Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2021, Vol. 35 ›› Issue (4): 96-100.doi: 10.6040/j.issn.1673-3770.0.2020.330

Previous Articles     Next Articles

Progress in the surgical treatment of recurrent laryngeal papillomatosis

NIU Zijie, XIAO Yang,WANG Jun,MA Lijinng   

  1. Department of Otolaryngology-Head and Neck Surgery, Bejing Tongren Hospital, Capital Medical University / Key Laboratory of Otolaryngology-Head and Neck Surgery, Capital Medical University, Ministry of Education, Beijing 100730, China
  • Published:2021-08-05

PDF (PC)

719

Abstract: The treatment of laryngeal papilloma is challenging for otolaryngologists. Administering the appropriate treatment can reduce the recurrence rate and the incidence of complications and improve the quality of life of patients. Laryngeal papilloma is the most common benign tumor of the larynx and the common cause of hoarseness in children. Because of recurrence, laryngeal papilloma requires multiple surgeries, and this places psychological and economic burdens on children and their families. In this paper, the common surgical methods and treatment approaches are reviewed to guide the selection of surgical methods by clinicians.

Key words: Laryngeal papillomatosis, Hoarseness, Human papillomavirus, CO2 laser, Microdebrider, Leonardo Da Vinci surgical robot, Low-temperature plasma radio-frequency ablation system

CLC Number: 

  • R739.65
[1] Seedat RY, Schall R. Age of diagnosis, incidence and prevalence of recurrent respiratory papillomatosis: a South African perspective[J]. Clin Otolaryngol, 2018, 43(2): 533-537. doi:10.1111/coa.13016.
[2] San Giorgi MRM, van den Heuvel ER, Tjon Pian Gi REA, et al. Age of onset of recurrent respiratory papillomatosis: a distribution analysis[J]. Clin Otolaryngol, 2016, 41(5): 448-453. doi:10.1111/coa.12565.
[3] Lawlor C, Balakrishnan K, Bottero S, et al. International Pediatric Otolaryngology Group(IPOG): Juvenile-onset recurrent respiratory papillomatosis consensus recommendations[J]. Int J Pediatr Otorhinolaryngol, 2020, 128: 109697. doi:10.1016/j.ijporl.2019.109697.
[4] Seedat RY. Juvenile-onset recurrent respiratory papillomatosis diagnosis and management-A developing country review[J]. Pediatric Health Med Ther, 2020, 11: 39-46. doi:10.2147/phmt.s200186.
[5] 孙睿杰, 许风雷, 刘大昱, 等. 显微支撑喉镜下CO2激光手术或联合干扰素治疗复发性小儿喉乳头状瘤疗效对比[J]. 山东大学耳鼻喉眼学报, 2012, 26(6): 23-25. doi:10.6040/j.issn.1673-3770.2012.06.008. SUN Ruijie, XU Fenglei, LIU Dayu, et al. Effect of CO2 laser surgery combined with interferon on recurrent juvenile laryngeal papillomatosis[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2012, 26(6): 23-25. doi:10.6040/j.issn.1673-3770.2012.06.008.
[6] Novakovic D, Cheng ATL, Zurynski Y, et al. A prospective study of the incidence of juvenile-onset recurrent respiratory papillomatosis after implementation of a national HPV vaccination program[J]. J Infect Dis, 2018, 217(2): 208-212. doi:10.1093/infdis/jix498.
[7] Yan Y, Olszewski AE, Hoffman MR, et al. Use of lasers in laryngeal surgery[J]. J Voice, 2010, 24(1): 102-109. doi:10.1016/j.jvoice.2008.09.006.
[8] Papaioannou VA, Lux A, Voigt-Zimmermann S, et al. Treatment outcomes of recurrent respiratory papillomatosis: Retrospective analysis of juvenile and adult cases[J]. HNO, 2018, 66(suppl 1): 7-15. doi:10.1007/s00106-017-0378-0.
[9] Xu W, Han D, Hou L, et al. Voice function following CO2 laser microsurgery for precancerous and early-stage glottic carcinoma[J]. Acta Otolaryngol, 2007, 127(6): 637-641. doi:10.1080/00016480600987776.
[10] Ivancic R, Iqbal H, DeSilva B, et al. Current and future management of recurrent respiratory papillomatosis[J]. Laryngoscope Investig Otolaryngol, 2018, 3(1): 22-34. doi:10.1002/lio2.132.
[11] Preciado DA. Hemostasis in airway surgery[J]. Otolaryngol Clin N Am, 2016, 49(3): 691-703. doi:10.1016/j.otc.2016.02.007.
[12] Rasmussen ER, Schnack DT, Jørkov AS, et al. Long-term follow-up and outcome in patients with recurrent respiratory laryngeal papillomatosis [J]. Danish Medical Journal, 2017, 64(12): A5424.
[13] Scatolini ML, Labedz G, Cocciaglia A, et al. Laryngeal sequelae secondary to surgical treatment for recurrent respiratory papillomatosis in children[J]. Int J Pediatr Otorhinolaryngol, 2020, 130: 109815. doi:10.1016/j.ijporl.2019.109815.
[14] Holler T, Allegro J, Chadha NK, et al. Voice outcomes following repeated surgical resection of laryngeal papillomata in children[J]. Otolaryngol Head Neck Surg, 2009, 141(4): 522-526. doi:10.1016/j.otohns.2009.06.080.
[15] 杨庆文, 徐文, 郭伟, 等. CO2激光结合显微电动吸切器治疗重症幼年型复发性呼吸道乳头状瘤回顾性分析[J]. 中华耳鼻咽喉头颈外科杂志, 2017, 52(10): 733-737. doi:10.3760/cma.j.issn.1673-0860.2017.10.004. YANG Qingwen, XU Wen, GUO Wei, et al. A retrospective analysis of CO2 laser and microdebrider for the treatment of severe juvenile on-set recurrent respiratory papillomatosis[J]. Chinese Journal of Otorhinolaryngology Head and Neck Surgery, 2017, 52(10): 733-737. doi:10.3760/cma.j.issn.1673-0860.2017.10.004.
[16] Hendriksma M, van Loon Y, C Klop WM, et al. Quality of life and voice outcome of patients treated with transoral CO(2)laser microsurgery for early glottic carcinoma(T1-T2): a 2-year follow-up study [J]. Eur Arch Otorhinolaryngol,2019,276(3):805-814. doi: 10.1007/s00405-019-05348-1.
[17] Ford DA. Safety considerations for laser surgery of the airway[J]. AORN J, 2018, 107(3): P15-P16. doi:10.1002/aorn.12108.
[18] Strong MS, Vaughan CW, Healy GB, et al. Recurrent respiratory papillomatosis[J]. Ann Otol Rhinol Laryngol, 1976, 85(4): 508-516. doi:10.1177/000348947608500412.
[19] Papaspyrou G, Schick B, Papaspyrou S, et al. Retrospective analysis of laser vs other therapeutic modalities for laryngeal papillomatosis: European multicenter study[J]. j buon, 2016, 21(5): 1274-1278.
[20] 雷文斌, 刘其洪. CO2激光手术治疗复发性呼吸道乳头状瘤[J]. 山东大学耳鼻喉眼学报, 2018, 32(6): 8-12. doi:10.6040/j.issn.1673-3770.1.2018.014. LEI Wenbin, LIU Qihong. Progress in the treatment of recurrent respiratory papillomatosis using a CO2 laser[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2018, 32(6): 8-12. doi:10.6040/j.issn.1673-3770.1.2018.014.
[21] Bowles PF, Liu A, Harries ML. CO2 laser “Ablation Suction” technique for treatment of laryngeal recurrent respiratory papillomatosis[J]. Clin Otolaryngol,2019,44(5):884-885.doi: 10.1111/coa.13278.
[22] Ilmarinen T, Auvinen E, Hiltunen-Back E, et al. Transmission of human papillomavirus DNA from patient to surgical masks, gloves and oral mucosa of medical personnel during treatment of laryngeal papillomas and genital warts [J]. Eur Arch Otorhinolaryngol,2012,269(11):2367-2371.doi: 10.1007/s00405-012-2049-9.
[23] Zeitels SM, Akst LM, Burns JA, et al. Office-based 532-nm pulsed KTP laser treatment of glottal papillomatosis and dysplasia[J]. Ann Otol Rhinol Laryngol, 2006, 115(9): 679-685. doi:10.1177/000348940611500905.
[24] Kuet ML, Pitman MJ. Photoangiolytic laser treatment of recurrent respiratory papillomatosis: a scaled assessment[J]. J Voice, 2013, 27(1): 124-128. doi:10.1016/j.jvoice.2012.07.003.
[25] Lechien JR, Burns JA, Akst LM. The use of 532-nanometer-pulsed potassium-titanyl-phosphate(KTP)laser in laryngology: a systematic review of current indications, safety, and voice outcomes[J]. Ear Nose Throat J, 2020: 145561319899183. doi:10.1177/0145561319899183.
[26] Pynnonen M, Brinkmeier JV, Thorne MC, et al. Coblation versus other surgical techniques for tonsillectomy[J]. Cochrane Database Syst Rev, 22(8):CD004619. doi: 10.1002/14651858.CD004619.pub3.
[27] Hao F, Yue LY, Yin XY, et al. Low-temperature radiofrequency coblation reduces treatment interval and post-operative pain of laryngotracheal recurrent respiratory papillomatosis[J]. Biosci Rep, 2020, 40(5): BSR20192005. doi:10.1042/bsr20192005.
[28] 魏锐文, 范敏, 崔榕, 等. CO2激光与等离子两种方法治疗喉乳头状瘤的疗效对比[J]. 四川医学, 2017, 38(7): 787-790. doi:10.16252/j.cnki.issn1004-0501-2017.07.021. WEI Ruiwen, FAN Min, CUI Rong, et al. Comparative study on therapeutic effectiveness of CO2 laser and low-temperature plasma on laryngeal Papilloma[J]. Sichuan Medical Journal, 2017, 38(7): 787-790. doi:10.16252/j.cnki.issn1004-0501-2017.07.021.
[29] Miller AJ, Gardner GM. In-office vs. operating room procedures for recurrent respiratory papillomatosis[J]. Ear Nose Throat J, 2017, 96(4/5): E24-E28. doi:10.1177/0145561319889538.
[30] del Signore AG, Shah RN, Gupta N, et al. Complications and failures of office-based endoscopic angiolytic laser surgery treatment[J]. J Voice, 2016, 30(6): 744-750. doi:10.1016/j.jvoice.2015.08.022.
[31] Tibbetts KM, Simpson CB. Office-based 532-nanometer pulsed potassium-titanyl-phosphate laser procedures in laryngology[J]. Otolaryngol Clin North Am, 2019, 52(3): 537-557. doi:10.1016/j.otc.2019.02.011.
[32] Araki K, Tomifuji M, Uno K, et al. Feasibility of transnasal flexible carbon dioxide laser surgery for laryngopharyngeal lesions[J]. Auris Nasus Larynx, 2019, 46(5): 772-778. doi:10.1016/j.anl.2019.01.008.
[33] Madden LL, Ward J, Ward A, et al. A cardiovascular prescreening protocol for unmonitored in-office laryngology procedures[J]. Laryngoscope, 2017, 127(8): 1845-1849. doi:10.1002/lary.26481.
[34] Weinstein GS, O'Malley Jr BW, Hockstein NG. Transoral robotic surgery: supraglottic laryngectomy in a canine model[J]. Laryngoscope, 2005, 115(7): 1315-1319. doi:10.1097/01.MLG.0000170848.76045.47.
[35] de Virgilio A, Iocca O, Malvezzi L, et al. The emerging role of robotic surgery among minimally invasive surgical approaches in the treatment of hypopharyngeal carcinoma: systematic review and meta-analysis[J]. J Clin Med, 2019, 8(2): 256. doi:10.3390/jcm8020256.
[36] Tan Wen Sheng B, Wong P, Teo Ee Hoon C. Transoral robotic excision of laryngeal papillomas with Flex® Robotic System: a novel surgical approach[J]. Am J Otolaryngol, 2018, 39(3): 355-358. doi:10.1016/j.amjoto.2018.03.011.
[37] Rey Caro EP, Rey Caro DG, Rey Caro EA. High radiofrequency surgery and chromoendoscopy: a novel surgical technique for the treatment of respiratory papillomatosis[J]. J Voice, 2020. doi:10.1016/j.jvoice.2020.03.021.
[38] Jackowska J, Klimza H, Winiarski P, et al. The usefulness of narrow band imaging in the assessment of laryngeal papillomatosis[J]. PLoS One, 2018, 13(10): e0205554. doi:10.1371/journal.pone.0205554.
[39] Benboujja F, Hartnick C. Clinical and surgical implications of intraoperative optical coherence tomography imaging for benign pediatric vocal fold lesions[J]. Int J Pediatr Otorhinolaryngol, 2018, 114: 111-119. doi:10.1016/j.ijporl.2018.08.036.
[40] Benboujja F, Bowe S, Boudoux C, et al. Utility of optical coherence tomography for guiding laser therapy among patients with recurrent respiratory papillomatosis[J]. JAMA Otolaryngol Head Neck Surg, 2018, 144(9): 831-837. doi:10.1001/jamaoto.2018.1375.
[41] Zhou CY, Sun BC, Wang F, et al. Coblation plus photodynamic therapy(PDT)for the treatment of juvenile onset laryngeal papillomatosis: case reports[J]. World J Surg Oncol, 2014, 12: 275. doi:10.1186/1477-7819-12-275.
[42] Reyes LM, Aguilar JL, Villamor P, et al. Clinical and sociodemographic characteristics associated with disease severity in juvenile recurrent respiratory papillomatosis: a study of 104 patients in a tertiary care pediatric hospital[J]. Int J Pediatr Otorhinolaryngol, 2018, 108: 63-66. doi:10.1016/j.ijporl.2018.02.025.
[1] ZHOU Wenjing, CHEN Xuqing, MA Jun, MA Huaan. Glottic lobular capillary hemangioma: a case report and literature review [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2025, 39(5): 101-103.
[2] ZHAO Jianing, CUI Yuanxin, WANG Dan, ZHAO Ming. Exploration of the relationship between laryngopharyngeal reflux and recurrent respiratory papilloma and its mechanism [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(6): 39-45.
[3] ZHOU Xiaoqing, YAN Yajie, LI Yingchun. Treatment of hoarseness based on physiological function of the liver [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2023, 37(5): 74-79.
[4] LI Shaohua, PENG Hongbin, LU Biaoqing, XU Qingwen. Thyroid cartilage damage and airway invasion caused by tracheogenic cyst: a rare case report [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2023, 37(5): 96-98.
[5] LI Yanan, LIANG Hui. Study progress on the mechanism of human papillomavirus-related oropharyngeal squamous cell carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2023, 37(3): 104-110.
[6] XU Dongjiao, TIAN Xiufen. 232 children with congenital pyriform sinus fistula treated by endoscopic radiofrequency ablation [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2023, 37(2): 56-62.
[7] LI Lijie, TIAN Xiufen. Forty cases of early glottic cancer treated by CO2 laser surgery combined with radiofrequency ablation [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(4): 79-85.
[8] CHEN Guoping, FU Minyi, YE Fei, XU Jianhui. Comparative study of holmium and CO2 laser surgeries for early glottic carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(4): 8-11.
[9] CHENG Liyu, XU Wen. Clinical characteristics of functional dysphonia secondary to inadequate voice rest [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(3): 10-13.
[10] TAN Fengwu, DENG Yaping, LI Kehua. The therapeutic effects of low temperature plasma radiofrequency ablation and CO2 laser surgery on early glottic carcinoma: a Meta-analysis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(6): 63-71.
[11] XU Jinjing, HU Jinghua, WU Yuanqing, DENG Yi, YU Weiwei. Applications of CO2 laser microsurgery on laryngeal precancerous lesions and early glottic laryngeal carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(3): 129-133.
[12] SHEN Min, QU Jining, JIANG Yidao. Evaluation the efficacy of a CO2 laser and traditional exfoliation in the treatment of vocal cord leukoplakia by using objective voice analysis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(1): 67-70.
[13] Zhigang HUANG. Treatment of throat tumors with CO2 laser [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2018, 32(6): 1-3.
[14] Ming LIU. Treatment of epiglottic carcinoma by transoral laser microsurgery [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2018, 32(6): 4-7.
[15] Wenbin LEI,Qihong LIU. Progress in the treatment of recurrent respiratory papillomatosis using a CO2 laser [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2018, 32(6): 8-12.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd