Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2019, Vol. 33 ›› Issue (4): 47-51.doi: 10.6040/j.issn.1673-3770.0.2018.573

Previous Articles     Next Articles

Correlation between unilateral sudden deafness and imaging features of vertebrobasilar artery

ZHAO Junying, WANG Jianming   

  1. Department of Otorhinolaryngology Head Neck Surgery, The First Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China
  • Online:2019-07-20 Published:2019-07-22

PDF (PC)

285

Abstract: Objective To investigate the correlation between unilateral sudden deafness and the imaging features of vertebrobasilar artery. Methods This study included 175 patients diagnosed with unilateral sudden deafness in our hospital between 2014 and 2018, who had complete laboratory and imaging data. Data were analyzed in order to determine the relationship between the side and degree of hearing loss and the imaging characteristics of vertebral and basilar arteries. Results A stenosis/tortuosity of vertebral(χ2=8.031, P=0.045)and basilar arteries(χ2=5.091, P=0.034)was found to be related to hearing loss side. The univariate analysis results of hearing loss predictors demonstrated that left-sided hearing loss in patients is related to right-sided(odds ratio ［OR］=2.89, 95% confidence interval ［CI］: 1.77-2.77, P=0.036)and bilateral vertebral artery stenosis/tortuosity(OR=4.43, 95% CI: 1.49-13.23, P=0.008). Basilar artery stenosis/tortuosity on neither side is related to right-sided hearing loss in patients(OR=0.31, 95% CI: 0.11-0.90, P=0.030). Other evaluated factors were not statistically significant. Multivariate analysis matched by age and sex demonstrated that stenosis/tortuosity of the right vertebral artery was related to left-sided hearing loss(OR=2.83, 95% CI: 1.05-7.67, P=0.040), whereas no statistically significant difference was observed for the relationship between stenosis/tortuosity of basilar artery and hearing loss(χ2 = 3.339, P=0.068). The degree of hearing loss in patients with sudden deafness is not related with the imaging features of the vertebral(χ2 = 3.897, P=0.273)and basilar arteries(χ2 = 3.339, P=0.068). Conclusion In patients with sudden deafness, the lateral nature of hearing loss is influenced by stenosis/tortuosity of the vertebrobasilar artery, whereas stenosis/tortuosity of the right vertebral artery is related to hearing loss in the left ear.

Key words: Sudden deafness, Vertebrobasilar artery, Posterior circulation ischemia, Etiology

CLC Number: 

  • R764.13
[1] 中华耳鼻咽喉头颈外科杂志编辑委员会[J]. 中华医学会耳鼻咽喉头颈外科学分会. 突发性聋诊断和治疗指南(2015)[J]. 2015, 50(6): 443-447. doi:10.3760/cma.j.issn.1673-0860.2015.06.002.
[2] Wei BP, Stathopoulos D, O'Leary S. Steroids for idiopathic sudden sensorineural hearing loss. Jama the Journal of the American Medical Association, 2011, 305(20): 2114-5. doi:10.1002/14651858.cd003998.pub2.
[3] Kim C, Sohn JH, Choi HC. Vertebrobasilar angulation and its association with sudden sensorineural hearing loss[J]. Medical Hypotheses, 2012, 79(2): 202-203. doi:10.1016/j.mehy.2012.04.035.
[4] Kim C, Sohn JH, Jang MU, et al. Ischemia as a potential etiologic factor in idiopathic unilateral sudden sensorineural hearing loss: Analysis of posterior circulation arteries[J]. Hearing Research, 2016, 331: 144-151. doi:10.1016/j.heares.2015.09.003.
[5] Lin C, Lin SW, Lin YS, et al. Sudden sensorineural hearing loss is correlated with an increased risk of acute myocardial infarction: A population-based cohort study[J]. Laryngoscope, 2013, 123(9):2254-2258. doi: 10.1002/lary.23837.
[6] Lee H. Recent advances in acute hearing loss due to posterior circulation ischemic stroke[J]. Journal of the Neurological Sciences, 2014, 338(1/2): 23-29. doi:10.1016/j.jns.2013.12.048.
[7] 艾伟, 孔维佳. 氧自由基对豚鼠耳蜗微血管内皮细胞凋亡的影响及其机制[J]. 华中科技大学学报(医学版), 2009, 38(3): 359-363. doi:10.3870/j.issn.1672-0741.2009.03.019. AI Wei, KONG Weijia. Effects of oxygen free radical on apoptosis in cochlea microvascular endothelial cells of guinea pigs and the underlying mechanism[J]. Acta Medicinae Universitatis Science of Technologiae Huazhong, 2009, 38(3): 359-363. doi:10.3870/j.issn.1672-0741.2009.03.019.
[8] Lee H. Neuro-otological aspects of cerebellar stroke syndrome[J]. J Clin Neurol, 2009, 5(2): 65. doi:10.3988/jcn.2009.5.2.65.
[9] 翁秋燕, 胡兴越. 后循环缺血的临床及影像学特点探讨[J]. 中华临床医师杂志(电子版), 2010, 4(9): 1717-1719. doi:10.3969/cma.j.issn.1674-0785.2010.09.070.
[10] Hong JM, Chung CS, Bang OY, et al. Vertebral artery dominance contributes to basilar artery curvature and peri-vertebrobasilar junctional infarcts[J]. Journal of Neurology, Neurosurgery & Psychiatry, 2009, 80(10): 1087-1092. doi:10.1136/jnnp.2008.169805.
[11] Chuang YM, Chern CM, Liao WH, et al. Contribution of intracranial vertebral artery asymmetry to vestibular neuropathy[J]. Journal of Neurology, Neurosurgery & Psychiatry, 2011, 82(7): 823-825. doi:10.1136/jnnp.2009.203323.
[12] Dai Y, Lu L, Hou J, et al. Intratympanic methylprednisolone perfusion as a salvage treatment for profound idiopathic sudden sensorineural hearing loss[J]. J Laryngol Otol, 2017, 131(5): 404-410. doi:10.1017/s0022215117000548.
[13] Hsu YH, Hu HY, Chiu YC, et al. Association of sudden sensorineural hearing loss with vertebrobasilar insufficiency[J]. JAMA Otolaryngol Head Neck Surg, 2016, 142(7): 672. doi:10.1001/jamaoto.2016.0845.
[14] Ryu OH, Choi MG, Park CH, et al. Hyperglycemia as a potential prognostic factor of idiopathic sudden sensorineural hearing loss[J]. Otolaryngol Head Neck Surg, 2014, 150(5):853-858. doi: 10.1177/0194599814521012.
[15] Lee H, Baloh RW. Sudden deafness in vertebrobasilar ischemia: clinical features, vascular topographical patterns and long-term outcome[J]. Journal of the Neurological Sciences, 2005, 228(1): 99-104. doi:10.1016/j.jns.2004.10.016.
[16] Quaranta N, Squeo V, Sangineto M, et al. High total cholesterol in peripheral blood correlates with poorer hearing recovery in idiopathic sudden sensorineural hearing loss[J]. PLoS One, 2015, 10(7): e0133300. doi:10.1371/journal.pone.0133300.
[17] Hademenos GJ, Massoud TF. Biophysical mechanisms of stroke[J]. Stroke, 1997, 28(10): 2067-2077. doi:10.1161/01.str.28.10.2067.
[18] 陈伟, 胡中南, 童钊君, 等. 青中年无眩晕、心脑血管疾病病史的突发性聋患者高刺激率听性脑干反应特征分析[J]. 山东大学耳鼻喉眼学报, 2018, 32(5): 45-49. doi:10.6040/j.issn.1673-3770.0.2017.521. CHEN Wei, HU Zhongnan, TONG Zhaojun, et al. Characteristics of auditory brainstem response to high-frequency stimulus in young and middle-aged patients with sudden deafness and no history of vertigo or cardiocerebrovascular disease[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2018, 32(5): 45-49. doi:10.6040/j.issn.1673-3770.0.2017.521.
[1] SHEN Yupeng, SONG Qi, LI Xiaoming. Etiology, molecular mechanisms, and treatment strategies of precancerous laryngeal lesions [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(4): 25-30.
[2] ZHONG Xiaosheng, YANG Haidi, ZHENG Yiqing. Treatment and outcome of tinnitus in sudden deafness [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(4): 43-46.
[3] ZHANG Junjun, LIU Haili, LIU Jiafu, QIN Xiaofeng, DU Hongming, WANG Houhui. Clinical efficacy and safety of different methods of administration of glucocorticoids in the treatment of sudden deafness [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(4): 52-55.
[4] TONG Qiaozhen, ZHAO Yan, CHENG Sihua. The constructive and mediating effects of knowledge/attitude/belief/practice interference on negative emotion in patients with sudden deafness [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(4): 162-164.
[5] WANG Yue, LIU Qian, WANG Haibo. Prospect and progress of spontaneous cerebrospinal fluid otorrhea [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(2): 130-135.
[6] SUN Ziwen, CUI Hongwei, SUN Xiling, CHEN Chen, ZHANG Lu, HU Zhulin. SUN Ziwen1, CUI Hongwei2, SUN XilingEtiology, pathogenesis, and management of dry eye [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(2): 159-166.
[7] Chuangli HAO,Wenjing GU. Recognizing the etiology of chronic cough in children of different ages [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 20-24.
[8] CHEN Wei, HU Zhongnan, TONG Zhaojun, LI Xiangyu, LIU Wenjun. Characteristics of auditory brainstem response to high-frequency stimulus in young and middle-aged patients with sudden deafness and no history of vertigo or cardiocerebrovascular disease [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 45-49.
[9] YAN Huiqin, WANG Hao. Clinical analysis of intractable benign paroxysmal positional vertigo [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(3): 86-88.
[10] ZHANG Yubo, YUE Liyan, YIN Xiaoyan, LÜ Zhe, SHAN Chunguang. Effect of tinnitus treatment instrument combined with Ginkgo biloba extract on hearing and hemorheology in patients with sudden deafness and tinnitus. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(5): 50-53.
[11] . Causes of non-traumatic vitreous hemorrhage and effects of surgical treatment. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(1): 107-109.
[12] ZHU Jiangbin, NAN Bingwei, CHEN Tao, HAO Zongsheng. Treatment of residual tinnitus after threshold recovery of low frequency sudden deafness: a report of 129 cases. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(6): 5-7.
[13] LIU Dingrong, SHI Yuyong, ZHAN Xianjin, LIU Guiling, LIAO Xinchun,YANG Ji, LUO Zehui, LUO Yonghua, LIAO Kuan, WU Ke. Computed tomographic analysis of the relationship between nasal structure and fungal maxillary inflammation. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(5): 94-97.
[14] WANG Yan. Progress in the classification and treatment of sleep respiratory diseases in children. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(5): 5-8.
[15] MA Rongfeng, ZHU Fugao, SUN Meihong, FU Tao, ZHANG Xiaoheng, CAO Lin. Analysis on the relevant prognostic factors of sudden deafness and selection of course of treatment. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(4): 69-74.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2006, 20(2): 116 -118 .
[2] ZHOU Zi-ning,JIN Guo-wei . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2006, 20(5): 462 -465 .
[3] ZHOU Bin,LI Bin . Endoscopic sinus surgery for 75 patients with chronic sinusitis and nasal polyps[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2006, 20(1): 24 -26 .
[4] XU Sainan,YANG Lei . Apoptosis of epithelial cells in nasal polyps promoted by erythromycin[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2006, 20(1): 27 -29 .
[5] . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 200 -203 .
[6] WANG Xiao-feng,LIN Chang,CHENG Jin-mei . Expression of ABAD in inner ears and its clinical significance in different age mice[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 207 -211 .
[7] FAN Qi-jun,HUANG Zhi-wu,MEI Ling,XIAO Bo-kui . Expression of the heat shock protein 27 in rat cochlea induced by sodium salicylate injection by the FQ-PCR technique[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 212 -214 .
[8] . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 227 -227 .
[9] LIN Feng,LIANG Yong,LU Yong-tian,WAN Li-xia . Classification and surgical treatment for nasal inverted papilloma[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 231 -233 .
[10] PANG Tai-zhong,LIU Bing, CHENG Liang-jun . Septum corrective treatment for allergic rhinitis [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 237 -238 .
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd