Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2019, Vol. 33 ›› Issue (4): 43-46.doi: 10.6040/j.issn.1673-3770.0.2018.393

• Original Article • Previous Articles     Next Articles

Treatment and outcome of tinnitus in sudden deafness

Xiaosheng ZHONG1,Haidi YANG2,Yiqing ZHENG2,*()   

  1. 1. Department of Otolaryngology, Zengcheng People′s Hospital, Guangzhou 511300, Guangdong, China
    2. Department of Otolaryngology, Sun Yat-sen Memorial Hospital, Zhongshan University, Guangzhou 511300, Guangdong, China
  • Received:2018-08-29 Online:2019-07-16 Published:2019-07-22
  • Contact: Yiqing ZHENG E-mail:zhengyiq@mail.sysu.edu.cn

Abstract: Objective

To study and analyze the treatment and outcome of tinnitus in sudden deafness with tinnitus.

Methods

Seventy-six cases of sudden deafness with tinnitus were selected and treated according to the Guidelines for Diagnosis and Treatment of Sudden Deafness (2015). After 2 weeks, the tinnitus disability scale (THI) and visual analog scale (VAS) scores were analyzed. All patients were provided psychological counseling at discharge. Individualized short-term medication, masking therapy, acclimatization therapy, and hearing aid therapy were provided to those who could not adapt to tinnitus. At the 1-year follow-up, patients who still experienced tinnitus were treated with masking therapy or acclimatization.

Result

Before and after 2 weeks of routine treatment, the THI scores of the 76 patients were 49.71±2.69 and 41.04±2.84, respectively (t=3.935, P < 0.001); VAS scores were 5.17±0.20 and 4.22±0.25, respectively (t=5.010, P < 0.001). Hearing was good in 53 cases and poor in 23 cases. The difference in THI before and after routine treatment in the good and poor hearing groups was 13.57±2.27 and -2.60±4.28, respectively (t=3.339, P=0.002); the VAS difference before and after routine treatment in the good and poor hearing groups was 1.35±0.17 and 0±0.43, respectively (t=2.953, P=0.006). After psychological counseling, patients were followed up for 1 year by telephone. Of these, 53 patients had adapted to tinnitus, accounting for 69.7% of patients. Twenty-three patients returned to hospital due to tinnitus, accounting for 30.3% of patients. The THI scores ranged between 18 and 92 with an average of 56.6, a mean mostly driven by scores in 3-4 patients with severe tinnitus. The VAS scores at 2 weeks and 1 year were 4.22±0.25 and 3.39±0.18, respectively. There was a significant difference in VAS scores between the two time periods (t=6.362, P < 0.001). After treatment for 2 weeks, tinnitus resolved in four patients and was significantly alleviated in seven patients, alleviated in 11 patients, unchanged in 49 patients, and aggravated in five patients. Tinnitus was reduced by 28.9%. After one year of treatment, tinnitus resolved in six patients and was significantly alleviated in 10 patients, alleviated in 14 patients, unchanged in 42 patients, and aggravated in four patients. In total, for 39.5% of patients, tinnitus was alleviated. After treatment for 2 weeks and 1 year later, there was a significant difference in the rate of tinnitus relief, (χ2=43.978, P < 0.001). After 1 year, 31 patients were completely adapted to tinnitus, and 40 patients were largely adapted; the total adaptation rate was 92.1%. Six patients found it difficult to adapt.

Conclusion

Routine treatment, psychological counseling, masking therapy, and acclimatization therapy for sudden deafness have positive effects on tinnitus. Patients with tinnitus recovered well after individualized treatment.

Key words: Sudden deafness, Tinnitus, Treatment, Outcome

CLC Number: 

  • R764.437
1 中华耳鼻咽喉头颈外科杂志编辑委员会, 中华医学会耳鼻咽喉头颈外科学分会. 突发性聋的诊断和治疗指南(2015)[J]. 中华耳鼻咽喉头颈外科杂志, 2015, 50 (6): 443- 447.
doi: 10.3760/cma.j.issn.1673-0860.2015.06.002
Editorial Committee of Chinese Journal of Otolaryngology Head and Neck Surgery , Society of Otolaryngology Head and Neck Surgery, Chinese Medical Association . Guidelines for Diagnosis and Treatment of Sudden Deafness (2015)[J]. Chin J Otolaryngol Head Neck Surg, 2015, 50 (6): 443- 447.
doi: 10.3760/cma.j.issn.1673-0860.2015.06.002
2 中国突发性聋多中心临床研究协作组. 中国突发性聋分型治疗的多中心临床研究[J]. 中华耳鼻咽喉头颈外科杂志, 2013, 48 (5): 355- 361.
doi: 10.3760/cma.j.issn.1673-0860.2013.05.002
Chinese sudden hearing loss multi-center clinical study group Corresponding . Prospective clinical multi-center study on the treatment of sudden deafness with difterent typings in China[J]. Chin J Otolaryngol Head Neck Surg, 2013, 48 (5): 355- 361.
doi: 10.3760/cma.j.issn.1673-0860.2013.05.002
3 余力生, 马鑫. 耳鸣的代偿与失代偿[J]. 中华耳鼻咽喉头颈外科杂志, 2017, 52 (8): 630- 633.
doi: 10.3760/cma.j.issn.1673-0860.2017.08.019
YU Lisheng , MA Xin . Compensation and decompensation of tinnitus[J]. Chin J Otolaryngol Head Neck Surg, 2017, 52 (8): 630- 633.
doi: 10.3760/cma.j.issn.1673-0860.2017.08.019
4 陈秋坚, 郑亿庆, 邱泽恒, 等. 伴感音神经性聋耳鸣的心理声学和听力学特征[J]. 临床耳鼻咽喉头颈外科杂志, 2012, 26 (10): 449- 451.
CHEN Qiujian , ZHENG Yiqing , QIU Zeheng , et al. Analysis of psychoacoustic characteristics and audiology tests of tinnitus patients with sensorineural hearing loss[J]. J Clin Otolaryngol Head Neck Surg, 2012, 26 (10): 449- 451.
5 乔晓. 耳鸣发病机制及临床分析[J]. 中华现代眼耳鼻喉科杂志, 2006, 3 (4): 333- 341.
QIAO Xiao . Pathogenesis and clinical analysis of tinnitus[J]. Chin J Modern Eye Nose Throat, 2006, 3 (4): 333- 341.
6 Jastreboff PJ , Gray WC , Gold SL . Neurophysiological approach to tinnitus patients[J]. Am J Otol, 1996, 17 (2): 236- 240.
7 杨海弟, 郑亿庆, 张志钢, 等. 主观性耳鸣的掩蔽及习服治疗效果分析[J]. 临床耳鼻咽喉头颈外科杂志, 2010, 24 (10): 442- 446.
YANG Haidi , ZHENG Yiqing , ZHANG Zhigang , et al. Analysis and comparison of the masking and TRT for patiens with subjective tinnitus[J]. J Clin Otolaryngol Head Neck Surg, 2010, 24 (10): 442- 446.
8 Newman CW , Sandridge SA , Bolek L . Development and psychometric adequacy of the screening versin of the tinitus hadicap inventory[J]. Otol Neurotol, 2008, 29 (3): 276- 281.
doi: 10.1097/MAO.0b013e31816569c4
9 钟晓声, 杨海弟, 郑亿庆. 突发性聋伴耳鸣患者耳鸣特征[J]. 山东大学耳鼻喉眼学报, 2015, 29 (4): 15- 18.
doi: 10.6040/j.issn.1673-3770.0.2015.126
ZHONG Xiaosheng , YANG Haidi , ZHENG Yiqing . Characteristics of tinnitus in patients with sudden sensorineural hearing loss[J]. J Otolaryngol Ophthalmol Shandong Univ, 2015, 29 (4): 15- 18.
doi: 10.6040/j.issn.1673-3770.0.2015.126
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