老年肺炎患者胃食管反流病和咽喉反流性疾病25例

doi:10.6040/j.issn.1673-3770.0.2024.062

Abstract

Abstract: Objective To investigate the clinical characteristics of gastroesophageal reflux disease(GERD)and laryngopharyngeal reflux disease(LPRD)in elderly patients with pneumonia. Methods The study was conducted on elderly patients with pneumonia hospitalized in the respiratory department at the Ninth Medical Center of Chinese PLA General Hospital from January 2022 to December 2023. These patients completed 24-hour Dx-pH monitoring and had complete hospital records. The study involved analyzing the clinical characteristics in patients with gastroesophageal and laryngopharyngeal reflux were analyzed. Results Of the 23 patients who underwent pharyngeal pH monitoring, 10 had a Ryan index score >6.79 in the supine position, one patient had a Ryan index score >9.41 in the upright position, and 16 had a W index greater than 0. Among the 20 patients who underwent 24-hour esophageal Dx-pH monitoring, 3 had a DeMeester score ≥14.72, and 4 had an acid exposure time(AET)≥4.0%. In the laryngopharyngeal reflux group, pneumonia was observed in the right upper lobe in 7 patients(63.6%), compared to 4 patients(33.3%)in the non- laryngopharyngeal reflux group. CURB-65 scores were 2.45±0.82 for patients with laryngopharyngeal reflux and 2.08±0.79 for those without laryngopharyngeal reflux. Among patients with laryngopharyngeal reflex, 4(36.4%)died within 28 days, while only one(8.3%)patient without laryngopharyngeal reflux died during the same period. Conclusions Elderly patients with pneumonia are susceptible to GERD and LPRD. Among patients with laryngopharyngeal reflux, inflammation in the upper lobe of the right lung and the lower lobe of the left lung is high, and the mortality rate in this group is significantly increased.

Key words: Pneumonia in the elderly, laryngopharyngeal reflux disease, gastroesophageal reflux disease, 24-hour pH monitoring

CLC Number:

R766.5

LI Fengjiang, WEI Jie, LIU Hongdan, ZHANG Li, ZHAO Weichao, WU Nana, WANG Lei, WU Wei, WANG Ruijuan. Gastroesophageal reflux disease and laryngopharyngeal reflux disease in 25 elderly patients with pneumonia[J].Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(6): 103-107.

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