新生儿动脉血血气分析与听力筛查结果相关性

doi:10.6040/j.issn.1673-3770.0.2021.350

Abstract

Abstract: Objective This study aimed to examine the relationship between arterial blood gas and hearing screening test in neonates. Methods The results of hearing screening test and arterial blood gas analysis of 496 newborns in the Neonatal Department of Shanghai Children's Medical Center were retrospectively analyzed. Results The pass rate of automated auditory brainstem response(AABR), distortion product otoacoustic emissions(DPOAE)and acoustic immittance is 61.9%(307/496), 61.3%(304/496), 90.1%(447/496)and 56.7%(281/496)respectively. There were significant differences in the pass rates of the three hearing screening methods(χ2=131.00, P<0.001). The pass rate of AABR was in extremely strong consistency with that of DPOAE(Kappa=0.817, P<0.001), while the pass rate of both AABR and DPOAE were in very weak consistency with that of acoustic immittance(Kappa=0.262 and 0.256, respectively. all P<0.001). Univariate Logistic regression analysis showed that the failure of hearing screening was correlated with increased lactic acid(OR=0.544, P=0.001), increased partial pressure of carbon dioxide(OR=1.917, P=0.009)and decreased pH value(OR=1.692, P=0.021). Multivariate Logistic regression analysis showed that failed hearing screening results were correlated with increased lactic acid(OR=0.627, P=0.018)and decreased partial oxygen pressure(OR=1.493, P=0.047). No significant correlations were found between hearing screening and the results of partial pressure of carbon dioxide, pH and blood oxygen saturation(P>0.05). Conclusion Neonatal hypoxia and the accompanying change of blood gas might have an impact on hearing screening results.

Key words: Hearing screening, Lactic acid, Arterial blood pH, Oxygen partial pressure, Carbon dioxide partial pressure, Oxygen saturation

CLC Number:

R764.5

PAN Linlin, FANG Xuhua, ZHAI Feng, GUI Yiding, BIAN Zhouliang, CHEN Jie. The correlation between arterial blood gas analysis and hearing screening results in neonates[J].Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(1): 20-24.

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The correlation between arterial blood gas analysis and hearing screening results in neonates

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