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Clinical observations following thermal pulsation system treatment for mild and moderate meibomian gland dysfunction
- LI Shang, ZHANG Wei, LU Hongshuang, ZANG Yunxiao, DONG Hongwei, GUO Chungang, PAN Zhiqiang, JIE Ying
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JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2018, 32(3):
91-95.
doi:10.6040/j.issn.1673-3770.0.2017.495
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Objective To assess the clinical outcomes of using Lipiflow thermal pulsation system, on mild to moderate meibomian gland dysfunction(MGD), during treatment and at the 3 and 6 months follow up visit. Methods A retrospective analysis of clinical data of MGD patients who sought medical help and underwent LipiFlow treatment at Beijing Youan Hospital from March to November 2016, was conducted. The participants answered a SPEED questionnaire for before, and 3 and 6 months after treatment. In addition, other indicators assessed included, partial blinks(PB), lipid layer thickness(LLT), tear break-up time(TBUT), Schirmer I test(SIT), and meibomian glands yielding liquid secretion(MGYLS). Results SPEED scores at 3 and 6 months, after treatment, were(10.20±3.57)and(9.87±3.68)respectively, significantly lower than(12.13±2.42)before treatment. PB rate assessed at the same time points after treatment was 60% and 62.4%, significantly different than 72.24% before treatment. The other scores, in the order before treatment, 3 and 6 months after treatment, were as follows: LLT scores were(71.70±21.23),(72.03±20.52), and(74.60±20.07)nm; TBUT scores were(5.37±2.19),(6.33±2.34), and(6.40±2.50)s; SIT scores were(5.30±4.41),(5.93±4.51), and(7.43±7.26)mm; and MGYLS scores were(3.50±2.11),(4.23±1.99), and(3.83±1.97). No statistically significant differences were found for LLT, TBUT, SIT, and MGYLS scores. Conclusion Subjective symptoms were improved by thermal pulsation system treatment in mild and moderate MGDs, and PB rates were lowered. The efficacy lasted for up to 6 months.
