Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2019, Vol. 33 ›› Issue (1): 49-52.doi: 10.6040/j.issn.1673-3770.1.2018.033

• Research Progress • Previous Articles     Next Articles

Advances in interaction mechanisms and treatment strategy between chronic rhinosinusitis with nasal polyp and asthma

Yu ZHANG(),Xicheng SONG*()   

  1. Department of Otorhinolaryngology Head and Neck Surgery, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai 264000, Shandong, China
  • Received:2018-11-06 Online:2019-01-20 Published:2019-01-28
  • Contact: Xicheng SONG E-mail:superzhang013@163.com;songxicheng@126.com

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Abstract:

Chronic rhinosinusitis with nasal polyp (CRSwNP) and asthma are representative chronic inflammatory diseases, which often coexist in the upper and lower airways. It is difficult to perform an effective therapy for patients with CRSwNP accompanied by asthma because interaction mechanisms and therapeutic effects after medical treatment and endoscopic sinus surgery remain unclear. The European position paper on rhinosinusitis and nasal polyps 2012 (EPOS 2012) presents detailed guidelines on the therapy of CRSwNP with or without asthma, including intranasal corticosteroids, nasal irrigation with saline, and so on. In addition, comprehensive follow-up treatments need to be performed according to the feature and severity of symptoms of CRSwNP. Research shows that it is beneficial for improving the prognosis of patients with CRSwNP accompanied by asthma by combining sinus surgery with medical treatment, but further randomized clinical trials are needed to better understand the management of asthma accompanied by CRSwNP.

Key words: Chronic rhinosinusitis with nasal polyp, Asthma, United airways, Pathogenesis, Therapy

CLC Number: 

  • R765.41
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