Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2022, Vol. 36 ›› Issue (4): 17-21.doi: 10.6040/j.issn.1673-3770.0.2021.272
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XU Jia, LI Xin, CHEN Wenjing, GAO Juanjuan, LU Xingxing, YI Haijin
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[1] Sajjadi H, Paparella MM. Meniere's disease [J]. The Lancet, 2008, 372(9636):406-414. doi: 10.1016/S0140-6736(08)61161-7. [2] 侯小兵, 任同力, 张毅博. 69例梅尼埃病伴耳鸣的发病特点及影响因素[J]. 山东大学耳鼻喉眼学报, 2018,32(5): 37-40. doi: 10.6040/j.issn.1673-3770.0.2017.205. HOU Xiaobing, REN Tongli, ZHANG Yibo. Characteristics of tinnitus and the related influencing factors in patients with Meniere's disease[J]. J Otolaryngol Ophthalmol Shandong Univ, 2018,32(5): 37-40. doi: 10.6040/j.issn.1673-3770.0.2017.205. [3] 黄巧, 尹时华. 内耳上皮钠通道、水通道蛋白与内淋巴代谢相关性的研究进展[J]. 山东大学耳鼻喉眼学报, 2019,33(4): 145-148. doi: 10.6040/j.issn.1673-3770.0.2018.301. HUANG Qiao, YIN Shihua. Correlation between endolymphatic Hydrops and inner ear epithelial sodium channels and aquaporins[J]. J Otolaryngol Ophthalmol Shandong Univ, 2019,33(4): 145-148. doi: 10.6040/j.issn.1673-3770.0.2018.301. [4] van Esch BF, van der Zaag-Loonen HJ, Bruintjes TD, et al. Interventions for meniere's disease: Protocol for an umbrella systematic review and a network meta-analysis [J]. BMJ Open, 2016, 6(6):e010269. doi: 10.1136/bmjopen-2015-010269. [5] Kitahara T. Evidence of surgical treatments for intractable meniere's disease [J]. Auris Nasus Larynx, 2018, 45(3): 393-398. doi.org/10.1016/j.anl.2017.07.016. [6] 金昕, 孔维佳, 冷杨名, 等. 梅尼埃病诊断和治疗指南(2017)[J]. 中华耳鼻咽喉头颈外科杂志, 2017, 52(3): 167-172. doi: 10.3760/cma.j.issn.1673-0860.2017.03.002. JIN Xin, KONG Weijia, LING Yangming, et al. Guideline of diagnosis and treatment of meniere disease(2017). Chin J Otorhinolaryngol Head Neck Surg, 2017, 52(3): 167-172. doi: 10.3760/cma.j.issn.1673-0860.2017.03.002. [7] 樊兆民, 张道宫. 内淋巴囊手术[J]. 中国耳鼻咽喉头颈外科, 2015, 22(5): 246-248. doi: 10.16066/j.1672-7002.2015.05.010. FAN Zhaomin, ZHANG Daogong. Endolymphatic sac surgery [J]. Chin Arch Otolaryngol Head Neck Surg, 2015, 22(5):246-248. doi: 10.16066/j.1672-7002.2015.05.010. [8] Lim MY, Zhang M, Yuen HW, et al. Current evidence for endolymphatic sac surgery in the treatment of meniere's disease: A systematic review[J]. Singapore Med J, 2015, 56(11):593-598. doi: 10.11622/smedj.2015166. [9] Sood AJ, Lambert PR, Nguyen SA, et al. Endolymphatic sac surgery for meniere's disease: a systematic review and meta-analysis [J]. Otol Neurotol, 2014,35(6):1033-1045. doi: doi: 10.1097/MAO.0000000000000324. [10] Convert C, Franco-Vidal V, Bebear JP, et al. Outcome-based assessment of endolymphatic sac decompression for ménière's disease using the ménière's disease outcome questionnaire: A review of 90 patients [J]. Otol Neurotol, 2006, 27(5):687-696. doi: 10.1097/01.mao.0000227661.52760.f1. [11] Nevoux J, Barbara M, Dornhoffer J, et al. International consensus(icon)on treatment of meniere's disease [J]. Eur Ann Otorhinolaryngol Head Neck Dis, 2018, 135(1S):S29-S32. doi: https://doi.org/10.1016/j.anorl.2017.12.006. [12] Froehlich MH, Lambert PR. The physiologic role of corticosteroids in meniere's disease: an update on glucocorticoid-mediated pathophysiology and corticosteroid inner ear distribution [J]. Otol Neurotol, 2020, 41(2):271-276. doi: 10.1097/MAO.0000000000002467. [13] Salt AN, Plontke SK. Pharmacokinetic principles in the inner ear: Influence of drug properties on intratympanic applicatio ns [J]. Hear Res, 2018, 368:28-40. doi: 10.1016/j.heares.2018.03.002. [14] Bird PA, Begg EJ, Zhang M, et al. Intratympanic versus intravenous delivery of methylprednisolone to cochlear perilymph [J]. Otol Neurotol, 2007,28(8):1124-1130. doi: 10.1097/MAO.0b013e31815aee21. [15] Lee JJ, Jang JH, Choo OS, et al. Steroid intracochlear distribution differs by administration method: Systemic versus intratympanic in jection [J]. Laryngoscope, 2018,128(1):189-194. doi: 10.1002/lary.26562. [16] Kitahara T, Kubo T, Okumura S, et al. Effects of endolymphatic sac drainage with steroids for intractable meniere's disease: a long-term follow-up and randomized controlled study [J]. Laryngoscope, 2008,118(5):854-861. doi: 10.1097/MLG.0b013e3181651c4a. [17] Sakagami M, Kitahara T, Ito T, et al. Effects of posterior tympanotomy with steroids at round window on hearing recovery after revision surgery for intractable meniere's disease [J]. Acta Otolaryngol, 2015, 135(7):667-672. doi: 10.3109/00016489.2015.1009161. [18] Wick CC, Manzoor NF, McKenna C, et al. Long-term outcomes of endolymphatic sac shunting with local steroids for meniere's disease [J]. Am J Otolaryngol, 2017, 38(3): 285-290. doi: 10.1016/j.amjoto.2017.01.023. |
[1] | YANG Kun, CHEN Lijuan, HE Xiaodan, LIU Zhiqi, SHA Suhua. Comparative study of ototoxicity between kanamycin and 2-hydroxypropyl-β-cyclodextrin [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(4): 6-11. |
[2] | HUANG Lan, GAO WeiOverview,CHEN GanggangGuidance. Research progress on the pathogenesis and clinical characteristics of BPPV secondary to inner ear diseases [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(4): 108-113. |
[3] | MA Ning, CHEN Min, LIU Wei, YANG Yang, SHAO Jianbo, HAO Jinsheng, LIU Bing, ZHANG Xiao, DUAN Xiaomin, ZHANG Qifeng, ZHANG Jie. Clinical characteristics and management of pediatric temporal bone fractures [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(1): 13-19. |
[4] | HU Chunyan, DANG Panhong, ZHANG Rui, FAN Mengyun. Analysis of audiological and imaging characteristics of 149 children with unilateral sensorineural hearing loss [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(1): 31-36. |
[5] | PAN Linlin, KONG LingyiOverview,ZHAI Feng, CHEN JieGuidance. Research progress on auditory risk factors and hearing screening methods among neonates [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(1): 131-137. |
[6] | ZHOU Lamei, JIANG Wen, LIU Wen, QIAO Yuehua. Analysis of factors related to the severity of persistent idiopathic tinnitus [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(6): 70-76. |
[7] | ZHANG YaoyaoOverview,WANG HaitaoGuidance. The application of MRI technology with intratympanic gadolinium injection in the diagnosis and treatment of Meniere's disease [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(6): 101-107. |
[8] | ZHONG Liping, GUAN Xilong, WANG Jingjing, TANG Yong. Intratympanic injections and systemic glucocorticoid treatment for sudden hearing loss: a systematic review and Meta-analysis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(5): 1-10. |
[9] | TAN Yufang, YI Tianhua. Clinical characteristics and prognosis of sudden sensorineural hearing loss in post-irradiated nasopharyngeal carcinoma survivors: a report of 18 cases [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(1): 35-39. |
[10] | JIANG Lina, YU Qianru, YU Jie, GUAN Benling, LU Yu, YU Shudong. Anxiety and depression in patients with common types of vertigo [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(6): 1-5. |
[11] | Vertigo is one of the most important symptom of peripheral vestibular diseases which are difficult to differentially diagnose and manage because multiple disciplines are involved. The premise of effective management is accurate diagnosis of vestibular diseases. With the development of vestibular function examination technology and the deepening of vestibular disease research, great progress has been made in the diagnosis and management of vestibular diseases. The establishment and publication of international classification of vestibular diseases, the introduction of diagnostic standards for various vestibular diseases in the world, the formulation of vestibular disease drugs, surgical specifications and the rapid development of vestibular rehabilitation technology make the diagnosis and management of vestibular diseases more and more standardized and accurate.. Diagnosis and management of peripheral vestibular diseases [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 1-6. |
[12] | To establish a new grade of vestibular function abnormality in patients with Menieres disease(MD)and to preliminarily investigate its clinical significance and correlation with the hearing stage. MethodsClinical data of patients with unilateral intractable MD hospitalized from January to December were retrospectively reviewed. All patients underwent pure-tone audiometry, cervical vestibular-evoked myogenic potential(cVEMP)testing, ocular VEMP(oVEMP)testing, the video head impulse test(vHIT), and the caloric test. Abnormal semicircular canal function was defined as an abnormal vHIT or caloric test result. Abnormal saccule function was defined as an abnormal cVEMP. Abnormal utricle function was defined as an abnormal oVEMP. Vestibular function grade Ⅰ was defined when the utricle, saccule, and semicircular canal were normal. Vestibular function grade Ⅱ was defined when the utricle, saccule, or semicircular canal was abnormal. Vestibular function grade Ⅲ was defined when two structures among the utricle, saccule, and semicircular canal were abnormal. Finally, vestibular function grade Ⅳ was defined when the utricle, saccule, and semicircular canal were all abnormal. ResultsWe enrolled cases of MD, including , , , and cases in stages Ⅰ, Ⅱ, Ⅲ, and Ⅳ, respectively. The pure-tone average(PTA)hearing at Hz, kHz, and kHz was .±. dB HL in the ears with MD. The abnormal rates of cVEMP, oVEMP, vHIT, and caloric test results were .%, .%, .%, and .%, respectively. According to the grade of vestibular function abnormality, , , , and cases were in grades Ⅰ, Ⅱ, Ⅲ, and Ⅳ, respectively. The vestibular function stage significantly correlated with the PTA(Pr=.), MD stage(P., r=.), and disease duration(P=., r=.). The vestibular function stage did not significantly correlate with patient age(P=.). ConclusionThe rates of abnormal otolith and semicircular canal functions increase with the development of MD. Therefore, patients with MD can be accurately assessed with precise testing of the utricle, saccule, and semicircular canals. The status of the development of MD is reflected in the hearing and vestibular function stages. The combined assessment of hearing and vestibular functions can provide a useful reference for the treatment and prognosis of patients with MD.. A new grade of vestibular function abnormality in Menieres disease: a pilot study [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 14-19. |
[13] | To analyze the clinical outcomes of patients with unilateral idiopathic sudden sensorineural hearing loss(SSNHL)and explore the relationship between vestibular function and prognosis in patients with SSNHL. MethodsA retrospective analysis of patients( ears)with SSNHL was performed. A total of vestibular function tests were performed in all patients to assess the influence of vestibular functions on the clinical outcome of SSNHL. ResultsTreatments were less effective in patients with abnormalities in ocular vestibular evoked myogenic potential(oVEMP)or cervical vestibular evoked myogenic potential(cVEMP). Those with normal oVEMP and cVEMP had relatively better hearing recovery. The outcomes of the caloric test or video head impulse test showed no association with the efficacy of treatment or hearing recovery in patients with SSNHL. Treatment was less effective in patients with abnormalities in both oVEMP and cVEMP, who also had worse hearing recovery than those who had an abnormal finding in only one of the two tests. ConclusionsPatients with abnormal oVEMP or cVEMP results had poor clinical outcomes, while those with normal oVEMP and cVEMP demonstrated better hearing recovery with treatment. Thus, oVEMP and cVEMP could be effective indices to predict the prognosis of patients with SSNHL. An abnormal vestibular function is a definite indicator of a wider and more severe pathological change in the inner ear of patients with SSNHL.. Clinical value of vestibular evoked myogenic potential to predict prognosis of unilateral idiopathic sudden sensorineural hearing loss [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 27-32. |
[14] | To analyze the relationship between vestibular symptoms and function and hearing outcomes in patients with unilateral profound sudden sensorineural hearing loss(SSNHL). MethodsA retrospective analysis of patients with unilateral profound SSNHL was performed. Vestibular symptoms and the results of ocular vestibular evoked myogenic potential(oVEMP), cervical vestibular evoked myogenic potential(cVEMP), video head impulse test(vHIT), and caloric test were analyzed to observe the relationship between hearing outcomes and vestibular symptoms and function. ResultsOf patients with unilateral profound SSNHL, there was a significant difference between the patients with and without vestibular symptoms, patients with vestibular dysfunction, and those with normal vestibular function. Patients with abnormal oVEMP, cVEMP, vHIT, and caloric test results showed a lower total effective rate. In contrast, patients with normal results in all four tests had a higher hearing recovery. ConclusionPatients with unilateral profound SSNHL with abnormal vestibular dysfunction and symptoms had a poor curative effect. Conversely, those with normal oVEMP, cVEMP, vHIT, and caloric test results had better chances of hearing recovery. Abnormal vestibular function suggests more extensive and severe inner ear lesions in patients with unilateral profound SSNHL.. Relationship between prognosis and vestibular symptoms/function in patients with unilateral profound sudden sensorineural hearing loss: A retrospective analysis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 33-38. |
[15] | To determine the therapeutic effectiveness of retrolabyrinthine vestibular neurectomy for intractable Menieres disease.MethodsClinical data of patients with unilateral intractable Menieres disease who underwent retrolabyrinthine vestibular neurectomy were retrospectively investigated. Therapeutic effectiveness was analyzed, and the safety and reliability of the procedure was discussed. ResultsThe mean duration of the disease was .±. months. Preoperative pure tone average of Hz, Hz, Hz, and Hz was(.±.)dB HL. Two cases were stage Ⅱ, cases were stage Ⅲ, and cases were stage Ⅳ. Two stage Ⅱ patients were recurrent cases after endolymphatic sac decompression surgery. Intracranial infection in case(.%), cerebrospinal fluid leakage in cases(.%), temporal facial nerve palsy in case(.%), incision infection in cases(.%), and fat liquefaction in cases(.%)were observed postoperatively. There was no case of intracranial hemorrhage or total deafness. Therapeutic effectiveness for relieving vertigo was level A in cases and level B in cases. ConclusionThe therapeutic effectiveness of retrolabyrinthine vestibular neurectomy for intractable Menieres disease is definite. Surgical risk and postoperative complications are controllable, and the quality of life can be significantly improved after surgery.. Therapeutic effectiveness of 75 cases of retrolabyrinthine vestibular neurectomy for intractable Menieres disease [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 46-50. |
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