JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2014, Vol. 28 ›› Issue (5): 7-9.doi: 10.6040/j.issn.1673-3770.0.2014.186

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Changes of blood pressure in severe OSAHS patients with hypertension before and after Uvulopalatopharyngoplasty

WANG Yu-zhi, L Ling-yan, QU Zhe, WANG Xing-jie, ZHOU Xuan-yan   

  1. Department of Otolaryngology & Head and Neck Surgery, Liaocheng Second People's Hospital, Linqing 252600, Shandong, China
  • Received:2014-05-30 Published:2014-10-16

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Abstract: Objective To investigate changes of blood pressure in the patients with severe obstructive sleep apnea hypopnea syndome(OSAHS) complicated with hypertension between before and after uvulopalatopharyngoplasty (UPPP). Methods 32 Patients suffering from severe OSAHS with hypertension were enrolled. All of them have taken oral antihypertensive drugs for more than three years and the blood pressure was poorly controlled. All the 32 patients were treated with modified UPPP. The polysomnograpy(PSG) and 24-hour dynamic blood pressure were monitored before operation and six months after operation. The results were compared. Results ①Six months after modified UPPP, median of apnea/hypopnea index(AHI)/Apnea index(AI)/ microarousal index(MAI)were all decreased obviously( P<0.05). The average SaO2 and lowest SaO2 were higher significantly (all P<0.05).②Six months after modified UPPP, the 24-hour average systolic blood pressure(SBP)/diastolic blood pressure (DBP), daily and nightly average SBP/DBP all were decreased obviously(P<0.05). Conclusion UPPP is good at blood pressure control for the patients with severe OSAHS complicated with hypertension.

Key words: Sleep Apnea, Obstructive, Hypertension, Uvulopalatopharyngoplasty

CLC Number: 

  • R766.7
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