
[16] Evcimik MF, Dogru M, Cirik AA, et al. Adenoid hypertrophy in children with allergic disease and influential factors [J]. Int J Pediatr Otorhinolaryngol, 2015, 79(5): 694-697.
[17] Dogru M, Evcimik MF, Calim OF. Does adenoid hypertrophy affect disease severity in children with allergic rhinitis? [J]. Eur Arch Otorhinolaryngol, 2017, 274(1): 209-213.
[18] Friedman M, Maley A, Kelley K, et al. Impact of nasal obstruction on obstructive sleep apnea [J]. Otolaryngol Head Neck Surg, 2011, 144(6): 1000-1004.
[19] Loehrl TA, Smith TL, Darling RJ, et al. Autonomic dysfunction, vasomotor rhinitis, and extraesophageal manifestations of gastroesophageal reflux[J]. Otolaryngol Head Neck Surg, 2002, 126(4): 382-387.
[20] Wu J, Gu M, Chen S, et al. Factors related to pediatric obstructive sleep apnea-hypopnea syndrome in children with attention deficit hyperactivity disorder in different age groups [J]. Medicine, 2017, 96(42): e8281.
[21] Tsai JD, Chen HJ, Ku MS, et al. Association between allergic disease, sleep disordered breathing, and childhood nocturnal enuresis: a population-based case-control study[J]. Pediatr Nephrol, 2017, 32(12):2293-2301.
[22] Zheng M, Wang X, Zhang. LAssociation between allergic and nonallergic rhinitis and obstructive sleep apnea[J]. Curr Opin Allergy Clin Immunol, 2018, 18(1):16-25.
[23] Lee DJ, Chung YJ, Yang YJ, et al. The Impact of Allergic Rhinitis on Symptom Improvement in Pediatric Patients After Adenotonsillectomy[J]. Clin Exp Otorhinolaryngol, 2018, 11(1):52-57.
[24] Kim DK, Han DH. Impact of allergic rhinitis on quality of life after adenotonsillectomy for pediatric sleep-disordered breathing[J]. Int Forum Allergy Rhinol, 2015, 5(8): 741-746.
[25] Tagaya M, Nakata S, Yasuma F, et al. Children with severe or moderate obstructive sleep apnoea syndrome show a high incidence of persistence after adenotonsillectomy[J]. Acta Otolaryngol, 2012, 132(11): 1208-1214.
[26] Zhang Q, Li D, Wang H. Long term outcome of tonsillar regrowth after partial tonsillectomy in children with obstructive sleep apnea [J]. Auris Nasus Larynx, 2014, 41(3): 299-302.
[27] Huo Z, Shi J, Shu Y, et al. The relationship between allergic status and adenotonsillar regrowth: a retrospective research on children after adenotonsillectomy[J]. Sci Rep, 2017, 7:46615.
[28] Marchisio P, Varricchio A, Baggi E, et al. Hypertonic saline is more effective than normal saline in seasonal allergic rhinitis in children[J]. Int J Immunopathol Pharmacol, 2012, 25(3): 721-730.
[29] 岳耀光, 黄合银, 黄丽芳, 等. 舌下含服粉尘螨滴剂治疗儿童变应性鼻炎合并腺样体肥大的疗效观察 [J]. 山东大学耳鼻喉眼学报, 2014, 28(3): 16-19. YUE Yaoguang, HUANG Heyin, HUANG Lifang, et al. Efficacy of specific sublingual immunotherapy with dermatophagoides farinae drops on allergic rhinitis and ade-noid hypertrophy in children[J]. J Otolaryngol Ophthalmol Shandong Univ, 2014, 28(3): 16-19.
[1] LIU Bing, LI Bei, ZHANG Li, CHEN Min, ZHANG Jie. Clinical Analysis of Benign Paroxysmal Vertigo in preschool and school-age children [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 58-60.
[2] XU Ming, LUO Xinggu, TANG Hongbo, JIANG Qingshan. Clinical characteristics and prognostic factors for sudden idiopathic sensorineural hearing loss in children [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 41-44.
[3] QIN Gang, LIANG Zhuoping. Status of immunotherapy in allergic fungal rhinosinusitis [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(3): 23-26.
[4] LIANG Zhengyan, DENG Yuqin, TAO Zezhang. Effect of maternal allergy and environmental exposure on immune maturation [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(3): 96-104.
[5] LIU Dabo. Evaluation of sleep structure disorder in children with obstructive sleep apnea hypopnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 6-8.
[6] LI Yanzhong, ZHANG Tai. Problems we face in children with obstructive sleep apnea hypopnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 1-5.
[7] XU Zhifei, NI Xin. Post-surgery management in children with obstructive sleep apnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 9-13.
[8] QIU Shuyao, LIU Dabo, ZHONG Jianwen, YANG Liqiang. Analysis of coblation complications in children with obstructive sleep apnea-hypopnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 34-37.
[9] ZHONG Jianwen, LIU Dabo, LUO Xiangqian, HUANG Zhenyun, QIU Shuyao, CHENG Chao, YANG Liqiang, YI Xinhua, ZENG Jinhong. The application of wearable devices in the diagnosis of children obstructive sleep apnea [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 30-33.
[10] GAO Jinliang, NIAN Wanqing, LI Shuo. Evaluation of the clinical curative effect of nose surgery in combination with nasal corticosteroids in [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 38-42.
[11] PAN Hongguang, WANG Jumei, CHEN Guowei, WU Zebin. Olfactory function in healthy senior grade students in Shenzhen city. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(3): 71-74.
[12] YIN Juan, HE Yingyao, GUO Heling, XIAO Xuping. Analysis of the long-term clinical effects of different plasma operations on obstructive sleep apnea hypopnea syndrome in children with grade 1 tonsils. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(3): 87-90.
[13] . Relationship between vitamin D and obstructive sleep apnea hypopnea syndrome in children. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(1): 21-26.
[14] YU Qingqing, TANG Jun, WANG Yuejian. A systemic review system to evaluate the effects of different tonsil and adenoid surgical methods on children with obstructive sleep apnea-hypopnea syndrome. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(5): 42-48.
[15] WANG Lei, LOU Feng, ZHANG Yuan, ZHAO Xin. Effect of different doses of dexmedetomidine preoperative intranasal medication on the safety in children tonsillectomy. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(5): 115-119.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] ZHAO Li-min, NI Kun, WU Jia-li, CHEN Shu-mei, LI Xiao-yan. Etiology and treatment of inspiratory laryngeal stridor in infants[J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(2): 49 -51 .
[2] SHI Chun-sheng1, ZHANG Qing-quan2, WANG Qiang2, SUN Yan2, GE Chang-yi1. Application of flaps in the reconstruction of soft palate defects[J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(2): 86 -88 .
[3] ZHANG Ling1, SUN Chuan-yi1, XU An-ting2. 1 case of petrous apex cholesteatoma deafness patients[J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(2): 93 -94 .
[4] . [J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(4): 1 -3 .
[5] LUO Hui-xiu, FAN Chun-tao, DENG Yan-hua. Therapeutic effects of adenoidectomy and tonsillectomy in children with obstructive sleep apnea hypopnea syndrome[J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(4): 17 -20 .
[6] HAO Ying-juan1, YANG Qing-song2, ZHOU Yue-hua2, YI Sheng-ping1, ZHAI Chang-bin2. Characteristics of thin corneal flaps created with Wavelight FS200 femtosecond laser[J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(4): 26 -31 .
[7] WEN Hua-ming1, LI Hai-xiang2. Application of trianglar function method to calculate intra ocular lens power after myopic laser in situ keratomileusis[J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(5): 74 -76 .
[8] ZHU Jian, HE Qing-qing, ZHENG Lu-ming, FAN Zi-yi, ZHAO Guo-wei, HOU Lei, SHI Hou-bin. Clinical analysis for 57 re-operational cases of differentiated thyroid cancer[J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(6): 9 -12 .
[9] LI Shao-hua, SUN Yi-fan, LU Biao-qing. Application of double vascularized soft tissue flap in open radical mastoidectomy[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(1): 6 -7 .
[10] WEI Xi-jian1, YIN Rui-lan2, GUO Xing3. Expression of a proliferation-inducing ligand in laryngeal squamous cell carcinoma[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(1): 14 -16 .