ISSN 1673-3770 CN 37-1437/R
Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2022, Vol. 36 ›› Issue (1): 25-30.doi: 10.6040/j.issn.1673-3770.0.2021.401
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MA Xiaobao, LI Yue, SHEN Jiali, SUN Jin, CHEN Xiangping, YANG Jun, CHEN Jianyong
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| [1] | YANG Yang, WANG Xiaoxu, ZHANG Jie. Progress on diagnosis and treatment of middle ear cholesteatoma in children [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(1): 1-6. |
| [2] | XIA Yanyun, ZHONG Dingjuan, WANG Hua, LI Mengting, LI Qian, CHEN Jiao, HE Shuxi. Effect of high-energy accelerated corneal collagen cross-linking on the ocular surface of keratoconus [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(6): 42-51. |
| [3] | ZHANG Ying, LEI Yulin, MA Zhixing, YANG Xinghua, ZHANG Jing, HOU Jie. Early clinical observation of corneal densitometry after SMILE combined with rapid corneal cross-linking [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(6): 52-58. |
| [4] | LIU Yi, YU Mingkun, SUN Wei, SHAO Zhen, HU Yuanyuan, BI Hongsheng. The effectiveness and safety of orthokeratology on controlling myopia of children: a meta-analysis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(6): 92-100. |
| [5] | WU Dipanpan, CUI Xinhua, GUO Ying, GENG Bo, GAO Fangfang, LIANG Hui. Narrow band imaging might contribute to the diagnosis of laryngopharyngeal reflux [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(3): 31-36. |
| [6] | LI Wei, ZHANG Bin. Effects of optimal pulse technology combined with meibomian gland massage to treat meibomian gland dysfunction [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(2): 105-109. |
| [7] | TIAN Tianjie, ZHANG Zixion, YANG Fei, ZHOU Yi. Effects of palatal arch suturing on postoperative hemorrhage after tonsillectomy [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(1): 82-85. |
| [8] | WANG Lin, WANG Ting, SUN Kaijian, WANG Da, CHEN Linlin. Treatment of 48 cases of canaliculitis with small canalicular incision combined with RS-type lacrimal drainage tube [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(1): 104-108. |
| [9] | CUI Xiaohuan, LI Lina, ZHANG Yanping, JIANG Xingwang, BI Xinxin, RAN Taotao, WU Yingying, LIU Yali. Application of the improved vacuum sealing drainage device in the treatment of refractory pharyngocutaneous fistula [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(6): 49-53. |
| [10] | Vertigo is one of the most important symptom of peripheral vestibular diseases which are difficult to differentially diagnose and manage because multiple disciplines are involved. The premise of effective management is accurate diagnosis of vestibular diseases. With the development of vestibular function examination technology and the deepening of vestibular disease research, great progress has been made in the diagnosis and management of vestibular diseases. The establishment and publication of international classification of vestibular diseases, the introduction of diagnostic standards for various vestibular diseases in the world, the formulation of vestibular disease drugs, surgical specifications and the rapid development of vestibular rehabilitation technology make the diagnosis and management of vestibular diseases more and more standardized and accurate.. Diagnosis and management of peripheral vestibular diseases [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 1-6. |
| [11] | To observe the effect of age on cervical vestibular-evoked myogenic potential(cVEMP)and ocular vestibular-evoked myogenic potential(oVEMP)elicited by galvanic vestibular stimulation(GVS)in healthy subjects. MethodsSixty-one healthy volunteers( ears)aged - years(.±. years)were recruited as study subjects and divided into three groups according to age: -( patients, ears), -( patients, ears), and >( patients, ears)years. Each subject underwent both GVS-cVEMP and GVS-oVEMP. The elicit rate, threshold, p latency, n latency, amplitude, and interaural amplitude asymmetry ratio of both VEMPs were calculated and compared among the age groups. SPSS . software was used for statistical analyses. ResultsThe elicit rates of GVS-cVEMP were .%, .%, and .% in age groups of -, -, and > years, respectively, without any statistically significant difference among groups(P>.). However, the elicit rates of GVS-oVEMP were .%, .%, and .% in age groups of -, -, and > years, respectively, showing a decreased tendency with growing age(PP>.). However, growing age showed decreased elicit rate, increased threshold, and decreased amplitude of oVEMP(P<.)but no difference in the n latency, p latency, or amplitude asymmetry ratio. ConclusionWith growing age, the function of peripheral vestibular system decreased, which might affect GVS-cVEMP and GVS-oVEMP.. Effects of aging on galvanic vestibular stimulation elicited vestibular evoked myogenic potential [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 7-13. |
| [12] | To establish a new grade of vestibular function abnormality in patients with Menieres disease(MD)and to preliminarily investigate its clinical significance and correlation with the hearing stage. MethodsClinical data of patients with unilateral intractable MD hospitalized from January to December were retrospectively reviewed. All patients underwent pure-tone audiometry, cervical vestibular-evoked myogenic potential(cVEMP)testing, ocular VEMP(oVEMP)testing, the video head impulse test(vHIT), and the caloric test. Abnormal semicircular canal function was defined as an abnormal vHIT or caloric test result. Abnormal saccule function was defined as an abnormal cVEMP. Abnormal utricle function was defined as an abnormal oVEMP. Vestibular function grade Ⅰ was defined when the utricle, saccule, and semicircular canal were normal. Vestibular function grade Ⅱ was defined when the utricle, saccule, or semicircular canal was abnormal. Vestibular function grade Ⅲ was defined when two structures among the utricle, saccule, and semicircular canal were abnormal. Finally, vestibular function grade Ⅳ was defined when the utricle, saccule, and semicircular canal were all abnormal. ResultsWe enrolled cases of MD, including , , , and cases in stages Ⅰ, Ⅱ, Ⅲ, and Ⅳ, respectively. The pure-tone average(PTA)hearing at Hz, kHz, and kHz was .±. dB HL in the ears with MD. The abnormal rates of cVEMP, oVEMP, vHIT, and caloric test results were .%, .%, .%, and .%, respectively. According to the grade of vestibular function abnormality, , , , and cases were in grades Ⅰ, Ⅱ, Ⅲ, and Ⅳ, respectively. The vestibular function stage significantly correlated with the PTA(Pr=.), MD stage(P., r=.), and disease duration(P=., r=.). The vestibular function stage did not significantly correlate with patient age(P=.). ConclusionThe rates of abnormal otolith and semicircular canal functions increase with the development of MD. Therefore, patients with MD can be accurately assessed with precise testing of the utricle, saccule, and semicircular canals. The status of the development of MD is reflected in the hearing and vestibular function stages. The combined assessment of hearing and vestibular functions can provide a useful reference for the treatment and prognosis of patients with MD.. A new grade of vestibular function abnormality in Menieres disease: a pilot study [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 14-19. |
| [13] | To record the bone-conducted vestibular-evoked myogenic potential(BC-VEMP)in order to provide a reference for the clinical evaluation of vestibular function in normal-hearing children. MethodsThirty-one normal-hearing children(62 ears)aged 4-12 years were selected to undergo BC-VEMP determination. These children were divided into two groups according to age. Those aged 4-5 years(11 children, 22 ears)belonged to one group while those aged 6-12 years(20 children, 40 ears)belonged to the other. A 60 dB nHL was used as the initial stimulus intensity by which the N1 latency, P1 latency, n1-p1 interval, n1-p1 amplitude, amplitude asymmetry ratio, and threshold of cervical VEMP(CVMP)and ocular VEMP(ocular VEMP)were recorded. The SPSS software was used for statistical analysis. ResultsThere was no significant difference in P1, N1 latency, P1-N1 wave interval, P1-N1 amplitude, threshold, and amplitude asymmetry ratio of BC-oVEMP between the 4-5-year-old and the 6-12-year-old groups(P>0.05). There was no significant difference in N1, P1 latency, n1-p1 wave interval, n1-p1 amplitude, threshold, and amplitude asymmetry ratio of BC-VEMP between the two groups(P>0.05). ConclusionBC-VEMP is a feasible auxiliary examination of vestibular function. The establishment of normal values of BC-VEMP in different age groups can provide a reference for clinical evaluation of vestibular function in children.. The establishment of a normal value of bone-conducted vestibular-evoked myogenic potential in normal-hearing children [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 72-77. |
| [14] | Sudden sensorineural hearing loss(SSNHL)is defined as a decease in hearing ≥30 dB HL affecting at least three consecutive frequencies with no identifiable cause within 72 h. A possible cause is inner ear hemorrhage. However, detecting inner ear hemorrhage is difficult with conventional magnetic resonance imaging(MRI)sequences. Some studies showed that the 3-dimensional fluid attenuated inversion recovery(3D-FLAIR)MRI sequence could sensitively detect inner ear hemorrhage in SSNHL patients. In this article, we review the related literature about the clinical application of the 3D-FLAIR MRI sequence to evaluate SSNHL caused by inner ear hemorrhage.. The role of three-dimensional fluid attenuated inversion recovery magnetic resonance imaging in diagnosis of sudden sensorineural hearing loss caused by inner ear hemorrhage [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 97-101. |
| [15] | This study was aimed at exploring the effects of light-emitting diode(LED)light of different peak wavelengths(622.791, 509.699, and 462.826 nm)on the rat lens, including damage to the morphology of the lens epithelial cells. Further, we tested the activities of the antioxidant enzymes superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px)in the lens and compared the malondialdehyde(MDA)activity in the lens after irradiation by LED of different wavelengths. MethodsSprague Dawley rats were irradiated with LED light of different peak wavelengths(color temperature=4 500 K; illuminance: 500 lux)12 h a day for 5 days. Hematoxylin and eosin(HE)staining was used to observe the paraffin sections of rat lens epithelial cells. The activities of SOD, GSH-Px, and MDA in the lens were detected by the automatic biochemical analyzer. ResultsHE staining showed that lens epithelial cells in the control group were flat, monolayer, and uniform. In the blue-light group, lens epithelial cells were disordered, swollen, and changed from a single layer to double or even multiple layers. In the green-light group, lens epithelial cells were slightly swollen, and some areas showed a double-layer arrangement. In the red-light group, lens epithelial cells were flat, monolayer and uniform too. MDA activities in the rat lens of the control and red-, green-, and blue-light groups were approximately 0.004 3, 0.004 4, 0.015 6, and 0.017 8 U/mgprot, respectively. There were no significant differences between the red-light and control groups(P>0.05), but there were significant differences among the other groups(P<0.05). SOD activities in the lens of the control and red-, green-, and blue-light groups were 1.306 7, 7.926 7, 3.070 0, and 2.1233 U/mgprot, respectively, showing significant differences(P<0.05). GSH-Px activities in the lens of the control and red-, green-, and blue-light groups were 1.413 3, 9.793 3, 2.696 0, and 2.159 0 U/mgprot, respectively, showing significant differences(P<0.05). ConclusionThe influence of LED light on rat lens epithelial cells is wavelength-dependent. Shorter wavelengths of LED light are associated with greater changes in the lens epithelial cell morphology, greater effects of SOD and GSH-Px activities in the lens, and more lipid peroxide accumulation in the lens.. Effect of light-emitting diode light of different wavelengths on the rat lens: a preliminary study [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 138-144. |
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