Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2018, Vol. 32 ›› Issue (6): 13-17.doi: 10.6040/j.issn.1673-3770.1.2018.025

• Original Articles • Previous Articles     Next Articles

Evaluate the curative effect of CO2 laser in treatment of laryngeal carcinoma

Wenming LI,Dongmin WEI,Ye QIAN,Shengda CAO,Ya XU,Dayu LIU,Xinliang PAN,Dapeng LEI*()   

  1. Department of Otorhinolaryngology, Qilu Hospital of Shandong University, NHC Key Laboratory of Otorhinolaryngology, Jinan 250012, Shandong, China
  • Received:2018-10-15 Online:2018-11-20 Published:2018-11-29
  • Contact: Dapeng LEI E-mail:leidapeng@sdu.edu.cn

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Abstract: Objective

To evaluate the curative effect of CO2 laser in the treatment of laryngeal carcinoma.

Methods

A retrospective analysis of 152 cases of early laryngeal carcinoma treated with laser surgery between 2011 and 2014 was conducted. Among all cases, 11, 102, 31, and 8 were Tis, T1a, T1b, and T2 cases, respectively.

Results

After the CO2 laser treatment, patients were discharged within 1-3 days. There were no complications, such as dyspnea and tracheotomy, during the perioperative period. The long-term pronunciation quality was satisfactory. The follow-up period was 4-8 years. The recurrence rate of glottic carcinoma was 8.2% (147 cases). Two patients had salvage surgery with CO2 laser. Six patients had salvage partial laryngectomy and four cases total laryngectomy. The five-year overall survival rate was 96.6%. Five cases of supraglottic carcinoma were followed up for 5 years without recurrence.

Conclusion

CO2 laser surgery is a minimally invasive, effective, and safe procedure for early laryngeal carcinoma. Satisfactory exposure, good surgical skills, and appropriate surgical indications are fundamental for the success of CO2 laser treatment.

Key words: Laryngeal carcinoma, CO2 laser, Carcinoma, squamous cell

CLC Number: 

  • R767

Fig.1

Flesh plaque hyperplasia and scar evolution after surgery A: Preoperative laryngoscope; B: One month post-surgery, granulation hyperplasia in the operation area can be seen; C: Granulation resolved and scars formed 3-month post-surgery. "

Table 1

Survival rates after laryngeal cancer laser surgery for different stages of tumor[%(n)]"

分期 n 3年生存率 5年生存率
声门型Tis 11 100.0(11/11) 100.0(11/11)
声门型T1a 97 100.0(97/97) 97.9(95/97)
声门型T1b 31 100.0(31/31) 93.5(29/31)
声门型T2 8 100.0(8/8) 87.5(7/8)
声门上型T1 5 100.0(5/5) 100.0(5/5)
合计 152 100.0(152/152) 96.7(147/152)
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