JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2015, Vol. 29 ›› Issue (4): 42-44.doi: 10.6040/j.issn.1673-3770.0.2014.414

Previous Articles     Next Articles

Evidences from clinical epidemiological survey for allergic rhinitis patients complicated by bronchial asthma after tonsillectomy.

WANG Guifeng, FANG Wenhao, PAN Jinbin, WEI Maobin, WANG Xiaojie, LI Yunxia   

  1. Department of Otorhinolaryngology, The 401 st Hospital of Chinese PLA, Qingdao 266100, Shandong, China
  • Received:2014-12-25 Revised:2015-06-11 Online:2015-08-16 Published:2015-08-16

PDF (PC)

487

Abstract: Objective To explore the effect of tonsillectomy on patients with allergic rhinitis complicated with asthma. Methods A survey about allergic rhinitis severity, asthma starting age, disease severity and the medication control by patients themselves who were treated in the department of otorhinolaryngology, the 401 st hospital of PLA from 1990 to 2000 was carried out. Results A total of 1 249 allergic rhinitis patients completed the survey. The patients were divided into two groups: the tonsillectomy group(n=128) and the non-tonsillectomy group(n=1 121). Of the tonsillectomy group, the longitudinal allergic rhinitis rate was 46.88%, coucurrent asthma rate was 32.03%, asthma starting age was (32.4±7.63) years, moderate incidence rate of asthma was 43.9% and remission rate of asthma with drugs was 82.93%. Of the non-tonsillectomy group, the longitudinal allergic rhinitisrate was 18.20%, coucurrent asthma rate was 47.55%, asthma starting age was (19.88±6.39) years, moderate incidence rate of asthma was 43.90% and remission rate of asthma with drugs was 68.10%.The difference was statistically significant between the two groups(all P<0.05). Conclusion The tonsillectomy has a therapeutic effect on allergic rhinitis complicated with asthma.

Key words: Immune response, Allergic rhinitis, Asthma, Tonsil

CLC Number: 

  • R765.21
[1] 中华耳鼻咽喉头颈外科杂志编委会鼻科组, 中华医学会耳鼻咽喉头颈外科学分会鼻科组.变应性鼻炎诊断和治疗指南(2009, 武夷山)[J]. 中华耳鼻咽喉头颈外科杂志, 2009, 44(12):977-978. Nasal Study Group of Editorial Board of the Chinese Journal of Otorhinolaryngology Head and Neck Surgery. Nasal Study Group of Chinese Medical Association of Otorhinolaryngology Head and Neck Surgery. Guidelines of diagnois and treatment for allergic rhinitis(2009, Wuyishan)[J]. Chin J Otorhinolaryngol Head Neck Surg, 2009, 44(12):977-978.
[2] 中华医学会呼吸系分会哮喘学组.支气管哮喘防治指南(支气管哮喘的定义、诊断、治疗和管理方案)[J]. 中华哮喘杂志:电子版, 2008, 2(1):3-13. Asthma Group of the Respiratory Disease Branch of Chinese Medical Association. Guidelines for the prevention and treatment of bronchial asthma: the definition, dianosis, treatment and management program[J]. Chin J Asth, 2008, 2(1):3-13.
[3] Bhattacharjee R, Choi B H, Gozal D, et al. Associaton of adenotonsillectomy with asthma outcomes in children: a longitudinal database anslysis[J]. PLOS Med, 2014, 11(1):1-12.
[4] 韩德民. 鼻部疾病和支气管哮喘[J]. 哮喘杂志, 2000, 6(1):53-57. HAN Demin. Nasal disease and bronchial asthma[J]. Asthma, 2000, 6(1):53-57.
[5] Togias A. Rhinitis and asthma:evidence for respiratory system integtation[J]. J Allergy Clin Immunol, 2003, 111(6):1171-1184.
[6] 文昭明. 呼吸系统变态反应疾病诊断治疗学[M]. 北京:中国协和医科大学出版社, 2002: 2-3.
[7] 张金花, 周怡, 刘宇. 内源性哮喘免疫支持治疗的探讨[J]. 中国现代医学杂志, 2007, 17(4):464-466. ZHANG Jinhua, ZHOU Yi, LIU Yu. Discussion of immutherapy to patients with intrinsic asthma[J]. Chin J Modern Med, 2007, 17(4):464-466.
[8] 杨珍, 张莉. 扁桃体免疫功能研究进展[J]. 内蒙古医学院学报, 2006, 28(3):240-242. YANG Zhen, ZHANG Li . The research progress of immune function of the tonsils[J]. Acta Acad Med Neimongol, 2006, 28(3):240-242.
[9] 闵密克, 陈丽华, 金伯泉, 等. 腭扁桃体中几种杀伤功能相关分子的表达[J]. 临床军医杂志, 2010, 38(5):785-787. MIN Mike, CHEN Lihua, JIN Boquan, et al. Expression and distribution of several cytotoxicity associated molecules in palatine tonsil[J]. Clin J Med Off, 2010, 38(5):785-787.
[10] 张涛, 丁勇, 王继群, 等. 扁桃体组织中白细胞介素-4的表达和意义[J]. 中国病理生理杂志, 2000, 16(2):112-114. ZHANG Tao, DING Yong, WANG Jiqun, et al. The expression and effect of IL-4 in human palatine tonsil[J]. Chin J Pathophysiol, 2000, 16(2):112-114.
[11] 杨珍. 扁桃体组织中IL- 4与 IL- 5的表达和意义[J]. 内蒙古医学杂志, 2011, 33(4):322-324. YANG Zhen. The clinical significance of expressions of IL-4 and IL-5 in palatine tonsil[J]. Inner Mongolia Med J, 2011, 33(4):322-324.
[12] 罗蓉, 孔维佳, 黄翔, 等. 慢性扁桃体炎患者外周血T淋巴细胞亚群的分析与临床意义[J].临床耳鼻咽喉头颈外科杂志, 2009, 23(10):436-442. LUO Rong, KONG Weijia, HUANG Xiang, et al. Peripheral T cell subsets in chronic tonsillitis patients[J]. J Clin Otorhinolaryngol Head Neck Surg, 2009, 23(10):436-442.
[13] 黄宇勇, 黄晓华, 徐浩文. 手术治疗对慢性扁桃体炎患者细胞免疫功能的影响[J].临床耳鼻咽喉头颈外科杂志, 2011, 25(4):182-183. HUANG Yuyong, HUANG Xiaohua, XU Haowen. Operation treatment effect on immune cells in patients with chronic tonsillitis function[J]. Clin Otolaryngol Head Neck Surg, 2011, 25(4):182-183.
[14] 杨勇, 陈宗波. 反复扁桃体炎患儿缓解期T细胞亚群及辅助性T淋巴细胞亚群的功能状态[J].实用儿科临床杂志, 2006, 21(4):222-223. YANG Yong, CHEN Zongbo. Study on T- cell and T- helper cell subpopulation function in children with recurrent tonsillitis in remission period[J]. J App Clin Pedia, 2006, 21(4):222-223.
[1] WANG Tan, WU Ke, LI Lianqing, GONG Lili. Factors associated with systemic adverse reactions after subcutaneous immunotherapy injections and treatment options [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 71-74.
[2] LU Hangui, LIN Xinsheng, YAO Danmian, WEI Yongxin, LI Chuangwei. Expression of IL-35 in allergic rhinitis and its effect on the immunoregulation of T cells [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 66-70.
[3] PU Hongbo, DU Xiaodong. Allergen test results in 2 000 patients with allergic rhinitis in Wuxi District [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(4): 105-107.
[4] CHEN Ming, YU Xuefei. Opinions on the treatment of chronic rhinosinusitis with allergic rhinitis [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(3): 18-22.
[5] WU Xiangping. Influence of patient management on the clinical effect of sublingual dermatophagoides farinae drops in patients [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(3): 68-72.
[6] XU Zhifei, NI Xin. Post-surgery management in children with obstructive sleep apnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 9-13.
[7] WANG Yan, SHI Xiaoli. The relationship between allergic reaction and children obstructive sleep apnea hypopnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 14-18.
[8] LIU Jie, QU Hui, LU Daowen, XIN Huaxiu, GUO Yanli. Spring pollinosis in Qingdao west district [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 70-72.
[9] LI Yanzhong, ZHANG Tai. Problems we face in children with obstructive sleep apnea hypopnea syndrome [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 1-5.
[10] LI Song, WANG Zonggui, YANG Jingpu, ZHANG Zhuping. Progress of transnasal endoscopic vidian neurectomy [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(1): 72-76.
[11] ZHANG Liqing, SONG Shenghua, WANG Yuan, LIU Xiaojing, DONG Weida, ZHOU Han. Comparison of the efficacy of coblation, ultrasonic knife operation, and conventional tonsillectomy in a 2-year postoperative follow-up. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(5): 67-71.
[12] ZHANG Jie, CHEN Xuemei, XU Anting. A comparative analysis of harmonic scalpel tonsillectomy and coblation tonsillectomy. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(5): 95-100.
[13] ZHI Lili, SONG Daoliang. Expressions of eosinophils and IL5 in antrochoanal polyps and nasal polyps. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(4): 43-46.
[14] WAN Wenjin, WANG Wen, CHENG Lei. A meta-analysis of subcutaneous immunotherapy and sublingual immunotherapy in the treatment of dust mite-allergic rhinitis. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(4): 103-108.
[15] SHI Li, ZHAO Li, ZHANG Hongping. Long-term anti-inflammatory treatment of allergic rhinitis. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(3): 9-12.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd